Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Portsmouth on Hotels.com. These Portsmouth hotels consistently deliver on quality, location and traveler experience. Last updated on .
Hotels in Portsmouth
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Sep 11 - Sep 13Where to stay in Portsmouth?
Holiday Inn Portsmouth Downtown by IHG
Holiday Inn Portsmouth Downtown by IHGPortsmouth
CNY873
CNY972 total
includes taxes & fees
Sep 20 - Sep 21
Super 8 by Wyndham Portsmouth
Super 8 by Wyndham PortsmouthPortsmouth
CNY435
CNY484 total
includes taxes & fees
Sep 7 - Sep 8
Quality Inn & Suites Portsmouth
Quality Inn & Suites PortsmouthPortsmouth
CNY453
CNY504 total
includes taxes & fees
Sep 27 - Sep 28
Red Roof Inn Wheelersburg
Red Roof Inn WheelersburgWheelersburg
CNY544
CNY605 total
includes taxes & fees
Sep 20 - Sep 21
Quality Inn Wheelersburg
Quality Inn WheelersburgWheelersburg
CNY639
CNY711 total
includes taxes & fees
Sep 7 - Sep 8
Greenbo Lake State Resort Park
Greenbo Lake State Resort ParkGreenup
CNY483
CNY533 total
includes taxes & fees
Sep 6 - Sep 7
Fairfield Inn & Suites By Marriott Ashland
Fairfield Inn & Suites By Marriott AshlandAshland
CNY689
CNY782 total
includes taxes & fees
Sep 13 - Sep 14
Holiday Inn Express & Suites Ironton by IHG
Holiday Inn Express & Suites Ironton by IHGIronton
CNY766
CNY867 total
includes taxes & fees
Oct 4 - Oct 5
TownePlace Suites by Marriott Ironton
TownePlace Suites by Marriott IrontonIronton
CNY840
CNY951 total
includes taxes & fees
Oct 4 - Oct 5
Comfort Inn Piketon near Fairgrounds
Comfort Inn Piketon near FairgroundsPiketon
CNY689
CNY781 total
includes taxes & fees
Sep 13 - Sep 14
Best Western River Cities
Best Western River CitiesRussell
CNY771
CNY874 total
includes taxes & fees
Sep 20 - Sep 21
Days Inn by Wyndham Grayson
Days Inn by Wyndham GraysonGrayson
CNY598
CNY659 total
includes taxes & fees
Sep 6 - Sep 7
Delta Hotels by Marriott Ashland Downtown
Delta Hotels by Marriott Ashland DowntownAshland
CNY954
CNY1,112 total
includes taxes & fees
Sep 13 - Sep 14
SureStay by Best Western Grayson
SureStay by Best Western GraysonGrayson
CNY668
CNY758 total
includes taxes & fees
Sep 6 - Sep 7
Super 8 by Wyndham Grayson
Super 8 by Wyndham GraysonGrayson
CNY463
CNY525 total
includes taxes & fees
Sep 14 - Sep 15
Red Roof Inn Jackson, OH
Red Roof Inn Jackson, OHJackson
CNY593
CNY689 total
includes taxes & fees
Sep 27 - Sep 28
Ramada by Wyndham Catlettsburg/Ashland
Ramada by Wyndham Catlettsburg/AshlandCatlettsburg
CNY680
CNY771 total
includes taxes & fees
Sep 20 - Sep 21
Holiday Inn Express & Suites Ashland by IHG
Holiday Inn Express & Suites Ashland by IHGAshland
CNY685
CNY777 total
includes taxes & fees
Oct 4 - Oct 5
Quality Inn Ashland
Quality Inn AshlandAshland
CNY665
CNY775 total
includes taxes & fees
Sep 5 - Sep 6
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We have 6 left at
Quality Inn & Suites PortsmouthCNY564
per night
CNY628 total
includes taxes & fees
We have 2 left at
Super 8 by Wyndham PortsmouthCNY635
per night
CNY706 total
includes taxes & fees
CNY638
per night
CNY710 total
includes taxes & fees
Sign in for extra savings
We have 1 left at
Holiday Inn Portsmouth Downtown by IHGCNY1,639
per night
CNY1,824 total
includes taxes & fees
We have 5 left at
Quality Inn & Suites PortsmouthCNY564
per night
CNY628 total
includes taxes & fees
We have 1 left at
Super 8 by Wyndham PortsmouthCNY635
per night
CNY706 total
includes taxes & fees
CNY638
per night
CNY710 total
includes taxes & fees
Sign in for extra savings
We have 1 left at
Holiday Inn Portsmouth Downtown by IHGCNY1,706
per night
CNY1,898 total
includes taxes & fees
We have 1 left at
Royal InnCNY453
per night
CNY504 total
includes taxes & fees
CNY867
per night
CNY964 total
includes taxes & fees
CNY1,209
per night
CNY2,691 total
includes taxes & fees
We have 5 left at
Super 8 by Wyndham PortsmouthCNY680
per night
CNY1,512 total
includes taxes & fees
We have 3 left at
Quality Inn & Suites PortsmouthCNY681
per night
CNY1,514 total
includes taxes & fees
CNY638
per night
CNY1,420 total
includes taxes & fees
Sign in for extra savings
We have 1 left at
Royal InnCNY453
per night
CNY1,009 total
includes taxes & fees
We have 8 left at
Quality Inn WheelersburgCNY720
per night
CNY1,601 total
includes taxes & fees
Check out pet-friendly hotels in Portsmouth
CNY873
CNY972 total
includes taxes & fees
Sep 20 - Sep 21
CNY435
CNY484 total
includes taxes & fees
Sep 7 - Sep 8
CNY453
CNY504 total
includes taxes & fees
Sep 27 - Sep 28
CNY544
CNY605 total
includes taxes & fees
Sep 20 - Sep 21
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all propertiesGo beyond your typical stay in Portsmouth
Pet friendly
Family friendly
Our prices for hotels in Portsmouth are cheapest in July
Our prices for hotels in Portsmouth are cheapest in July
Price trends for hotels in Portsmouth
Pricing is based on two traveler single night rates
Top landmarks in Portsmouth
Boneyfiddle Commercial District
Boneyfiddle Commercial District is just one of the landmarks located 0.4 mi (0.6 km) from central Portsmouth, so you might want to stop by for a few pics during your trip.
