Hotels in Mesilla

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This weekend
May 29 - May 31
Next weekend
Jun 5 - Jun 7

Where to stay in Mesilla?

Lobby

Drury Inn & Suites Las Cruces

Drury Inn & Suites Las Cruces
3.0 star property
Las Cruces
9.4 out of 10, Exceptional, (1,007 reviews)
Start your day with complimentary breakfast before exploring nearby vineyards. After sightseeing, unwind in the relaxing hot tub or take a dip in the indoor pool. Business travelers appreciate the free WiFi and parking, plus the attentive staff that guests consistently praise.
The price is CNY717
CNY830 total
includes taxes & fees
Jun 7 - Jun 8
Drury Inn & Suites Las Cruces
Indoor pool

Comfort Inn & Suites Las Cruces Mesilla

Comfort Inn & Suites Las Cruces Mesilla
2.5 star property
Las Cruces
8.8 out of 10, Excellent, (1,000 reviews)
Escape to the Mesilla area where an indoor pool and hot tub await after winery visits. Just 15 minutes from New Mexico State University, this hotel offers free breakfast, WiFi, and parking, plus in-room microwaves and refrigerators.
The price is CNY644
CNY748 total
includes taxes & fees
Jun 28 - Jun 29
Comfort Inn & Suites Las Cruces Mesilla
Deluxe Room, 2 Double Beds, Non Smoking, Mountain View | Premium bedding, desk, iron/ironing board, free cribs/infant beds

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
3.0 star property
Las Cruces
8.2 out of 10, Very Good, (2,392 reviews)
Surrounded by breathtaking scenery, this quiet hotel offers an outdoor pool and comfortable beds near restaurants and stores. Just 15 minutes from New Mexico State University with easy freeway access, enjoy free breakfast and helpful staff.
The price is CNY408
CNY480 total
includes taxes & fees
Jun 7 - Jun 8
La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
Restaurant

Hampton Inn & Suites Las Cruces I-10

Hampton Inn & Suites Las Cruces I-10
2.5 star property
Las Cruces
8.8 out of 10, Excellent, (1,003 reviews)
This business-friendly hotel offers free breakfast, WiFi, and parking in Las Cruces. Visit nearby Luna Rossa Winery & Pizzeria or Rio Grande Vineyards, then return to clean, comfortable rooms praised by travelers for their immaculate condition.
The price is CNY829
CNY957 total
includes taxes & fees
Jun 28 - Jun 29
Hampton Inn & Suites Las Cruces I-10
Free daily buffet breakfast

Best Western Mission Inn

Best Western Mission Inn
2.5 star property
Las Cruces
8.8 out of 10, Excellent, (1,223 reviews)
This serene Las Cruces hotel offers comfortable beds and a refreshing outdoor pool just minutes from campus. Enjoy the complimentary buffet breakfast before exploring nearby Luna Rossa Winery or local theaters, with free parking for added convenience.
The price is CNY579
CNY673 total
includes taxes & fees
Jun 3 - Jun 4
Best Western Mission Inn
Exterior

Days Inn by Wyndham Las Cruces

Days Inn by Wyndham Las Cruces
2.5 star property
Las Cruces
8.2 out of 10, Very Good, (1,505 reviews)
The price is CNY328
CNY389 total
includes taxes & fees
Jun 28 - Jun 29
Days Inn by Wyndham Las Cruces
Lobby

Ramada Hotel & Conference Center by Wyndham Las Cruces

Ramada Hotel & Conference Center by Wyndham Las Cruces
3.0 star property
Las Cruces
8.0 out of 10, Very Good, (1,006 reviews)
Soak up relaxing vibes at this peaceful hotel featuring a beautiful courtyard, indoor pool, and full-service spa. Located near American Southwest Theater Company with helpful staff ready to enhance your stay.
The price is CNY542
CNY630 total
includes taxes & fees
Jun 1 - Jun 2
Ramada Hotel & Conference Center by Wyndham Las Cruces
Free daily continental breakfast

Holiday Inn Express Hotel and Suites Las Cruces by IHG

Holiday Inn Express Hotel and Suites Las Cruces by IHG
2.5 star property
Las Cruces
7.8 out of 10, Good, (1,000 reviews)
Located near American Southwest Theater Company, this hotel offers round-the-clock fitness options and an indoor pool for year-round enjoyment. Guests love the helpful staff and clean rooms, plus free breakfast, WiFi, and parking enhance your New Mexico visit.
The price is CNY758
CNY874 total
includes taxes & fees
Jun 5 - Jun 6
Holiday Inn Express Hotel and Suites Las Cruces by IHG
Suite, 2 Double Beds | Down comforters, in-room safe, desk, laptop workspace

