Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Isola on Hotels.com. These Isola hotels consistently deliver on quality, location and traveler experience. Last updated on October 5, 2026.
1. Galatea e Giardino delle Esperidi apartments with pool by Wonderful Italy
Just 15 minutes from Lungomare di Ortigia, this cozy apartment offers a fully equipped kitchen for preparing local delicacies. Enjoy free WiFi, satellite TV, and air conditioning while exploring nearby Spiaggia Punta del Pero.
Experience Mediterranean charm at this Syracuse hotel featuring a refreshing outdoor pool with poolside bar. Just a 10-minute drive from Lungomare di Ortigia, guests enjoy free breakfast, WiFi, and parking. The rooftop terrace offers scenic relaxation after exploring nearby attractions.
Immerse yourself in charming Syracuse at this family-friendly hotel where helpful staff earn top marks from guests. Enjoy complimentary breakfast, free WiFi, and convenient 24-hour room service while staying near Palazzo Montalto and Arkimedeion Museum.
Immerse yourself in coastal charm at this beach hotel with free breakfast and WiFi. Take in stunning views from the rooftop terrace, cool off in the seasonal outdoor pool, or enjoy the bar. Near Pista Ciclabile Siracusa and just 7 minutes from Syracuse Station.
Step into serenity at this Syracuse spa haven adjacent to a golf course. Enjoy indoor swimming, 3 bars including a poolside option, and authentic Italian dishes at Ristorante Panoramico. Fontane Bianche Beach sits nearby, with free breakfast, WiFi, and parking.
This business-friendly Sicilian retreat sits steps from Fontane Bianche Beach with an outdoor pool and poolside bar. Unwind in the sauna after exploring nearby Pineta del Gelsomineto Beach, then enjoy the restaurant, snack bar, and free breakfast.
Float between 2 outdoor pools at this serene retreat near Ciane River and Saline Nature Reserve. The spa offers massages and Ayurvedic treatments, while children enjoy the free kids' club. With a fitness center, poolside bar, and café, this Syracuse gem includes breakfast and parking.
Immerse yourself in Sicilian charm at this business-friendly hotel, just a 10-minute walk from Lungomare di Ortigia and Syracuse Forum Ruins. Enjoy free breakfast and WiFi, plus convenient room service. Syracuse Station is only 9 minutes away on foot.
Feel the coastal breeze from a stunning rooftop terrace at this Syracuse spa hotel. Near Catacombs of St. John and Roman Amphitheatre, it offers massages, facial treatments, and an outdoor pool with poolside bar. Just a 16-minute walk from the train station.
Experience Fusion cuisine at Akademia Restaurant after a day at the spa with massages and facials. This Art Deco hotel offers free breakfast, WiFi, and parking, with Capuchin Quarry nearby and 24-hour fitness options for active travelers.
Escape to this Syracuse haven where the rooftop terrace offers stunning panoramas. After a massage or hydrotherapy at the full-service spa, enjoy a meal at the restaurant or drinks at the bar. The indoor pool and fitness center complete your rejuvenating Italian retreat.
Escape to this luxurious Syracuse retreat where Mediterranean cuisine meets poolside relaxation. Just 15 minutes from Ortigia, enjoy the spa treatments, fitness center, and poolside bar. Helpful staff ensure a flawless stay near Cantine Gulino.
Immerse yourself in Sicilian charm at this train station-adjacent hotel with complimentary breakfast and WiFi. Relax at the terrace bar after exploring nearby Antico Mercato and Lungomare di Ortigia, just a 15-minute walk from Syracuse Station.
Wake up to a complimentary buffet breakfast at this intimate Syracuse hotel near the train station. Explore nearby Jewish Bath and Museum of Cinema before returning to relax with free WiFi in your comfortable suite.
This charming Syracuse hotel sits just steps from Lungomare di Ortigia, offering a peaceful rooftop terrace with scenic views. Enjoy free continental breakfast daily and unwind with drinks at the bar. Near Spiaggetta di Cala Rossa with attentive staff to enhance your stay.
This luxurious beachfront retreat offers a serene private shoreline with safe swimming and panoramic views. Enjoy the outdoor pool, indulge in Italian cuisine at Nesos restaurant, or unwind on the rooftop terrace after a spa massage.
Immerse yourself in Syracuse charm at this stylish hotel with Italian cuisine at Ristorante Amunì. Steps from the Cathedral and Palazzo Beneventano, with attentive staff ready to enhance your stay. The on-site bar offers a perfect evening unwind spot.
