Hotels in St. Charles

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Jun 19 - Jun 21
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Jun 26 - Jun 28

Where to stay in St. Charles?

Lobby

Comfort Inn & Suites Rochester South Mayo Clinic

Comfort Inn & Suites Rochester South Mayo Clinic
2.0 star property
Rochester
8.8 out of 10, Excellent, (1,011 reviews)
Conveniently located just 0.9 mi from the airport, with a free shuttle service during limited hours. Unwind in the indoor pool and hot tub after exploring nearby Mayo Clinic. Guests love the helpful staff, clean rooms, and free amenities including breakfast, WiFi, and parking.
The price is CNY519
CNY598 total
includes taxes & fees
Jun 21 - Jun 22
Comfort Inn & Suites Rochester South Mayo Clinic
Studio Suite, 1 King Bed, Non Smoking | Desk, blackout drapes, iron/ironing board, free cribs/infant beds

AmericInn by Wyndham Winona

AmericInn by Wyndham Winona
3.0 star property
Winona
9.0 out of 10, Wonderful, (947 reviews)
Wake up to free breakfast at this Mississippi River hotel offering a hot tub for relaxation after workouts in the fitness center. The friendly staff earns praise from guests, while Remlinger Muscle Cars and Westfield Golf Club wait nearby. Free WiFi and parking round out your stay.
The price is CNY799
CNY892 total
includes taxes & fees
Jul 5 - Jul 6
AmericInn by Wyndham Winona
Indoor pool

Holiday Inn Express & Suites Winona by IHG

Holiday Inn Express & Suites Winona by IHG
2.5 star property
Winona
9.2 out of 10, Wonderful, (929 reviews)
Minutes from Sugar Loaf Trailhead, this hotel offers a hot tub, sauna, and children's pool for family fun. Guests love the helpful staff, free breakfast, and 24-hour fitness center. Complimentary parking makes exploring nearby Mississippi River convenient.
The price is CNY940
CNY1,049 total
includes taxes & fees
Jun 18 - Jun 19
Holiday Inn Express & Suites Winona by IHG
Reception

Hampton Inn Rochester-South

Hampton Inn Rochester-South
2.5 star property
Rochester
9.0 out of 10, Wonderful, (1,014 reviews)
Unwind in this tranquil retreat just 5 minutes from Mayo Clinic. After enjoying the free breakfast, take a refreshing dip in the indoor pool or relax in the hot tub. The helpful staff, free WiFi, and convenient parking enhance your stay near Apache Mall.
The price is CNY581
CNY669 total
includes taxes & fees
Jul 12 - Jul 13
Hampton Inn Rochester-South
View from property

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
3.0 star property
Kutzky Park
9.4 out of 10, Exceptional, (716 reviews)
Conveniently located just 5 minutes from Mayo Clinic, this hotel offers free breakfast and area shuttle service. Relax in the indoor pool after a busy day, or maintain your workout at the fitness center. In-room comforts include refrigerators and microwaves.
The price is CNY724
CNY834 total
includes taxes & fees
Jul 3 - Jul 4
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
Lobby

The Rushford Inn

The Rushford Inn
3.0 star property
Rushford
9.4 out of 10, Exceptional, (3 reviews)
The price is CNY968
CNY1,068 total
includes taxes & fees
Jun 16 - Jun 17
The Rushford Inn
Reception

Spark by Hilton Rochester South

Spark by Hilton Rochester South
3.0 star property
Rochester
9.2 out of 10, Wonderful, (501 reviews)
Within 10 minutes of Mayo Clinic, this welcoming Rochester hotel offers free breakfast, WiFi, and parking. Swim in the indoor pool, stay fit at the on-site gym, and experience friendly service that guests consistently praise.
The price is CNY521
CNY600 total
includes taxes & fees
Jun 21 - Jun 22
Spark by Hilton Rochester South
Deluxe Double Room | Down comforters, pillowtop beds, individually decorated

Country Trails Inn & Suites

Country Trails Inn & Suites
2.0 star property
Preston
9.4 out of 10, Exceptional, (120 reviews)
Unwind at this hotel near Old Barn Resort Course, combining country charm with modern comforts. After a morning swim in the indoor pool, relax in the hot tub. Enjoy free breakfast, WiFi, and parking during your Preston getaway.
The price is CNY855
CNY944 total
includes taxes & fees
Jun 16 - Jun 17
Country Trails Inn & Suites
Front of property

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3.0 star property
Rochester
7.4 out of 10, Good, (1,071 reviews)
Situated just a 10-minute drive from Mayo Clinic, this hotel offers a complimentary buffet breakfast each morning. Guests appreciate the spotless rooms, free WiFi, and parking. The fitness center and proximity to local attractions add extra value.
The price is CNY494
CNY568 total
includes taxes & fees
Jun 21 - Jun 22
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Lunch and dinner served