Springhill Suites By Marriott Las Cruces

Springhill Suites By Marriott Las Cruces
3.0 star property
Las Cruces
8.4 out of 10, Very Good, (1,002 reviews)
This modern hotel offers a peaceful atmosphere near Luna Rossa Winery and Rio Grande Vineyards. Start your day with free breakfast, then unwind in the outdoor pool and hot tub. Clean rooms with sofa beds welcome you back after exploring local shops.
The price is CNY724
CNY838 total
includes taxes & fees
Jun 7 - Jun 8
Springhill Suites By Marriott Las Cruces
View from property

Courtyard by Marriott Las Cruces at NMSU

Courtyard by Marriott Las Cruces at NMSU
3.0 star property
Las Cruces
9.2 out of 10, Wonderful, (556 reviews)
Moments from New Mexico State University, this modern hotel offers a refreshing outdoor pool and 24-hour fitness center. Grab breakfast or dinner at The Bistro, unwind at the bar, and appreciate free WiFi and parking during your Las Cruces adventure.
The price is CNY968
CNY1,115 total
includes taxes & fees
Jun 14 - Jun 15
Courtyard by Marriott Las Cruces at NMSU
Full-size fridge, microwave, toaster, cookware/dishes/utensils

Motel 9 Las Cruces

Motel 9 Las Cruces
2.5 star property
Las Cruces
6.4 out of 10, (323 reviews)
Just a 5-minute walk from New Mexico State University, this motel offers convenient free WiFi and parking. Near American Southwest Theater Company and Luna Rossa Winery, with 24-hour front desk service for hassle-free stays.
The price is CNY365
CNY431 total
includes taxes & fees
May 31 - Jun 1
Motel 9 Las Cruces
House (3 Bedrooms) | Interior

Las Cruces Home w/ Fenced Yard: Recently Remodeled

Las Cruces Home w/ Fenced Yard: Recently Remodeled
3.0 star property
Las Cruces
10.0 out of 10, Exceptional, (1 review)
This cozy Las Cruces cottage provides a tranquil retreat with a private patio and fully equipped kitchen. Located near the Community Theatre and just 14 minutes from the airport, you'll appreciate the free parking and comfortable air-conditioned accommodations.
The price is CNY704
CNY1,730 total
includes taxes & fees
May 31 - Jun 1
Las Cruces Home w/ Fenced Yard: Recently Remodeled
Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, sun loungers

Hotel Encanto de Las Cruces

Hotel Encanto de Las Cruces
3.5 star property
Las Cruces
9.2 out of 10, Wonderful, (1,797 reviews)
Experience tranquility at this Las Cruces retreat featuring an outdoor pool, 3 bars, and a nightclub. Comfortable beds await after exploring nearby Mesilla Valley Mall or watching stunning sunsets over the mountains from your historic-charm accommodations.
The price is CNY694
CNY987 total
includes taxes & fees
May 31 - Jun 1
Hotel Encanto de Las Cruces
Interior

Hilton Garden Inn Las Cruces

Hilton Garden Inn Las Cruces
3.0 star property
Las Cruces
9.2 out of 10, Wonderful, (1,001 reviews)
Wake up refreshed at this Las Cruces haven with a 24-hour fitness center and soothing hot tub. Grab dinner at Great American Grille or unwind at the bar after exploring nearby Pan American Center and Aggie Memorial Stadium. Rooms include microwaves and refrigerators for added convenience.
The price is CNY788
CNY910 total
includes taxes & fees
Jun 7 - Jun 8
Hilton Garden Inn Las Cruces
House, 2 Bedrooms | Living area | Smart TV, streaming services

Desert Haven Cozy 2-Bedroom Mobile Home Near NMSU 2 Home

Desert Haven Cozy 2-Bedroom Mobile Home Near NMSU 2 Home
3.0 star property
Las Cruces
This vacation home provides a smart TV and in-room coffeemaker for your comfort. Nearby hiking and biking trails offer outdoor adventure, while free WiFi keeps you connected. American Southwest Theater Company and Pan American Center are just minutes away.
The price is CNY885
CNY2,707 total
includes taxes & fees
May 31 - Jun 1
Desert Haven Cozy 2-Bedroom Mobile Home Near NMSU 2 Home
Restaurant

Hampton Inn & Suites Las Cruces I-25

Hampton Inn & Suites Las Cruces I-25
2.5 star property
Las Cruces
8.4 out of 10, Very Good, (1,000 reviews)
The price is CNY771
CNY891 total
includes taxes & fees
Jun 28 - Jun 29
Hampton Inn & Suites Las Cruces I-25
Lobby

Comfort Suites University Las Cruces

Comfort Suites University Las Cruces
2.5 star property
Las Cruces
8.0 out of 10, Very Good, (1,001 reviews)
Find a tranquil retreat at this golf-adjacent Las Cruces hotel featuring an indoor pool and fitness center. Located near Pan American Center and Aggie Memorial Stadium, enjoy complimentary breakfast, WiFi, and parking while experiencing the attentive service that guests consistently praise.
The price is CNY606
CNY704 total
includes taxes & fees
Jun 28 - Jun 29
Comfort Suites University Las Cruces
Indoor pool