This Syracuse hotel offers a seasonal outdoor pool, garden terrace, and convenient 24-hour fitness center. Just a short drive from Lungomare di Ortigia and Ciane River, guests appreciate the helpful staff, free WiFi, and complimentary parking.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
If want to top up your tan, you might want to head out to Spiaggia Punta del Pero, located 0.4 mi (0.7 km) from central Isola. Catch the sunset by the shore at Spiaggia di Punta Carrozza, just a short walk away.
The hotel itself was like a beautiful oasis in a not so attractive area of the city. The room was very nice and spacious and the pool was very nice as well.
This charming hotel is in a great location overlooking the sea and within easy walking distance of everything in historic Ortygia. Our room was spotlessly clean and came with a small balcony that overlooked the street and ancient church below. There is an amazing rooftop terrace, open to guests, where one can sunbathe or eat a meal overlooking the absolutely beautiful blue Mediterranean. The helpful staff assisted us as we found a nearby parking spot for our car and gave us a paper to put on the...
The hotel is located close to some of the major attractions...the archeological museum and the Greek theater are not far away. The rooms are comfortable and well maintained. There is an excellent cable service that includes CNN and the BBC. The breakfasts are superb. The management is friendly and attentive. The hotel has a certain classic charm. I have stayed here many times and am happy to recommend this hotel.
One of the most confortable rooms we have stayed in this trip. Excellent location, large room, very confortable bed, good AC within walking distance of the old town and the histroic sites, ect.
We were sorry not to have more time here. . It has 2 beautiful pools and the room was large and had a high wooden ceiling which was very attractive. We had a good dinner in the restaurant. I don't know why they picked the location but it's close to Syracuse yet you're in the countryside.
When we arrived we needed to change the room and they were very helpful with 2 options. We got the one facing the ocean. Breakfast was very good. I had to wash my car and one of the helpers at the reception drove with her motorcycle in front of me until we got the place. We used the gym and was very good. The helpers at the reception are young women and were excellent service. The top fllor (4) is an open terrace very nice to stay in the afternoon. The place was not dark at all as I read in...
This is a small boutique hotel, located about 15 min walk from the island of Ortigia. The walk is easy, safe, and interesting. It is down one of the main streets. The same walking distance is toward archeological park. I liked the location of this hotel - it was right in the middle, next to a lovely park and had a free street parking.
This hotel has a roof-top terrace with jacuzzi (which is lovely after a long day of exploring) and a restaurant. The restaurant is fine dinning with unique...
La Casa di Melo was our first stay at an agriturismo and without a doubt, one of the highlights on a 10 day Sicilian vacation. The fixed price dinner was the best we had and the easy going service was extremely pleasing and relaxing. Breakfast was equally outstanding with all types of homemade, fresh Sicilian goodiesI I wish we had been able to spend more time and use the pool and walk the orchards.
My hotel room was very clean and staffs were very kind to me.
And your hotel was close enough to go to the sea in swimsuit.
I'd like to visit your hotel again.
We stayed here for one night and wish we could have stayed longer. We didn’t have time to use the spa but we did go to the outdoor pool for a bit. The pool was amazing and the outdoor bar was a nice touch. The breakfast was very good and the room overlooked the race track so you can watch the horses warm up in the morning. It was an overall excellent hotel for the price.
Staff very kind.
One of the travelers uses a wheelchair, the hotel was perfect for his condition.
Breakfast excellent!
Great location if you have transportation
I can't say enough great things about this hotel. It's in a great location, easy to get to, helpful staff, and has an amazing view. The parking wasn't really an issue either.
We were greeted with two glasses of prosecco and some bruschetta. We hope to return someday.
Ideal place to decompress, reflect, energize, and well needs self-care. Location is located away from the congestion of busy towns, so, it’s a great place to relax.
The room was big and spacious. The hotel was close to everything, you dont need no car. Breakfast was in nearby bakery which only allows 1 food and 1 beverage. Host is nice though she didnt come on site. She gladly answered all my questions on whats app.
Nice facility a little off the beaten track. There is a decent breakfast included, but no dinner option. A car is essential and the very narrow country lanes are not easy to navigate at night. There are many positives, including the views on clear days, a very attentive staff at breakfast and for house cleaning. Room for improvement could be for someone to be present at check-in time and not having to wait 45 minutes for him to show up ("I was only late by a few minutes"). As well, the pool...
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What are some popular hotels in central Isola?
For hotels in central Isola, check out Palazzo Artemide - VRetreats, SLH Collection and Algila' Ortigia Charme Hotel. Travelers love Palazzo Artemide - VRetreats, SLH Collection for its location, as well as the restaurant, bar/lounge and coffee shop/cafe this hotel offers. Algila' Ortigia Charme Hotel is another popular central hotel with a restaurant, a bar/lounge and a free continental breakfast. Ortigia and Santa Lucia are some of the most central neighborhoods for your Isola vacation.