Hotels in St. Charles

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Tonight
May 1 - May 2
Tomorrow
May 2 - May 3
This weekend
May 1 - May 3
Next weekend
May 8 - May 10

Where to stay in St. Charles?

Panoramic House | Living area | Flat-screen TV
Big River Escape Grandview Manse
Big River Escape Grandview Manse
3.0 star property
Altura
10.0 out of 10, Exceptional, (4 reviews)
Enjoy serene Minnesota comfort with a fully-equipped kitchen and modern conveniences. Just a short drive from John Latsch State Park and Walnut Grove Golf Course, this cozy retreat offers free WiFi, parking and laundry facilities.
The price is CNY2,508
CNY2,693 total
includes taxes & fees
May 10 - May 11
Big River Escape Grandview Manse
In-room safe, desk, blackout drapes, iron/ironing board
Days Inn by Wyndham Winona
Days Inn by Wyndham Winona
2.0 star property
Winona
7.8 out of 10, Good, (1,000 reviews)
Wake up to free breakfast at this business-friendly Winona hotel, where a 24-hour fitness center keeps you energized. Just minutes from Remlinger Muscle Cars, enjoy clean rooms, helpful staff, and convenient parking near Mississippi River attractions.
The price is CNY436
CNY487 total
includes taxes & fees
May 3 - May 4
Days Inn by Wyndham Winona
Studio Suite, 1 King Bed, Non Smoking | Desk, blackout drapes, iron/ironing board, free cribs/infant beds
AmericInn by Wyndham Winona
AmericInn by Wyndham Winona
3.0 star property
Winona
9.0 out of 10, Wonderful, (930 reviews)
Wake up to free breakfast at this Mississippi River hotel offering a hot tub for relaxation after workouts in the fitness center. The friendly staff earns praise from guests, while Remlinger Muscle Cars and Westfield Golf Club wait nearby. Free WiFi and parking round out your stay.
The price is CNY808
CNY902 total
includes taxes & fees
May 10 - May 11
AmericInn by Wyndham Winona
Exterior
The Wen Inn formerly Andor Wenneson
The Wen Inn formerly Andor Wenneson
2.0 star property
Peterson
9.8 out of 10, Exceptional, (63 reviews)
This historic inn offers hiking and biking paths right outside your door, with free breakfast featuring local cuisine. Just minutes from Magelssen Bluff Park, guests enjoy complimentary WiFi, parking, and peaceful garden views.
The price is CNY595
CNY652 total
includes taxes & fees
May 27 - May 28
The Wen Inn formerly Andor Wenneson
Front of property
Stone Mill Hotel & Suites
Stone Mill Hotel & Suites
3.0 star property
Lanesboro
9.2 out of 10, Wonderful, (673 reviews)
Nestled alongside a scenic golf course, this charming hotel offers complimentary breakfast, WiFi, and parking. Outdoor enthusiasts can explore nearby hiking trails, kayaking spots, and seasonal skiing, while cultural attractions and the praised staff enhance your countryside escape.
The price is CNY718
CNY771 total
includes taxes & fees
May 3 - May 4
Stone Mill Hotel & Suites
Cabin, 1 Bedroom | Living area | 32-inch Smart TV with digital channels, TV, Netflix
Big River Escape Riverside Cabins
Big River Escape Riverside Cabins
3.0 star property
Cochrane
9.2 out of 10, Wonderful, (45 reviews)
Nestled along the Mississippi, this Cochrane retreat offers cabins with full kitchens and Smart TVs. Enjoy hiking trails and mountain biking nearby, then relax with Netflix after exploring Walnut Grove Golf Course or Danzinger Vineyards.
The price is CNY798
CNY842 total
includes taxes & fees
May 19 - May 20
Big River Escape Riverside Cabins
Reception
Spark by Hilton Rochester South
Spark by Hilton Rochester South
3.0 star property
Rochester
9.2 out of 10, Wonderful, (457 reviews)
Within 10 minutes of Mayo Clinic, this welcoming Rochester hotel offers free breakfast, WiFi, and parking. Swim in the indoor pool, stay fit at the on-site gym, and experience friendly service that guests consistently praise.
The price is CNY538
CNY619 total
includes taxes & fees
May 31 - Jun 1
Spark by Hilton Rochester South
Reception
Hampton Inn Rochester-South
Hampton Inn Rochester-South
2.5 star property
Rochester
9.0 out of 10, Wonderful, (1,002 reviews)
Unwind in this tranquil retreat just 5 minutes from Mayo Clinic. After enjoying the free breakfast, take a refreshing dip in the indoor pool or relax in the hot tub. The helpful staff, free WiFi, and convenient parking enhance your stay near Apache Mall.
The price is CNY586
CNY675 total
includes taxes & fees
May 22 - May 23
Hampton Inn Rochester-South
Exterior
Green Gables Inn
Green Gables Inn
2.0 star property
Lanesboro
9.6 out of 10, Exceptional, (75 reviews)
Nestled in Lanesboro with free continental breakfast served each morning, this welcoming inn offers complimentary WiFi and parking. Discover nearby Root River and Sylvan Park during your stay, with convenient access for outdoor adventures.
The price is CNY745
CNY800 total
includes taxes & fees
May 4 - May 5
Green Gables Inn
Lobby
The Rushford Inn
The Rushford Inn
3.0 star property
Rushford
8.0 out of 10, Very Good, (1 review)
The price is CNY1,086
CNY1,198 total
includes taxes & fees
May 18 - May 19
The Rushford Inn
Exterior
Holiday Inn Express Rochester South - Mayo Area by IHG
Holiday Inn Express Rochester South - Mayo Area by IHG
2.5 star property
Rochester
8.8 out of 10, Excellent, (1,001 reviews)