Comfort Suites Las Cruces I-25 North

Comfort Suites Las Cruces I-25 North
2.5 star property
Las Cruces
9.2 out of 10, Wonderful, (1,001 reviews)
This business-friendly hotel offers a rejuvenating indoor pool, hot tub, and spa services. Enjoy free breakfast, WiFi, and parking while exploring nearby Sonoma Ranch Golf Course. In-room refrigerators and microwaves add convenience to your southwestern stay.
The price is CNY794
CNY942 total
includes taxes & fees
Jun 28 - Jun 29
Comfort Suites Las Cruces I-25 North
Pool

Quality Inn & Suites Las Cruces - University Area

Quality Inn & Suites Las Cruces - University Area
2.5 star property
Las Cruces
7.0 out of 10, Good, (1,000 reviews)
Wake to a complimentary continental breakfast at this peaceful Las Cruces retreat. Located near Luna Rossa Winery and Rio Grande Vineyards, this hotel offers free WiFi and parking. Guests consistently praise the helpful staff and clean, quiet rooms.
The price is CNY373
CNY440 total
includes taxes & fees
Jun 30 - Jul 1
Quality Inn & Suites Las Cruces - University Area
Exterior

La Quinta Inn by Wyndham Las Cruces Mesilla Valley

La Quinta Inn by Wyndham Las Cruces Mesilla Valley
3.0 star property
Las Cruces
5.2 out of 10, (1,004 reviews)
This welcoming Las Cruces hotel offers clean accommodations with complimentary WiFi and parking. Work out in the fitness center before exploring nearby attractions like Luna Rossa Winery & Pizzeria and Rio Grande Vineyards, just a 10-minute drive from the airport.
The price is CNY299
CNY357 total
includes taxes & fees
Jun 29 - Jun 30
La Quinta Inn by Wyndham Las Cruces Mesilla Valley
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top landmarks in Mesilla

Mesillia Plaza

4.6/5 (5 reviews)
Get a few outdoor pics when passing through Mesillia Plaza, located 0.4 mi (0.7 km) from central Mesilla.
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Learn more about Mesilla

Centuries-old adobe buildings frame the historic plaza, where the Confederate Territory of Arizona once claimed its brief capital. Duck into La Posta de Mesilla, a former stagecoach stop now serving chile rellenos that locals defend with patriotic fervor. The Fountain Theatre screens independent films in what might be the oldest movie house in the Southwest. Browse galleries where artists capture desert light in ways that make you understand why Georgia O'Keeffe never left. The Mesilla Plaza, a National Historic Landmark, hosts festivals where the smell of roasting green chiles mingles with mariachi music. Las Cruces sits just next door with its Museum of Nature & Science when you've had your fill of history.

See all hotels in Mesilla
Red chile doorway Mesilla NM

Check out reviews of Mesilla hotels guests love

Drury Inn & Suites Las Cruces

Drury Inn & Suites Las Cruces

8/10 Good
"Friendly staff and convenient location"
Michael 1-night trip
Posted 2 hours ago
Drury Inn & Suites Las Cruces

Frequently asked questions

How much does a hotel room cost in Mesilla?
You can discover great hotels in Mesilla from CNY357 with properties to suit all budgets and needs. If you're looking for an affordable hotel in Mesilla that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com.
How can I find deals and earn rewards at Mesilla hotels?
Discover great deals on Mesilla hotel stays with Hotels.com. Take a look at hotel prices mid-week or during the low season as to find those off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Mesilla hotels.
Can I book Mesilla hotels with free cancellation?
In order to book a refundable Mesilla hotel, simply filter hotels by "Property cancellation options" and select "Fully refundable property". The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
What are some popular hotels in central Mesilla?
If you're looking for hotels in central Mesilla, check out La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain and Drury Inn & Suites Las Cruces. Travelers love La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain for its location, as well as the outdoor pool, free continental breakfast and free parking this hotel offers. Drury Inn & Suites Las Cruces is another popular central hotel with an indoor pool, a hot tub and a free buffet breakfast. Picacho Hills is a central neighborhood for your Mesilla vacation.
What hotels do travelers like in Mesilla?
Guests like Hotel Encanto de Las Cruces, Days Inn by Wyndham Las Cruces and La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain.
Can I book a refundable hotel in Mesilla?
If you want the flexibility to change your travel plans to Mesilla, most accommodations offer refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where can I stay in Mesilla if I want a vacation rental instead of a traditional hotel?
If you're looking for a good alternative to a hotel, review our selection of 8 vacation homes.
What will the weather in Mesilla be like during my trip?
The warmest months in Mesilla are usually June and July with an average temp of 82°F. January and December are the chilliest months when the average temp is 48°F. The rainiest months are August and September.
Why should I book my Mesilla accommodation with Hotels.com?
There are plenty of reasons to book your Mesilla travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.