Photo by Ryan Coleman

Hotels in Sikeston

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Check prices for these dates

Tonight
Dec 25 - Dec 26
Tomorrow
Dec 26 - Dec 27
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

Where to stay in Sikeston?

Lobby
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
9.6 out of 10, Exceptional, (1001)
  • cleanliness
    Explore the stunning forest views with free breakfast, indoor pool, and dining options.
The price is CNY631
CNY712 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Drury Plaza Hotel Cape Girardeau Conference Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Budget hotels in Sikeston and vicinity

Reception
OYO Malden Airport Inn

OYO Malden Airport Inn

OYO Malden Airport Inn
2.5 star property
Malden
7.0 out of 10, Good, (68)
The price is CNY342
CNY412 total
includes taxes & fees
Jan 5 - Jan 6, 2026
OYO Malden Airport Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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When is the best time to visit Sikeston?

Our prices for hotels in Sikeston are cheapest in December
Price trends for hotels in Sikeston
Pricing is based on two traveler single night rates
View properties in December
Currently viewing crowd sizes and weather for December.
Typical weather for Sikeston
December
Low crowds
High 9°C / low 2°C. Partly sunny.
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9°
weather_partly_sunny
December, Low crowds, average high temperature 9 degrees Celsius, average low temperature 2 degrees Celsius. Partly sunny.
2°
6°
weather_partly_sunny
January, Low crowds, average high temperature 6 degrees Celsius, average low temperature -1 degrees Celsius. Partly sunny.
-1°
8°
weather_partly_sunny
February, Low crowds, average high temperature 8 degrees Celsius, average low temperature 0 degrees Celsius. Partly sunny.
0°
14°
weather_partly_sunny
March, Moderate crowds, average high temperature 14 degrees Celsius, average low temperature 5 degrees Celsius. Partly sunny.
5°
20°
weather_sun
April, High crowds, average high temperature 20 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
10°
25°
weather_sun
May, Moderate crowds, average high temperature 25 degrees Celsius, average low temperature 16 degrees Celsius. Sunny most days.
16°
30°
weather_sun
June, High crowds, average high temperature 30 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
20°
32°
weather_sun
July, High crowds, average high temperature 32 degrees Celsius, average low temperature 22 degrees Celsius. Sunny most days.
22°
31°
weather_sun
August, High crowds, average high temperature 31 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
21°
28°
weather_sun
September, Moderate crowds, average high temperature 28 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
17°
21°
weather_sun
October, Moderate crowds, average high temperature 21 degrees Celsius, average low temperature 11 degrees Celsius. Sunny most days.
11°
14°
weather_partly_sunny
November, Low crowds, average high temperature 14 degrees Celsius, average low temperature 5 degrees Celsius. Partly sunny.
5°
Monthly weather averages (˚C)

Top landmarks in Sikeston

City of Miner Convention Center

City of Miner Convention Center is worth a visit when in central Miner.
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Sikeston Depot Museum

3.8/5 (33 reviews)
The center of Sikeston is home to cultural attractions like Sikeston Depot Museum, so you might want to stop by during your stay. If you want to experience more of the culture Sikeston has to offer, head to City of Miner Convention Center and Central Park.
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Sikeston and related destinations

Admired for its riverfront and university life, Sikeston features attractions such as City of Miner Convention Center and Sikeston Depot Museum. This family-friendly city's sights include Central Park and visitors speak highly of the local restaurants.

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The best restaurant I have EVER been to! Hands down!!!
Photo by Ryan Coleman
Open Photo by Ryan Coleman

Check out reviews of Sikeston hotels guests love

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

10/10 Excellent
"Everything was excellent. Verify happy with everything. Stayed 3 weeks for work and already booked 2 more stays."
James 21-night trip
Posted 2 days ago
Days Inn and Suites by Wyndham Sikeston

Frequently asked questions

How much does a hotel room cost in Sikeston?
You can choose a great hotel in Sikeston from CNY444 with properties to suit all budgets and needs. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) is one low-cost option that's popular with our travelers. If you're looking for an affordable hotel in Sikeston that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com.
How can I find deals and earn rewards at Sikeston hotels?
Discover great deals on Sikeston hotel stays with Hotels.com. Take a look at hotel prices mid-week or during the low season as to find those off-peak deals. And make sure to check out our last-minute deals on Sikeston hotels.
Can I book Sikeston hotels with free cancellation?
It's easy to book a refundable Sikeston hotel on Hotels.com. Simply filter hotels by "Property cancellation options" and select "Fully refundable property". The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
What are some top pet-friendly hotels in Sikeston?
Consider one of our travelers' favorite pet-friendly hotels in Sikeston:You can also use the "Amenities" filter in your search on Hotels.com and check "Pet friendly" to discover more pet-friendly hotels in Sikeston.
What are some of the best hotels in Sikeston for couples?
Choose a top-rated Sikeston romantic hotel and enjoy your couple's getaway. Our travelers love TownePlace Suites by Marriott Sikeston, a hotel with an indoor pool. Discover more hotels in Sikeston on Hotels.com for couples by using the "Traveler experience" filter in your search and selecting "Adults only" or "Romantic".
What are some of the best kid-friendly hotels in Sikeston?
One of the best Sikeston hotels for kids is Drury Inn & Suites Sikeston, MO. Drury Inn & Suites Sikeston, MO is a kid-friendly hotel with a guest score of 9.4 out of 10 offering family-friendly amenities like an outdoor pool and free parking, plus free cribs in guestrooms. Explore more kid-friendly hotels in Sikeston by using our "Family friendly" filter in your search on Hotels.com.
What are the top Sikeston hotels with a pool?
For a little extra luxury, discover some of the best Sikeston hotels with a pool. Drury Inn & Suites Sikeston, MO is a great hotel with an outdoor pool and an indoor pool, and a guest rating of 9.4 out of 10. Plus, you can make the most of its free buffet breakfast and free parking. TownePlace Suites by Marriott Sikeston is a popular hotel that features an indoor pool along with a free self-serve breakfast and wedding services. To find more stays in Sikeston with a pool, use the "Amenities" filter on Hotels.com in your search and select "Pool".
What are some of the best Sikeston hotels with free parking?
If you're driving, a great Sikeston hotel with free parking is a bonus. Our travelers' favorites include:
What are some popular hotels in central Sikeston?
If you're looking for hotels in central Sikeston, check out Drury Inn & Suites Sikeston, MO and TownePlace Suites by Marriott Sikeston. Travelers love Drury Inn & Suites Sikeston, MO for its location, as well as the outdoor pool, free buffet breakfast and free parking this hotel offers. TownePlace Suites by Marriott Sikeston is another popular central hotel with an indoor pool, a free self-serve breakfast and free parking.
Can I book a refundable accommodation in Sikeston?
If you're looking for the flexibility to change your travel plans to Sikeston, most properties provide refundable* rates you can book. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Sikeston if I want a cheap accommodation?
Two inexpensive options worth considering are Hampton Inn Sikeston and Days Inn and Suites by Wyndham Sikeston.
What will the weather in Sikeston be like during my vacation?
The warmest months in Sikeston are usually July and August with an average temp of 77°F. January and February are the chilliest months when the average temp is 41°F. The rainiest months are April and March.