Photo by Bill Dillard
Hotels in Southeast Missouri
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Where to stay in Southeast Missouri?
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,006 reviews)
- Quiet escape near Cape Girardeau with an indoor pool for year-round enjoyment.
The price is CNY549
CNY580 total
includes taxes & fees
Apr 13 - Apr 14
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (172 reviews)
- Stay near Fort D Historic Site with a free breakfast and indoor pool.
The price is CNY633
CNY714 total
includes taxes & fees
Apr 16 - Apr 17
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
9.8 out of 10, Exceptional, (57 reviews)
- Rustic cabin getaway in French Village with private patios and kitchen comforts.
The price is CNY578
CNY917 total
includes taxes & fees
Apr 13 - Apr 14
Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
9.6 out of 10, Exceptional, (117 reviews)
- Relax at a modern hotel near Shawnee Forest with a refreshing indoor pool.
The price is CNY667
CNY759 total
includes taxes & fees
Apr 16 - Apr 17
Tiny Houses of French Village
Tiny Houses of French VillageFrench Village
10.0 out of 10, Exceptional, (5 reviews)
- Charming tiny houses welcome you to French Village with picturesque amenities.
The price is CNY457
CNY1,029 total
includes taxes & fees
Apr 13 - Apr 14
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,001 reviews)
- Explore the stunning forest views with free breakfast, indoor pool, and dining options.
The price is CNY683
CNY771 total
includes taxes & fees
May 10 - May 11
Arcadia Academy
Arcadia AcademyArcadia
9.8 out of 10, Exceptional, (11 reviews)
- Charming vineyard retreat with antique flair near historic Arcadia Valley Station.
The price is CNY930
CNY1,009 total
includes taxes & fees
Apr 13 - Apr 14
Lake Wappapello
Lake WappapelloWilliamsville
10.0 out of 10, Exceptional, (1 review)
- Serene lake getaway with cozy cabins and nearby historic attractions.
The price is CNY583
CNY615 total
includes taxes & fees
Apr 22 - Apr 23
Holiday Inn Express & Suites Perryville by IHG
Holiday Inn Express & Suites Perryville by IHGPerryville
9.2 out of 10, Wonderful, (577 reviews)
- Enjoy a refreshing stay with a 24-hour fitness center and indoor pool in Perryville.
The price is CNY690
CNY790 total
includes taxes & fees
Apr 12 - Apr 13
Honeysuckle Inn - Mountain View
Honeysuckle Inn - Mountain ViewMountain View
8.6 out of 10, Excellent, (343 reviews)
- Charming lodge in Ozark Mountain country with hiking trails and free amenities.
The price is CNY652
CNY707 total
includes taxes & fees
Apr 27 - Apr 28
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.4 out of 10, Exceptional, (1,001 reviews)
- Peaceful highway-adjacent retreat with indoor and outdoor pool options.
The price is CNY758
CNY872 total
includes taxes & fees
May 9 - May 10
Super 8 by Wyndham Farmington
Super 8 by Wyndham FarmingtonFarmington
8.0 out of 10, Very Good, (633 reviews)
- Modern rooms near shopping and parks in the heart of Farmington.
The price is CNY408
CNY444 total
includes taxes & fees
May 3 - May 4
Crown Pointe Lodge, BW Signature Collection
Crown Pointe Lodge, BW Signature CollectionFarmington
9.0 out of 10, Wonderful, (604 reviews)
- Lakeside haven with championship golf and warm service at this serene retreat.
The price is CNY691
CNY752 total
includes taxes & fees
May 10 - May 11
The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (544 reviews)
- Try your luck at the casino and savor American cuisine at this Cape Girardeau hotel.
The price is CNY904
CNY1,020 total
includes taxes & fees
Apr 14 - Apr 15
New Orleans Inn Portageville
New Orleans Inn PortagevillePortageville
8.0 out of 10, Very Good, (757 reviews)
- Comfortable motel near Cape Girardeau with free WiFi and helpful 24-hour service.
The price is CNY387
CNY418 total
includes taxes & fees
May 10 - May 11
Drury Inn & Suites Poplar Bluff
Drury Inn & Suites Poplar BluffPoplar Bluff
9.2 out of 10, Wonderful, (1,001 reviews)
- Relax in dual indoor-outdoor pool options in this Poplar Bluff tranquil retreat.
The price is CNY642
CNY725 total
includes taxes & fees
Apr 26 - Apr 27
The Farmstead Hotel
The Farmstead HotelCaruthersville
8.6 out of 10, Excellent, (533 reviews)
- Serene and well-maintained riverfront property with gaming excitement and quiet comfort.
The price is CNY642
CNY730 total
includes taxes & fees
Apr 12 - Apr 13
Baymont Inn and Suites by Wyndham Farmington, MO
Baymont Inn and Suites by Wyndham Farmington, MOFarmington
8.0 out of 10, Very Good, (1,002 reviews)
- Stay in Farmington with easy highway access, close to restaurants and local parks.
The price is CNY406
CNY442 total
includes taxes & fees
Apr 19 - Apr 20
Century Casino & Hotel Caruthersville
Century Casino & Hotel CaruthersvilleCaruthersville
8.6 out of 10, Excellent, (140 reviews)
The price is CNY830
CNY944 total
includes taxes & fees
Apr 10 - Apr 11
Shepherd Mountain Inn
Shepherd Mountain InnIronton
9.2 out of 10, Wonderful, (310 reviews)
- Enjoy a peaceful mountain escape with bar, restaurant, and nearby hiking trails.
The price is CNY741
CNY810 total
includes taxes & fees
Apr 12 - Apr 13
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Showing deals for:Apr 9 - Apr 10
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
9.0 out of 10, Wonderful, (739 reviews)
CNY68 off
The price is CNY609
per night
CNY659 total
includes taxes & fees
Showing deals for:Apr 10 - Apr 11
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
9.0 out of 10, Wonderful, (739 reviews)
CNY81 off
The price is CNY732
per night
CNY792 total
includes taxes & fees
Showing deals for:Apr 17 - Apr 19
10.0 out of 10, Exceptional, (1 review)
The price is CNY1,722
per night
CNY3,641 total
includes taxes & fees
You may also like pet-friendly hotels in Southeast Missouri
8.0 out of 10, Very Good, (1000)
The price is CNY444
CNY468 total
includes taxes & fees
Apr 12 - Apr 13
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Southeast Missouri
Family friendly
Top landmarks in Central United States
Learn more about Southeast Missouri
Southeast Missouri is well-known for its wineries and riverfront while attractions include Sam A. Baker State Park and K Bridge Recreation Area. This family-friendly city has something for everyone including its university life, restaurants, and sights like Lake Wappapello State Park and Clearwater Lake.
Photo by Bill Dillard
Open Photo by Bill Dillard
Check out reviews of Southeast Missouri hotels guests love
Pear Tree Inn Cape Girardeau West
10/10 Excellent
Frequently asked questions
Keep exploring
- Perryville Hotels
- Hotels near Missouri's National Veterans Memorial
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- Hotels with Free Breakfast in Sikeston
- Hotels near St. Francois State Park
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- Hotels near Sikeston Memorial Municipal
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