Hotels in Des Peres

Q: What hotels do travelers like in Des Peres?

Guests like Clayton Plaza Hotel & Extended Stay , Best Western St. Louis-Kirkwood Route 66 and Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham .

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Dates

April 2026

12

May 2026

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Where to stay in Des Peres?

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Fenton

Central Fenton stay with both indoor and outdoor pools for year-round swimming.

CNY704 total

includes taxes & fees

Apr 13 - Apr 14

Drury Inn & Suites St. Louis Arnold

Arnold

Splashworthy stay with both indoor and outdoor pools for year-round enjoyment.

CNY995 total

includes taxes & fees

Apr 19 - Apr 20

The Principal Hotel

Columbia

Contemporary hotel in Columbia with restaurant and fitness center near Triple Lakes Golf Course.

CNY855 total

includes taxes & fees

Apr 13 - Apr 14

Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free cribs/infant beds

Wingate by Wyndham St. Louis/Fenton Route 66

Fenton

Quiet retreat near restaurants with an inviting outdoor pool and free daily perks.

CNY670 total

includes taxes & fees

Apr 13 - Apr 14

Premium bedding, desk, iron/ironing board, free WiFi

Sleep Inn & Suites O'Fallon MO - Technology Drive

O'Fallon

Enjoy a quiet stay in O'Fallon with indoor swimming and fitness amenities.

CNY661 total

includes taxes & fees

Apr 13 - Apr 14

Comfort Suites St Charles - St Louis

St. Charles

Riverside comfort with easy casino access and complimentary breakfast each morning.

CNY694 total

includes taxes & fees

May 3 - May 4

Best Western Plus Fenton

Fenton

CNY782 total

includes taxes & fees

Apr 15 - Apr 16

The Wildwood Hotel

Wildwood

Comfortable getaway in Wildwood with an indoor pool and free breakfast.

CNY702 total

includes taxes & fees

Apr 13 - Apr 14

Hampton Inn St. Charles St. Peters

St. Charles

Serene pool and fitness amenities near Ameristar Casino in convenient St. Charles.

CNY895 total

includes taxes & fees

Apr 19 - Apr 20

Pear Tree Inn St. Louis Arnold

Arnold

Stay near shopping and restaurants with a peaceful retreat in Arnold.

CNY710 total

includes taxes & fees

Apr 19 - Apr 20

5 restaurants, breakfast, lunch, dinner served; American cuisine

River City Casino & Hotel

St. Louis

Casino retreat just minutes from St. Louis Union Station with 5 restaurants and nightclub.

CNY958 total

includes taxes & fees

Apr 14 - Apr 15

Best Western St. Louis-Kirkwood Route 66

Kirkwood

Route 66 hotel with a seasonal pool near Forest Park and dining options.

CNY735 total

includes taxes & fees

Apr 19 - Apr 20

Drury Inn & Suites Southwest St. Louis

Valley Park

Splash into comfort at Valley Park with indoor and outdoor pools for year-round fun.

CNY887 total

includes taxes & fees

Apr 26 - Apr 27

Premium bedding, desk, iron/ironing board, free cribs/infant beds

Super 8 by Wyndham St Charles

St. Charles

Peaceful highway oasis with free continental breakfast and casino access nearby.

CNY660 total

includes taxes & fees

Apr 26 - Apr 27

Wingate by Wyndham St. Louis Airport

St. Ann

Peaceful airport retreat with free shuttle, pool, and 24-hour fitness center.

CNY876 total

includes taxes & fees

Apr 13 - Apr 14

Holiday Inn Express & Suites St Peters by IHG

St. Peters

Rest and recharge in suburban St. Peters with an indoor pool and complimentary perks.

CNY905 total

includes taxes & fees

Apr 19 - Apr 20

Drury Plaza Hotel St. Louis Chesterfield

Chesterfield

Experience comfort in Chesterfield with dual pools and complimentary breakfast daily.

CNY1,077 total

includes taxes & fees

Apr 16 - Apr 17

Motel 6 Hazelwood, MO

Hazelwood

Stay close to Hollywood Casino in this quiet motel with free parking and WiFi.

CNY526 total

includes taxes & fees

Apr 13 - Apr 14

The West End

Central West End

Chic St. Louis hotel just minutes from Union Station and the Fox Theater.

CNY837 total

includes taxes & fees

Apr 13 - Apr 14

Drury Inn & Suites St. Louis Airport

Edmundson

A peaceful oasis just steps from your flight, with a refreshing pool to unwind in.

CNY921 total

includes taxes & fees

Apr 19 - Apr 20

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Go beyond your typical stay in Des Peres

Family friendly

Pet friendly

Top landmarks in Des Peres

Museum of Transportation

2.5/5 (2 reviews)

Museum of Transportation is 2.5 mi (4 km) from central Des Peres, why not stop by during your stay. If you want to experience more of the culture Des Peres has to offer, head to Kirkwood Park, Magic House - St. Louis Children's Museum, and SSM Health St. Clare Hospital - Fenton.

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Sugar Creek Park

Sugar Creek Park is worth a visit, located 1.8 mi (2.9 km) from central Des Peres. Our travelers also like the museums in the area— your cultural tour starts here.

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Learn more about Des Peres

St. Louis Zoo, St. Louis Union Station, and Enterprise Center are some of the top attractions around Des Peres.

See all hotels in Des Peres

Osage Beach Landmark Buildings in the Historic District on the Main Street near the Lake of the Ozarks in Camden and Miller Counties in Missouri, USA

Check out reviews of Des Peres hotels guests love

Clayton Plaza Hotel & Extended Stay

10/10 Excellent

"Everything was wonderful "

Frequently asked questions

How much does a hotel room cost in Des Peres?

You can choose a great hotel in Des Peres from CNY526 with properties to suit all budgets and needs. If you're after an affordable hotel in Des Peres that meets all of your requirements, set your filters and then sort the results by "Price: low to high".

How can I find deals and earn rewards at Des Peres hotels?

Discover great deals on Des Peres hotel stays with Hotels.com. You can also look at hotel prices mid-week or during the low season to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Des Peres hotels.

Can I book Des Peres hotels with free cancellation?

It's easy to book a refundable Des Peres hotel on Hotels.com. Simply filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

What are some popular hotels in central Des Peres?

For hotels in central Des Peres, check out Courtyard by Marriott St. Louis Brentwood and Hilton St. Louis Frontenac. Travelers love Courtyard by Marriott St. Louis Brentwood for its location, as well as the restaurant, bar/lounge and coffee shop/cafe this hotel offers. Hilton St. Louis Frontenac is another popular central hotel with a seasonal outdoor pool, a restaurant and a bar/lounge. Clayton and Creve Coeur are some of the most central neighborhoods for your Des Peres vacation.

What hotels do travelers like in Des Peres?

Guests like Clayton Plaza Hotel & Extended Stay, Best Western St. Louis-Kirkwood Route 66 and Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham.

Can I book refundable hotels in Des Peres?

If you need the flexibility to change your plans to Des Peres, most accommodations offer refundable* rates you can book. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Des Peres be like during my trip?

The warmest months in Des Peres are usually July and August with an average temp of 76°F. January and February are the chilliest months when the average temp is 37°F. The rainiest months are May and April.

Why should I book my Des Peres accommodation with Hotels.com?

There are plenty of reasons to book your Des Peres travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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