Hotels in Big Pine Key

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Where to stay in Big Pine Key?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top neighborhoods in Big Pine Key

Whispering Pines map

Whispering Pines

The Whispering Pines neighborhood has lots to see including Calusa Beach and Bahia Honda State Park.

Sands map

Sands

Big Pine Key's Sands neighborhood offers attractions including Coupon Bight Aquatic Preserve.

Long Beach Estates map

Long Beach Estates

The Long Beach Estates neighborhood offers attractions such as Florida Keys Beaches and Coupon Bight Aquatic Preserve.

Eden Pines map

Eden Pines

Big Pine Key's Eden Pines neighborhood offers attractions including Blue Hole.

Pine Channel Estates map

Pine Channel Estates

The Pine Channel Estates neighborhood offers attractions such as Calusa Beach and Bahia Honda State Park.

Top landmarks in Big Pine Key

Learn more about Big Pine Key

Kayak through mangrove tunnels, spotting Key deer and colorful fish in crystal-clear waters. Snorkel the Looe Key reef or cast a line for tarpon, all while savoring laid-back island vibes.

Big Pine Key featuring a river or creek, a bay or harbor and general coastal views

Check out reviews of Big Pine Key hotels guests love

Frequently asked questions

What hotels do travelers recommend in Big Pine Key?
Sunshine Key RV Resort & Marina is a property that our guests really like.
Can I book a refundable hotel in Big Pine Key?
If you want the flexibility to change your plans to Big Pine Key, most properties offer refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Big Pine Key if I want a vacation home instead of a hotel?
If you want a good alternative to a hotel, look over our selection of 144 vacation homes. In addition, you can choose from 6 apartments.
What will the weather in Big Pine Key be like during my vacation?
Big Pine Key is a great place to visit any time of year with an average temperature of 72°F during the coldest months.
Why should I book my Big Pine Key accommodation with Hotels.com?
There are lots of reasons to book your Big Pine Key trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.