Portsmouth Floodwall Mural
Portsmouth Floodwall Mural is 0.3 mi (0.6 km) from central Portsmouth, why not stop by during your stay. If you have fun at Portsmouth Floodwall Mural, you'll love Vern Riffe Center for the Arts, located nearby.
Mound Park
Mound Park is worth a visit, located 1.4 mi (2.2 km) from central Portsmouth.
Vern Riffe Center for the Arts
Vern Riffe Center for the Arts is in the heart of Portsmouth, so why not stop by during your stay. If you have fun at Vern Riffe Center for the Arts, you'll love Portsmouth Floodwall Mural, located nearby.
Portsmouth and related destinations
Wander along the 2,200-foot floodwall where Robert Dafford's murals transform concrete into a vivid historical canvas. The Southern Ohio Museum houses local artifacts that tell stories more fascinating than fiction. Boneyfiddle District rewards visitors with antique shops where proprietors share tales as valuable as their merchandise. The Vern Riffe Center hosts performances that draw regional audiences. Ohio River views provide a peaceful backdrop, particularly at sunset when the water turns to liquid gold. Shawnee State Park offers forest trails where city noise fades away. University students add youthful energy to this riverside town where Appalachian heritage meets small-city sophistication. Earl Thomas Conley Riverside Park provides picnic spots with views that explain why settlers decided to stay.
See all hotels in Portsmouth
Check out reviews of Portsmouth hotels guests love
Fairfield Inn & Suites By Marriott Ashland
10/10 Excellent
"ggreat place to unwind. water pressure great for showers"
Days Inn by Wyndham Grayson
10/10 Excellent
"This was one of the best inns I've stayed at. From the friendliness of the desk clerk (😉 Kathy Lynn), to the cleanliness of the room (shout out to Kristi!), to the comfort of the beds, and the nice selection of breakfast items, this Days Inn is a winner in my book. It has great proximity to the interstate, a win-win when traveling. The property is well maintained, both inside and out. The owner's choice of furnishings and fixtures is top notch for this type of establishment. I will definitely be back!"
Greenbo Lake State Resort Park
10/10 Excellent
"The lodge at Greenbo was AMAZING. The area was peaceful, the rooms were spacious, well accented and comfortable. To top it off there was free, HOT breakfast and the price was extremely reasonable. Looking forward to staying here again."
Days Inn by Wyndham Ashland
10/10 Excellent
"Staff was AMAZING, room was clean, properly is outdated on inside. Safety, distance, & pet friendly was a HUGE plus!"
Quality Inn & Suites Portsmouth
8/10 Good
"Would return and plan on doing so"
Holiday Inn Express & Suites Ironton by IHG
10/10 Excellent
"Fast check in, nice staff, good location, super clean"
SureStay by Best Western Grayson
10/10 Excellent
"Best place to stay in the area"
TownePlace Suites by Marriott Ironton
8/10 Good
"Overall, my stay was pleasant. The hotel was clean, quiet, and provided all of the amenities I needed. The staff was also very friendly and helpful, and I was pleased with my stay in general. However, I did have one very concerning experience that I feel should be mentioned. At approximately 6:30 in the morning, someone attempted to enter my room using a key card. Thankfully, I had the door latch engaged, so they were unable to enter. When I asked the front desk about the situation, I was told that it was not housekeeping, although it could have been security staff. That means someone apparently had a key card that could access my room, which is a serious security concern. While everything else about my stay was fine, this incident left me feeling very uneasy."
Delta Hotels by Marriott Ashland Downtown
10/10 Excellent
"Clean too"