The Plaza Hotel & Suites Winona

The Plaza Hotel & Suites Winona
3.0 star property
Winona
8.6 out of 10, Excellent, (1,012 reviews)
This tranquil Winona retreat features 2 indoor pools and an onsite winery. The River City Grill & Bar serves American cuisine, while rooms include refrigerators and microwaves. Free breakfast, WiFi, and parking complement the serene atmosphere near Sugar Loaf Trailhead.
The price is CNY981
CNY1,095 total
includes taxes & fees
Jun 16 - Jun 17
The Plaza Hotel & Suites Winona
Miscellaneous

Alexander Mansion Bed and Breakfast

Alexander Mansion Bed and Breakfast
3.5 star property
Historic Downtown Winona
9.8 out of 10, Exceptional, (512 reviews)
Discover historic charm at this B&B with complimentary breakfast and parking near Watkins Heritage Museum. Hiking and kayaking opportunities surround this peaceful mansion, while Polish Cultural Institute and Winona Station are just minutes away.
The price is CNY725
CNY810 total
includes taxes & fees
Jun 16 - Jun 17
Alexander Mansion Bed and Breakfast
In-room safe, desk, blackout drapes, iron/ironing board

Days Inn by Wyndham Winona

Days Inn by Wyndham Winona
2.0 star property
Winona
7.8 out of 10, Good, (1,009 reviews)
Wake up to free breakfast at this business-friendly Winona hotel, where a 24-hour fitness center keeps you energized. Just minutes from Remlinger Muscle Cars, enjoy clean rooms, helpful staff, and convenient parking near Mississippi River attractions.
The price is CNY483
CNY539 total
includes taxes & fees
Jun 18 - Jun 19
Days Inn by Wyndham Winona
Exterior

Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG
2.5 star property
Rochester
8.8 out of 10, Excellent, (1,010 reviews)
Relax at this Rochester hotel just minutes from Mayo Clinic. Wake up to a free hot breakfast, unwind in the indoor pool, or keep up your routine at the fitness center. Clean rooms with fridges and microwaves offer comfort after hospital visits.
The price is CNY676
CNY779 total
includes taxes & fees
Jun 21 - Jun 22
Holiday Inn Express Rochester South - Mayo Area by IHG
Restaurant

Hampton Inn & Suites Rochester-North

Hampton Inn & Suites Rochester-North
2.5 star property
Rochester
9.2 out of 10, Wonderful, (1,016 reviews)
Just a short drive from Mayo Clinic, this welcoming hotel offers a refreshing indoor pool and soothing hot tub. Guests love the complimentary breakfast, free WiFi, and convenient parking. The helpful staff and 24-hour fitness center ensure a comfortable stay near Northern Hills Golf Course.
The price is CNY715
CNY824 total
includes taxes & fees
Jul 5 - Jul 6
Hampton Inn & Suites Rochester-North
Lobby lounge

Fairfield Inn & Suites by Marriott Winona

Fairfield Inn & Suites by Marriott Winona
3.0 star property
Winona
9.4 out of 10, Exceptional, (378 reviews)
Just 5 minutes from Mississippi River, this Winona hotel offers a refreshing indoor pool and 24-hour fitness center. Free breakfast, WiFi, and parking enhance your stay near Sugar Loaf Trailhead, with La Crosse airport 28 minutes away.
The price is CNY907
CNY1,012 total
includes taxes & fees
Jul 5 - Jul 6
Fairfield Inn & Suites by Marriott Winona
Indoor pool, open 9:00 AM to 10:00 PM, pool umbrellas, sun loungers

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 star property
Rochester
8.2 out of 10, Very Good, (945 reviews)
Minutes from Mayo Clinic and St. Mary's Campus, this hotel offers free breakfast, parking, and WiFi. Enjoy a swim in the indoor pool, unwind in the hot tub, or grab American cuisine at Wildwood Sports Bar. Nearby restaurants, shops, and attractions await.
The price is CNY536
CNY617 total
includes taxes & fees
Jun 18 - Jun 19
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Indoor pool

Express Suites Riverport Inn & Suites

Express Suites Riverport Inn & Suites
3.0 star property
Winona
8.6 out of 10, Excellent, (1,007 reviews)
This peaceful Winona hotel near Sugar Loaf Trailhead offers an indoor pool and 24-hour fitness center. Grab a meal at Brewski's Pub and enjoy free breakfast. Rooms include fridges and microwaves for added convenience.
The price is CNY730
CNY815 total
includes taxes & fees
Jun 16 - Jun 17
Express Suites Riverport Inn & Suites
Exterior

