Photo by Bill Dillard

Hotels in Southeast Missouri

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Check prices for these dates

Tonight
Nov 16 - Nov 17
Tomorrow
Nov 17 - Nov 18
Next weekend
Nov 21 - Nov 23
In two weeks
Nov 28 - Nov 30

Where to stay in Southeast Missouri?

Property amenity
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
3.0 star property
9.4 out of 10, Exceptional, (1003)
The price is CNY681
CNY784 total
includes taxes & fees
Nov 21 - Nov 22
Drury Inn & Suites Sikeston, MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Great weekend hotel deals in Southeast Missouri, MO

Showing deals for:Nov 28 - Nov 30

Image gallery for Tiny Houses of French Village

House | Living area

Tiny Houses of French Village

2.5 star property
French Village
10/10Exceptional (3 reviews)
10% off
Price is CNY1,725
CNY4,150 total
includes taxes & fees
Tiny Houses of French Village

Check out hotels with a hot tub in Southeast Missouri

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Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

3.0 star property
Jackson
9.6 out of 10, Exceptional, (1003)
The price is CNY625
CNY660 total
includes taxes & fees
Nov 17 - Nov 18
Drury Inn & Suites Jackson MO
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You may also like family-friendly hotels in Southeast Missouri

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Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

2.0 star property
Poplar Bluff
7.8 out of 10, Good, (1006)
The price is CNY540
CNY569 total
includes taxes & fees
Nov 17 - Nov 18
Motel 6 Poplar Bluff, MO
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You can also stay at pet-friendly hotels in Southeast Missouri

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Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

3.0 star property
Jackson
9.6 out of 10, Exceptional, (1003)
The price is CNY625
CNY660 total
includes taxes & fees
Nov 17 - Nov 18
Drury Inn & Suites Jackson MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top landmarks in Central United States

Panorama of Academic Hall, Southeast Missouri State University

Southeast Missouri State University

4.4/5 (137 reviews)
If you'd like to get a taste of Cape Girardeau student life, check out Southeast Missouri State University, located 0.9 mi (1.4 km) from central Cape Girardeau.
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A huge granite boulder located in Elephant Rocks State Park
Photo by Pat Long
Open Photo by Pat Long

Elephant Rocks State Park

4.8/5 (52 reviews)
Elephant Rocks State Park is 5.3 mi (8.5 km) from central Ironton, why not stop by during your stay.
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Learn more about Southeast Missouri

Southeast Missouri is well-known for its wineries and riverfront while attractions include Sam A. Baker State Park and K Bridge Recreation Area. This family-friendly city has something for everyone including its university life, restaurants, and sights like Lake Wappapello State Park and Clearwater Lake.

See all hotels in Southeast Missouri
Mini Takes the States 2014 Road Rally Memphis to St.Louis Leg: Moark Regional Railroad Museum HOURS: Saturdays 1 p.m. - 4 p.m. It was not open when I stopped by but there are a few rail cars outside. Poplar has a train rich history. This was a cool little town to stop in and take pictures. Lot's of wall murals for some reason, and some very cool architecture. Worth the stop and be sure and enjoy a lunch at Hayden's Drive-In ! #MTTS2014 #minitakesthestates #go11 #train
Photo by Bill Dillard
Open Photo by Bill Dillard

Check out reviews of Southeast Missouri hotels guests love

The Farmstead Hotel

The Farmstead Hotel

10/10 Excellent
"Clean rooms and really comfortable beds!"
Andrea 1-night trip
Posted 1 day ago
The Farmstead Hotel

Frequently asked questions

Why should I book my Southeast Missouri accommodation with Hotels.com?
There are plenty of reasons to book your Southeast Missouri travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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