Hotels in Santee

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Where to stay in Santee?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

When is the best time to visit Santee?

Our prices for hotels in Santee are cheapest in February
Price trends for hotels in Santee
Pricing is based on two traveler single night rates
View properties in November
Currently viewing crowd sizes and weather for November.
Typical weather for Santee
November
High crowds
High 19°C / low 9°C. Sunny most days.
View properties in November
19°
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November, High crowds, average high temperature 19 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
15°
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December, High crowds, average high temperature 15 degrees Celsius, average low temperature 7 degrees Celsius. Sunny most days.
13°
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January, Low crowds, average high temperature 13 degrees Celsius, average low temperature 4 degrees Celsius. Sunny most days.
16°
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February, Low crowds, average high temperature 16 degrees Celsius, average low temperature 6 degrees Celsius. Sunny most days.
19°
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March, High crowds, average high temperature 19 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
24°
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April, Moderate crowds, average high temperature 24 degrees Celsius, average low temperature 13 degrees Celsius. Sunny most days.
13°
28°
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May, Moderate crowds, average high temperature 28 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
17°
31°
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June, Moderate crowds, average high temperature 31 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
21°
33°
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July, Moderate crowds, average high temperature 33 degrees Celsius, average low temperature 23 degrees Celsius. Sunny most days.
23°
32°
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August, Low crowds, average high temperature 32 degrees Celsius, average low temperature 23 degrees Celsius. Sunny most days.
23°
29°
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September, Low crowds, average high temperature 29 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
20°
24°
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October, High crowds, average high temperature 24 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
15°
Monthly weather averages (˚C)

Top landmarks in Santee

Learn more about Santee

Tee off at championship golf courses or cast a line in Lake Marion's fish-rich waters where locals claim the bass practically jump into your boat. The Santee National Wildlife Refuge offers hiking trails where alligators sun themselves with reptilian nonchalance. Interstate 95 crosses the lake on a causeway that provides views worth pulling over for (safely, of course). Santee State Park delivers lakeside tranquility that makes visitors forget their phones exist. This resort town punches well above its weight with dining options that range from fresh-caught catfish to surprisingly sophisticated fare. The recent addition of the Santee Cooper Regional Water System has locals buzzing about growth while still cherishing their small-town atmosphere.

Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina

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Frequently asked questions

What accommodations do travelers like in Santee?
Hampton Inn Santee-I-95, Fairfield Inn & Suites by Marriott Santee and Tru By Hilton Santee are all accommodations that are popular with guests.
Can I book refundable accommodations in Santee?
If you want the flexibility to change your plans to Santee, most accommodations provide refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where should I stay in Santee if I'm looking for a reasonably priced accommodation?
A few inexpensive options worth considering are Tru By Hilton Santee, Baymont by Wyndham Santee and Hampton Inn Santee-I-95.
Where can I stay in Santee if I want a vacation rental instead of a hotel?
Browse 9 vacation homes on our site. You also might want to book one of 92 condos for your trip.
What will the weather in Santee be like during my vacation?
July and August are typically the warmest months in Santee when the average temp is 79°F. January and February are the coldest months when the average temperature is 52°F. August and July are the months with the most rain.
Why should I book my Santee hotel with Hotels.com?
There are lots of reasons to book your Santee trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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