Hotels in DeSoto

Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices

Check prices for these dates

This weekend
Next weekend

Where to stay in DeSoto?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
trending_down

Our prices for DeSoto are cheapest in December

See average prices for all months
Price trends for hotels in DeSoto
Pricing is based on two traveler single night rates
View properties in August

Month selector

Top landmarks in DeSoto

Learn more about DeSoto

Explore the lush greenery of Moseley Park, where you can picnic or fish in the serene pond. Catch a live performance at the Corner Theatre or browse local art at the DeSoto Art League gallery.

Check out reviews of DeSoto hotels guests love

Frequently asked questions

What accommodations do travelers like in DeSoto?
Can I book a refundable hotel in DeSoto?
If you want the flexibility to change your travel plans to DeSoto, most accommodations offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where can I stay in DeSoto if I want a vacation rental instead of a hotel?
If you want to find a good alternative to a hotel, look over our selection of 25 vacation homes.
What will the weather in DeSoto be like during my trip?
August and July are typically the warmest months in DeSoto when the average temp is 84°F. January and February are the coldest months when the average temperature is 51°F. May and October are the months with the most rain.
Why should I book my DeSoto hotel through Hotels.com?
There are lots of reasons to book your DeSoto trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.