Staybridge Suites Rochester - Commerce Dr NW by IHG

Staybridge Suites Rochester - Commerce Dr NW by IHG
3.0 star property
Rochester
8.8 out of 10, Excellent, (539 reviews)
Feel at home in this Rochester hotel where complimentary breakfast fuels your day. The indoor pool offers year-round relaxation after visiting Mayo Clinic, just a 10-minute drive away. Clean rooms and helpful staff create a comfortable stay near Badger Ridge Park.
The price is CNY798
CNY919 total
includes taxes & fees
Jun 21 - Jun 22
Staybridge Suites Rochester - Commerce Dr NW by IHG
Front of property

Stone Mill Hotel & Suites

Stone Mill Hotel & Suites
3.0 star property
Lanesboro
9.2 out of 10, Wonderful, (685 reviews)
Nestled alongside a scenic golf course, this charming hotel offers complimentary breakfast, WiFi, and parking. Outdoor enthusiasts can explore nearby hiking trails, kayaking spots, and seasonal skiing, while cultural attractions and the praised staff enhance your countryside escape.
The price is CNY710
CNY762 total
includes taxes & fees
Jun 21 - Jun 22
Stone Mill Hotel & Suites
Exterior

Green Gables Inn

Green Gables Inn
2.0 star property
Lanesboro
9.4 out of 10, Exceptional, (94 reviews)
Nestled in Lanesboro with free continental breakfast served each morning, this welcoming inn offers complimentary WiFi and parking. Discover nearby Root River and Sylvan Park during your stay, with convenient access for outdoor adventures.
The price is CNY783
CNY841 total
includes taxes & fees
Jun 23 - Jun 24
Green Gables Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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When is the best time to visit St. Charles?

Our prices for hotels in St. Charles are cheapest in March
Price trends for hotels in St. Charles
Pricing is based on two traveler single night rates
View properties in June
Currently viewing crowd sizes and weather for June.
Typical weather for St. Charles
June
High 24°C / low 15°C. Sunny most days.
View properties in June
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June, no crowd data, average high temperature 24 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
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26°
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July, no crowd data, average high temperature 26 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
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August, no crowd data, average high temperature 26 degrees Celsius, average low temperature 16 degrees Celsius. Sunny most days.
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22°
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September, no crowd data, average high temperature 22 degrees Celsius, average low temperature 12 degrees Celsius. Sunny most days.
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October, no crowd data, average high temperature 13 degrees Celsius, average low temperature 5 degrees Celsius. Partly sunny.
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November, no crowd data, average high temperature 5 degrees Celsius, average low temperature -2 degrees Celsius. Partly sunny.
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December, no crowd data, average high temperature -2 degrees Celsius, average low temperature -9 degrees Celsius. Snow likely.
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January, no crowd data, average high temperature -6 degrees Celsius, average low temperature -13 degrees Celsius. Snow likely.
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February, no crowd data, average high temperature -4 degrees Celsius, average low temperature -13 degrees Celsius. Snow likely.
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March, no crowd data, average high temperature 5 degrees Celsius, average low temperature -4 degrees Celsius. Snow likely.
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11°
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April, no crowd data, average high temperature 11 degrees Celsius, average low temperature 2 degrees Celsius. Cloudy most days.
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18°
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May, no crowd data, average high temperature 18 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
9°
Monthly weather averages (˚C)

Learn more about St. Charles

St. Charles is well-known for its attractions such as Whitewater State Park and Whitewater River.

See all hotels in St. Charles
St. Charles is a rural Community in South East Minnesota

Check out reviews of St. Charles hotels guests love

Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

8/10 Good
"Excellent stay overall. Breakfast was always great. Front desk staff amazingly helpful. Our only concern was housekeeping was a little disappointing. We had to request clean towels after day 3 and then requested a trash pickup and clean towels again on day 7. We were told there would be a “complete refresh” on day 7, but only had clean towels dropped off."
Robert 9-night trip
Posted 2 hours ago
Hyatt House Rochester/Mayo Clinic Area

Frequently asked questions

How much does a hotel room cost in St. Charles?
You can discover great hotels in St. Charles from CNY492 with properties to suit all budgets and needs. If you're after an affordable hotel in St. Charles that meets all of your requirements, set your filters and then sort the results by "Price: low to high".
How can I find deals and earn rewards at St. Charles hotels?
Discover great deals on St. Charles hotel stays with Hotels.com. Take a look at hotel prices mid-week or during the low season as to find those off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on St. Charles hotels.
Can I book St. Charles hotels with free cancellation?
In order to book a refundable St. Charles hotel, simply filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
What accommodations do travelers recommend in St. Charles?
White Valley Motel is an accommodation that is popular with guests.
Can I book refundable accommodations in St. Charles?
If you need the flexibility to change your plans to St. Charles, most properties provide refundable* bookable rates. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in St. Charles be like during my vacation?
July and August are typically the warmest months in St. Charles when the average temp is 67°F. January and February are the coldest months when the average temperature is 22°F. June and May are the months with the most rain.
Why should I book my St. Charles accommodation with Hotels.com?
There are plenty of reasons to book your St. Charles travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.