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Hotels in Melrose

October 2026
5
November 2026

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This weekend
Oct 9 - Oct 11
Next weekend
Oct 16 - Oct 18

Where to stay in Melrose?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Melrose on Hotels.com. These Melrose hotels consistently deliver on quality, location and traveler experience. Last updated on October 5, 2026.
A modern lobby with a reception desk, seating area, and a large window.
A modern dining area with tables and chairs, a kitchen area, and a television mounted on the wall.
A gym with treadmills, stationary bikes, and a weight machine.
A Comfort Suites hotel with a modern design, featuring a prominent crescent moon logo on the facade.

1. Comfort Suites Natchitoches

Comfort Suites Natchitoches
Natchitoches
CNY669
CNY786 total
includes taxes & fees
Nov 1 - Nov 2
Comfort Suites Natchitoches
A Holiday Inn Express & Suites building with a prominent entrance, large windows, and a brick facade.
A modern dining area with multiple tables and chairs, a kitchen area with a counter, and large windows providing natural light.
A hotel reception area with two reception desks, a digital display, a flat-screen TV, and a sign indicating the hotel name.
Room amenity

2. Holiday Inn Express Hotel & Suites Natchitoches by IHG

Holiday Inn Express Hotel & Suites Natchitoches by IHG
Natchitoches
CNY718
CNY836 total
includes taxes & fees
Nov 2 - Nov 3
Holiday Inn Express Hotel & Suites Natchitoches by IHG
A modern lobby with a stone wall, blue seating, a round table, and large windows.
A Fairfield Inn & Suites Marriott hotel with a clear 10'-0" sign, outdoor seating, and a parking lot.
A buffet area with wooden paneling and a mural of wheat.
A corner market with a refrigerated display and shelves stocked with snacks and beverages.

3. Fairfield Inn & Suites Natchitoches

Fairfield Inn & Suites Natchitoches
Natchitoches
CNY621
CNY730 total
includes taxes & fees
Oct 11 - Oct 12
Fairfield Inn & Suites Natchitoches
A modern Hampton Inn hotel with a clear entrance, stone pillars, and a neon sign.
A reception area with a blue wall displaying "WELCOME TO THE CREOLE STATE" and a "Manager On Duty" sign. There are two self-service kiosks and a "Hilton Honors" sign.
A snack display with various chips and a refrigerated section with beverages.
A hotel room with two beds, a central sink, and a wall-mounted lamp.

4. Hampton Inn Natchitoches

Hampton Inn Natchitoches
Natchitoches
CNY638
CNY744 total
includes taxes & fees
Nov 1 - Nov 2
Hampton Inn Natchitoches
A modern dining area with wooden tables and chairs, a flat-screen TV mounted on the wall, and a kitchen area with appliances and a coffee machine.
A hotel room with two beds, a nightstand with a lamp, a headboard, a window with a view, and a framed picture on the wall.
A modern living room with a brick wall, two sofas, a TV, and a small table.
A hotel with a swimming pool, a parking lot, and a building with multiple windows.

5. Best Western Natchitoches Inn

Best Western Natchitoches Inn
Natchitoches
CNY690
CNY804 total
includes taxes & fees
Oct 11 - Oct 12
Best Western Natchitoches Inn
A brick building with a sign reading "Southern Living Hotel Collection."
A bar area with a long counter, multiple bar stools, and pendant lighting. There are wooden cabinets with glass doors and a flat-screen TV mounted on the wall.
A dining area with a table set for four, a painting above the table, and a window with curtains.
A spacious lobby with wooden flooring, a chandelier, and a bench.

6. Chateau Saint Denis Hotel

Chateau Saint Denis Hotel
Downtown Natchitoches
CNY643
CNY911 total
includes taxes & fees
Oct 6 - Oct 7
Chateau Saint Denis Hotel
A spacious room with a large window, a dining table with chairs, and a small balcony with a table and chairs.
A room with a large window overlooking a historic building with a dome.
A covered outdoor patio with brick flooring, metal railings, and outdoor furniture.
A spacious lobby with a grand chandelier, a large Christmas tree, and a vibrant abstract painting on the wall.

7. Church Street Inn

Church Street Inn
Downtown Natchitoches
CNY771
CNY899 total
includes taxes & fees
Oct 11 - Oct 12
Church Street Inn
A hotel room with two beds, each with a patterned bedspread, a nightstand with a lamp, and a large framed picture of a bridge.
A reception area with two red leather chairs, a wall clock, a black speaker, and a plant.
A hotel room with a washing machine, an ice dispenser, and vending machines.
A modern hotel lobby with a reception desk, seating area, and a kitchen counter.

8. Super 8 by Wyndham Natchitoches

Super 8 by Wyndham Natchitoches
Natchitoches
CNY428
CNY498 total
includes taxes & fees
Oct 30 - Oct 31
Super 8 by Wyndham Natchitoches
A hotel with a prominent EconoLodge Inn & Suites sign, featuring a multi-story building with a red and beige color scheme, surrounded by well-maintained landscaping and palm trees.
A hotel room with a bed, a desk with a chair, a TV mounted on the wall, and a window with curtains.
A lobby with a brown leather sofa, a reception desk, and a fire extinguisher.
A hotel room with a bed, a sofa, a desk, and a chair.

