Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Santa Cruz on Hotels.com. These Santa Cruz hotels consistently deliver on comfort, location and traveler experience. Last updated on .
Hotels in Santa Cruz
Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices
Check prices for these dates
Tonight
Aug 27 - Aug 28Tomorrow
Aug 28 - Aug 29This weekend
Aug 28 - Aug 30Next weekend
Sep 4 - Sep 6Where to stay in Santa Cruz?
Hotel Cava Colchagua
Hotel Cava ColchaguaSanta Cruz
CNY1,200
CNY1,200 total
Sep 20 - Sep 21
Hotel Boutique Vendimia Premium
Hotel Boutique Vendimia PremiumSanta Cruz
CNY687
CNY687 total
Sep 20 - Sep 21
Hotel Boutique Grand Cru
Hotel Boutique Grand CruSanta Cruz
CNY656
CNY656 total
Aug 31 - Sep 1
Hotel Vendimia Parador
Hotel Vendimia ParadorSanta Cruz
CNY576
CNY576 total
Aug 29 - Aug 30
Colchagua Tiny Lodge
Colchagua Tiny LodgeSanta Cruz
CNY1,034
CNY1,034 total
Aug 29 - Aug 30
Noi Blend Colchagua
Noi Blend ColchaguaPalmilla
CNY1,124
CNY1,124 total
Sep 6 - Sep 7
Hotel Viña La Playa
Hotel Viña La PlayaPeralillo
CNY1,815
CNY1,815 total
Sep 14 - Sep 15
Hacienda Histórica Marchigüe
Hacienda Histórica MarchigüeMarchihue
CNY1,331
CNY1,331 total
Sep 23 - Sep 24
Get last-minute hotel deals in Santa Cruz and save more
Sign in to unlock great savings.
We have 3 left at
Hotel Boutique Vendimia PremiumCNY769
per night
CNY1,539 total
CNY294 off
Hotel Cava ColchaguaCNY1,002
per night
CNY2,004 total
We have 3 left at
Hotel Vendimia ParadorCNY576
per night
CNY1,152 total
We have 1 left at
La Perla HotelCNY579
per night
CNY1,159 total
We have 1 left at
Colchagua Tiny LodgeCNY1,028
per night
CNY2,057 total
We have 2 left at
Hotel Boutique Grand CruCNY938
per night
CNY1,876 total
We have 3 left at
Hotel Boutique Vendimia PremiumCNY801
per night
CNY1,603 total
We have 1 left at
La Perla HotelCNY550
per night
CNY1,099 total
We have 1 left at
Hotel Vendimia ParadorCNY892
per night
CNY1,784 total
We have 2 left at
Hotel Boutique Grand CruCNY938
per night
CNY1,876 total
We have 3 left at
Hotel Boutique Vendimia PremiumCNY748
per night
CNY748 total
We have 2 left at
Hotel Vendimia ParadorCNY706
per night
CNY706 total
We have 1 left at
Hotel Boutique Grand CruCNY653
per night
CNY653 total
We have 6 left at
Colchagua Tiny LodgeCNY1,028
per night
CNY1,028 total
CNY177 off
Hotel Cava ColchaguaCNY1,591
per night
CNY1,591 total
You can also stay at hotels with a pool in Santa Cruz
CNY878
CNY878 total
Sep 12 - Sep 13
CNY687
CNY687 total
Sep 20 - Sep 21
CNY656
CNY656 total
Aug 31 - Sep 1
CNY576
CNY576 total
Aug 31 - Sep 1
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all propertiesGo beyond your typical stay in Santa Cruz
Our prices for hotels in Santa Cruz are cheapest in July
Our prices for hotels in Santa Cruz are cheapest in July
Price trends for hotels in Santa Cruz
Pricing is based on two traveler single night rates
Top landmarks in Santa Cruz
Lapostolle Clos Apalta Winery
9.4/10 (21 reviews)
Travelers might want a tour of Lapostolle Clos Apalta Winery, just one of the places to visit, and located 5.3 mi (8.5 km) from central Santa Cruz.
Laura Hartwig Winery
9.0/10 (17 reviews)
Travelers might want a tour of Laura Hartwig Winery, just one of the places to visit, and located 0.8 mi (1.3 km) from central Santa Cruz.
Colchagua Campo y Vino
9.4/10 (3 reviews)
Colchagua Campo y Vino is 1.4 mi (2.2 km) from central Santa Cruz, why not stop by during your stay.
Casino Colchagua
8.0/10 (6 reviews)
Casino Colchagua is 1.4 mi (2.2 km) from central Santa Cruz, why not stop by during your stay.
Bodega Viña Viu Manent
10.0/10 (1 review)
Travelers might want a tour of Bodega Viña Viu Manent, just one of the places to visit, and located 3.4 mi (5.4 km) from central Santa Cruz.
Museo de Colchagua
9.6/10 (24 reviews)
The center of Santa Cruz is home to cultural attractions like Museo de Colchagua, so you might want to stop by during your stay. If you want to experience more of the culture Santa Cruz has to offer, head to Colchagua Campo y Vino, Casino Colchagua, and Laura Hartwig Winery.
Plaza de Armas
8.2/10 (34 reviews)
If you're planning a bit of sightseeing during your trip, head to Plaza de Armas— just one of the monuments in central Santa Cruz.
Learn more about Santa Cruz
Notable for its wineries, Santa Cruz features attractions such as Laura Hartwig Winery and Colchagua Campo y Vino. This relaxing city has something for everyone including restaurants as well as sights like Casino Colchagua and Lapostolle Clos Apalta Winery. All are within a rural setting.
See all hotels in Santa Cruz
Check out reviews of Santa Cruz hotels guests love
TerraViña
10/10 Excellent
"The staff were very friendly and knowledgeable of the local restaurants and wineries. The room has a balcony which was fabulous. Properly was well maintained and beautiful. Definitely would come back to this property."
Hotel Cava Colchagua
10/10 Excellent
"Excelente y original experiencia boutique Una propuesta realmente innovadora. Se trata de un hotel boutique hermoso cuyas habitaciones están acondicionadas dentro de barricas de roble, muy bien adaptadas y acogedoras. Como sugerencia de mejora, creo que a las habitaciones más grandes les vendría muy bien incluir un perchero y una pequeña mesa con dos sillas para mayor comodidad. Asimismo, en el baño eché de menos una mejor iluminación en el área del espejo. Por lo demás, todo fenomenal. El personal es sumamente amable y siempre está atento a cualquier necesidad. ¡Regresaría sin dudarlo!"
Hotel Vendimia Parador
10/10 Excellent
" "I had a wonderful experience at this hotel. The location is fantastic—central and convenient to everything I wanted to see. The room was spotless and well-maintained, which I really appreciated. But what truly sets this place apart is the staff. From the front desk to the housekeeping team, everyone was genuinely warm, helpful, and went out of their way to be friendly. It made all the difference. I would absolutely stay here again." "
Hotel Boutique Grand Cru
10/10 Excellent
"Great breakfast. Super host Juan Luis. Great location. Comfy bed. Spacious loft style rooms "