Relax at this Rochester hotel just minutes from Mayo Clinic. Wake up to a free hot breakfast, unwind in the indoor pool, or keep up your routine at the fitness center. Clean rooms with fridges and microwaves offer comfort after hospital visits.
The price is CNY629
CNY724 total
includes taxes & fees
May 24 - May 25
Holiday Inn Express Rochester South - Mayo Area by IHG
Family Cottage, Park View | Living area | 42-inch Smart TV with digital channels, streaming services, printers
Big River Escape Parkside Bungalow
Big River Escape Parkside Bungalow
3.0 star property
Winona
10.0 out of 10, Exceptional, (1 review)
Escape to this cozy cottage with easy access to hiking trails and a convenient 16-minute walk to Winona Station. Enjoy modern comforts including a Smart TV, washer/dryer, and printer while exploring nearby Huff Center and Altra Federal Credit Union Stadium.
The price is CNY1,407
CNY1,571 total
includes taxes & fees
May 4 - May 5
Big River Escape Parkside Bungalow
Terrace/patio
Hyatt House Rochester/Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
3.0 star property
Downtown Rochester
9.0 out of 10, Wonderful, (1,000 reviews)
This Rochester hotel offers a free area shuttle to nearby Mayo Clinic. Enjoy the indoor pool and hot tub after a long day, or grab a drink at the bar. The onsite fitness center, convenient in-room refrigerators, and helpful staff ensure a stress-free stay.
The price is CNY949
CNY1,093 total
includes taxes & fees
May 31 - Jun 1
Hyatt House Rochester/Mayo Clinic Area
Indoor pool, open 7:00 AM to 10:00 PM, sun loungers
Kahler Inn and Suites - Mayo Clinic Area
Kahler Inn and Suites - Mayo Clinic Area
3.5 star property
Downtown Rochester
8.0 out of 10, Very Good, (1,562 reviews)
A serene choice near Mayo Clinic, this Rochester hotel provides peaceful accommodations with free breakfast. Visit the on-site coffee shop after your fitness center workout. Guests consistently praise the helpful staff, clean rooms, and proximity to Plummer Building.
The price is CNY889
CNY1,024 total
includes taxes & fees
May 30 - May 31
Kahler Inn and Suites - Mayo Clinic Area
Presidential Suite, Multiple Beds | Living area | 55-inch LCD TV with satellite channels, TV
Hilton Rochester Mayo Clinic Area
Hilton Rochester Mayo Clinic Area
3.5 star property
Downtown Rochester
9.6 out of 10, Exceptional, (594 reviews)
Steps from Mayo Clinic, this hotel offers a rejuvenating full-service spa plus 2 restaurants. After treatments, relax in the indoor pool or unwind at the bar. Rooms include microwaves and refrigerators for extended medical stays.
The price is CNY1,172
CNY1,349 total
includes taxes & fees
May 22 - May 23
Hilton Rochester Mayo Clinic Area
Free daily full breakfast
Econo Lodge Mayo Clinic Area
Econo Lodge Mayo Clinic Area
2.0 star property
Rochester
9.0 out of 10, Wonderful, (968 reviews)
Wake up to a free full breakfast at this quiet hotel just 5 minutes from Mayo Clinic. Enjoy complimentary WiFi and parking, plus a 24-hour fitness center. The helpful staff and convenient location near Olmsted County Fairgrounds make this a peaceful choice.
The price is CNY455
CNY524 total
includes taxes & fees
May 24 - May 25
Econo Lodge Mayo Clinic Area
Iron/ironing board, free cribs/infant beds, free WiFi, bed sheets
Baymont by Wyndham Rochester Mayo Clinic Area
Baymont by Wyndham Rochester Mayo Clinic Area
2.5 star property
Rochester
7.2 out of 10, Good, (771 reviews)
The price is CNY407
CNY469 total
includes taxes & fees
May 7 - May 8
Baymont by Wyndham Rochester Mayo Clinic Area
Serves lunch, dinner, and happy hour
AmericInn by Wyndham Rochester Near Mayo Clinic
AmericInn by Wyndham Rochester Near Mayo Clinic
3.0 star property
Rochester
8.2 out of 10, Very Good, (1,292 reviews)
Steps from Mayo Clinic, this tranquil hotel offers an indoor pool and on-site dining at Crooked Pint Ale House. Rooms include microwaves and refrigerators while the quiet environment ensures restful recovery. Free breakfast and parking add convenience.
The price is CNY499
CNY575 total
includes taxes & fees
May 10 - May 11
AmericInn by Wyndham Rochester Near Mayo Clinic
Front of property
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3.0 star property
Rochester
7.2 out of 10, Good, (1,049 reviews)
Situated just a 10-minute drive from Mayo Clinic, this hotel offers a complimentary buffet breakfast each morning. Guests appreciate the spotless rooms, free WiFi, and parking. The fitness center and proximity to local attractions add extra value.
The price is CNY454
CNY523 total
includes taxes & fees
May 24 - May 25
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Lunch and dinner served, American cuisine
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
3.0 star property
Historic Southwest
8.6 out of 10, Excellent, (1,003 reviews)
This serene hotel is a 15-minute walk from Mayo Clinic and Saint Marys Campus. Enjoy the indoor pool, American cuisine at Twigs Tavern and Grille, and complimentary shuttle service. Guests love the helpful staff, free breakfast, and quiet atmosphere.
The price is CNY781
CNY899 total
includes taxes & fees
May 3 - May 4
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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When is the best time to visit St. Charles?