9. Econo Lodge Inn & Suites Natchitoches

Econo Lodge Inn & Suites Natchitoches
Natchitoches
CNY596
CNY694 total
includes taxes & fees
Oct 25 - Oct 26
Econo Lodge Inn & Suites Natchitoches
A large, two-story house with a porch and a sign for the Sweet Cane Inn.
A room with a large Christmas tree, a vintage sofa, and a chandelier.
A four-poster bed with a canopy, a chandelier, and a painting on the wall.
A staircase with a wooden handrail and a stained glass window with floral patterns.

10. Sweet Cane Inn

Sweet Cane Inn
Downtown Natchitoches
CNY905
CNY1,028 total
includes taxes & fees
Oct 6 - Oct 7
Sweet Cane Inn
A swimming pool with lounge chairs, a covered seating area, and a fenced deck.
A hotel room with two beds, a nightstand, a lamp, a window with curtains, and a carpeted floor.
A covered picnic area with tables and chairs, a trash can, and a lamp post.
A hotel lobby with a reception desk, a framed picture on the wall, a green mat with the hotel logo, and a trash can.

11. Quality Inn near Parc Natchitoches

Quality Inn near Parc Natchitoches
Natchitoches
CNY524
CNY611 total
includes taxes & fees
Nov 1 - Nov 2
Quality Inn near Parc Natchitoches
A lobby with a patterned armchair, a television mounted on the wall, and a view of the outside through large windows.
A lobby with a reception desk, two patterned armchairs, a tiled floor, and a ceiling with recessed lighting.
A coffee station with a coffee maker, cups, and coffee beans. There are posters on the wall and a vase with flowers.
A neatly made bed with a red and gray blanket, two bedside lamps, and a wooden nightstand with a telephone.

12. Motel 6 Natchitoches, LA

Motel 6 Natchitoches, LA
Natchitoches
CNY362
CNY422 total
includes taxes & fees
Nov 1 - Nov 2
Motel 6 Natchitoches, LA
A hotel room with a bed, a sofa, a small table, and a painting on the wall.
A compact room with a television mounted on the wall, a desk with a lamp, a microwave, and a small seating area with a blue cushion.
A motel with a green roof, multiple balconies, and a swimming pool area with umbrellas.
A hotel with a green roof, a Days Inn sign, and a fenced parking area.

13. Days Inn by Wyndham Natchitoches

Days Inn by Wyndham Natchitoches
Natchitoches
CNY465
CNY541 total
includes taxes & fees
Nov 3 - Nov 4
Days Inn by Wyndham Natchitoches
A wooden entrance with a glass door, a welcome sign, and two potted plants.
A grand chandelier with multiple crystal tiers and a decorative ceiling medallion.
A front porch with a brick pathway leading to a wooden door, white columns, and a hanging American flag.
A spacious living room with a large leather sofa, a chandelier, and a fireplace.

14. Opus House

Opus House
Natchitoches
CNY1,144
CNY1,299 total
includes taxes & fees
Oct 10 - Oct 11
Opus House
View all properties

Go beyond your typical stay in Melrose

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Pool
Pool
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Pet friendly
Pet friendly
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Hot tub
Hot tub
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Family friendly
Family friendly

Top landmarks in Melrose

Melrose Plantation

9.2/10 (45 reviews)
If you're planning a bit of sightseeing during your trip, head to Melrose Plantation— just one of the monuments in central Melrose.
See properties

Check out reviews of Melrose hotels guests love

A spacious room with a large window, a dining table with chairs, and a small balcony with a table and chairs.
A room with a large window overlooking a historic building with a dome.
A covered outdoor patio with brick flooring, metal railings, and outdoor furniture.
A spacious lobby with a grand chandelier, a large Christmas tree, and a vibrant abstract painting on the wall.

Church Street Inn

Church Street Inn
Downtown Natchitoches

10/10 Exceptional

United States
Anonymous traveler
Church Street Inn
A Holiday Inn Express & Suites building with a prominent entrance, large windows, and a brick facade.
A modern dining area with multiple tables and chairs, a kitchen area with a counter, and large windows providing natural light.
A hotel reception area with two reception desks, a digital display, a flat-screen TV, and a sign indicating the hotel name.
Room amenity

Holiday Inn Express Hotel & Suites Natchitoches by IHG

Holiday Inn Express Hotel & Suites Natchitoches by IHG
Natchitoches

10/10 Exceptional

United States
Anonymous traveler
Holiday Inn Express Hotel & Suites Natchitoches by IHG
A modern lobby with a reception desk, seating area, and a large window.
A modern dining area with tables and chairs, a kitchen area, and a television mounted on the wall.
A gym with treadmills, stationary bikes, and a weight machine.
A Comfort Suites hotel with a modern design, featuring a prominent crescent moon logo on the facade.

