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Hotels in Chaffee

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Check prices for these dates

Tonight
Dec 26 - Dec 27
Tomorrow
Dec 27 - Dec 28
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

Where to stay in Chaffee?

Property amenity
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
3.0 star property
9.4 out of 10, Exceptional, (1000)
The price is CNY630
CNY725 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Drury Inn & Suites Sikeston, MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Chaffee

The region around Chaffee is home to attractions such as Isle Casino Cape Girardeau and Show Me Center.

See all hotels in Chaffee
The Missouri State Tree - Dogwood
Photo by Abbie Moon
Open Photo by Abbie Moon

Check out reviews of Chaffee hotels guests love

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"This our favorite place to stop for a good night sleep. "
Eileen 1-night trip
Posted 4 days ago
Drury Inn & Suites Sikeston, MO

Frequently asked questions

How much does a hotel room cost in Chaffee?
You can discover great hotels in Chaffee from CNY455 with properties to suit all budgets and needs. To find an affordable hotel in Chaffee that meets all of your requirements, just apply filters on Hotels.com and sort hotels by "Price: low to high".
How can I find deals and earn rewards at Chaffee hotels?
Discover great deals on Chaffee hotel stays with Hotels.com. You can also look at hotel prices mid-week or during the low season to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Chaffee hotels.
Can I book Chaffee hotels with free cancellation?
To book a refundable Chaffee hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
What hotels do travelers like in Chaffee?
Guests like Drury Plaza Hotel Cape Girardeau Conference Center, Drury Inn & Suites Cape Girardeau and Pear Tree Inn Cape Girardeau Near the Medical Center.
Can I book a refundable hotel in Chaffee?
If you need the flexibility to change your plans to Chaffee, most properties offer refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in Chaffee be like during my vacation?
The warmest months in Chaffee are usually July and August with an average temp of 76°F. January and February are the chilliest months when the average temp is 40°F. The rainiest months are April and March.
Why should I book my Chaffee accommodation with Hotels.com?
There are lots of reasons to book your Chaffee trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.