Our prices for hotels in St. Charles are cheapest in March
Price trends for hotels in St. Charles
Pricing is based on two traveler single night rates
View properties in May
Currently viewing crowd sizes and weather for May.
Typical weather for St. Charles
May
High 18°C / low 9°C. Sunny most days.
View properties in May
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May, no crowd data, average high temperature 18 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
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June, no crowd data, average high temperature 24 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
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26°
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July, no crowd data, average high temperature 26 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
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August, no crowd data, average high temperature 26 degrees Celsius, average low temperature 16 degrees Celsius. Sunny most days.
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September, no crowd data, average high temperature 22 degrees Celsius, average low temperature 12 degrees Celsius. Sunny most days.
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October, no crowd data, average high temperature 13 degrees Celsius, average low temperature 5 degrees Celsius. Partly sunny.
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November, no crowd data, average high temperature 5 degrees Celsius, average low temperature -2 degrees Celsius. Partly sunny.
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December, no crowd data, average high temperature -2 degrees Celsius, average low temperature -9 degrees Celsius. Snow likely.
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January, no crowd data, average high temperature -6 degrees Celsius, average low temperature -13 degrees Celsius. Snow likely.
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February, no crowd data, average high temperature -4 degrees Celsius, average low temperature -13 degrees Celsius. Snow likely.
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March, no crowd data, average high temperature 5 degrees Celsius, average low temperature -4 degrees Celsius. Snow likely.
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11°
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April, no crowd data, average high temperature 11 degrees Celsius, average low temperature 2 degrees Celsius. Cloudy most days.
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Monthly weather averages (˚C)

Learn more about St. Charles

St. Charles is well-known for its attractions such as Whitewater State Park and Whitewater River.

See all hotels in St. Charles
St. Charles is a rural Community in South East Minnesota

Check out reviews of St. Charles hotels guests love

Brentwood Inn & Suites

Brentwood Inn & Suites

6/10 Okay
"Clean room and bathroom but very outdated."
Sarah 1-night trip
Posted 2 hours ago
Brentwood Inn & Suites

Frequently asked questions

How much does a hotel room cost in St. Charles?
You can discover great hotels in St. Charles from CNY425 with properties to suit all budgets and needs. If you're after an affordable hotel in St. Charles that meets all of your requirements, set your filters and then sort the results by "Price: low to high".
How can I find deals and earn rewards at St. Charles hotels?
Discover great deals on St. Charles hotel stays with Hotels.com. Take a look at hotel prices mid-week or during the low season as to find those off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on St. Charles hotels.
Can I book St. Charles hotels with free cancellation?
In order to book a refundable St. Charles hotel, simply filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
What accommodations do travelers recommend in St. Charles?
White Valley Motel is an accommodation that is popular with guests.
Can I book refundable accommodations in St. Charles?
If you need the flexibility to change your plans to St. Charles, most properties provide refundable* bookable rates. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in St. Charles be like during my vacation?
July and August are typically the warmest months in St. Charles when the average temp is 67°F. January and February are the coldest months when the average temperature is 22°F. June and May are the months with the most rain.
Why should I book my St. Charles accommodation with Hotels.com?
There are plenty of reasons to book your St. Charles travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.