Comfort Suites Natchitoches

Comfort Suites Natchitoches
Natchitoches

10/10 Exceptional

United States
Robert
Comfort Suites Natchitoches
A large, two-story house with a porch and a sign for the Sweet Cane Inn.
A room with a large Christmas tree, a vintage sofa, and a chandelier.
A four-poster bed with a canopy, a chandelier, and a painting on the wall.
A staircase with a wooden handrail and a stained glass window with floral patterns.

Sweet Cane Inn

Sweet Cane Inn
Downtown Natchitoches

10/10 Exceptional

United States
Anonymous traveler
Sweet Cane Inn
A modern lobby with a stone wall, blue seating, a round table, and large windows.
A Fairfield Inn & Suites Marriott hotel with a clear 10'-0" sign, outdoor seating, and a parking lot.
A buffet area with wooden paneling and a mural of wheat.
A corner market with a refrigerated display and shelves stocked with snacks and beverages.

Fairfield Inn & Suites Natchitoches

Fairfield Inn & Suites Natchitoches
Natchitoches

10/10 Exceptional

United States
Peggy
Fairfield Inn & Suites Natchitoches
A modern Hampton Inn hotel with a clear entrance, stone pillars, and a neon sign.
A reception area with a blue wall displaying "WELCOME TO THE CREOLE STATE" and a "Manager On Duty" sign. There are two self-service kiosks and a "Hilton Honors" sign.
A snack display with various chips and a refrigerated section with beverages.
A hotel room with two beds, a central sink, and a wall-mounted lamp.

Hampton Inn Natchitoches

Hampton Inn Natchitoches
Natchitoches

10/10 Exceptional

United States
Becky
Hampton Inn Natchitoches
A modern dining area with wooden tables and chairs, a flat-screen TV mounted on the wall, and a kitchen area with appliances and a coffee machine.
A hotel room with two beds, a nightstand with a lamp, a headboard, a window with a view, and a framed picture on the wall.
A modern living room with a brick wall, two sofas, a TV, and a small table.
A hotel with a swimming pool, a parking lot, and a building with multiple windows.

Best Western Natchitoches Inn

Best Western Natchitoches Inn
Natchitoches

10/10 Exceptional

United States
Charles
Best Western Natchitoches Inn
A wooden entrance with a glass door, a welcome sign, and two potted plants.
A grand chandelier with multiple crystal tiers and a decorative ceiling medallion.
A front porch with a brick pathway leading to a wooden door, white columns, and a hanging American flag.
A spacious living room with a large leather sofa, a chandelier, and a fireplace.

Opus House

Opus House
Natchitoches

10/10 Exceptional

United States
Misty
Opus House
A hotel room with two beds, each with a patterned bedspread, a nightstand with a lamp, and a large framed picture of a bridge.
A reception area with two red leather chairs, a wall clock, a black speaker, and a plant.
A hotel room with a washing machine, an ice dispenser, and vending machines.
A modern hotel lobby with a reception desk, seating area, and a kitchen counter.

Super 8 by Wyndham Natchitoches

Super 8 by Wyndham Natchitoches
Natchitoches

10/10 Exceptional

United States
Beverly
Super 8 by Wyndham Natchitoches
A hotel with a prominent EconoLodge Inn & Suites sign, featuring a multi-story building with a red and beige color scheme, surrounded by well-maintained landscaping and palm trees.
A hotel room with a bed, a desk with a chair, a TV mounted on the wall, and a window with curtains.
A lobby with a brown leather sofa, a reception desk, and a fire extinguisher.
A hotel room with a bed, a sofa, a desk, and a chair.

Econo Lodge Inn & Suites Natchitoches

Econo Lodge Inn & Suites Natchitoches
Natchitoches

10/10 Exceptional

United States
Randy
Econo Lodge Inn & Suites Natchitoches
A swimming pool with lounge chairs, a covered seating area, and a fenced deck.
A hotel room with two beds, a nightstand, a lamp, a window with curtains, and a carpeted floor.
A covered picnic area with tables and chairs, a trash can, and a lamp post.
A hotel lobby with a reception desk, a framed picture on the wall, a green mat with the hotel logo, and a trash can.

Quality Inn near Parc Natchitoches

Quality Inn near Parc Natchitoches
Natchitoches

10/10 Exceptional

United States
Michelle
Quality Inn near Parc Natchitoches

Frequently Asked Questions

How much does a hotel room cost in Melrose?

You can find top hotels in Melrose from CNY362 with options to suit your budget and needs. To find an affordable hotel in Melrose that meets all of your requirements, just apply filters on Hotels.com and sort hotels by "Price: low to high".

How can I find deals and earn rewards at Melrose hotels?

Discover great deals on Melrose hotel stays with Hotels.com. You can also look at hotel prices mid-week or during the low season to find off-peak deals. If it's a spontaneous trip, check out our last-minute deals on Melrose hotels.

Can I book Melrose hotels with free cancellation?

In order to book a refundable Melrose hotel, simply filter hotels by "Property cancellation options" and select "Fully refundable property". The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

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