Hotels in Santee

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

This weekend
Next weekend

Where to stay in Santee?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Santee on Hotels.com. These Santee hotels consistently deliver on comfort, location and traveler experience. Last updated on .

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1,004 reviews)
Guests love this quiet Santee hotel for its helpful staff and complimentary breakfast. The outdoor pool and health club offer refreshing workout options, while free parking and WiFi add convenience. Golf enthusiasts will appreciate the nearby Santee Cooper Country Club.
The price is CNY908
CNY1,007 total
includes taxes & fees
Jul 1 - Jul 2
Fairfield Inn & Suites by Marriott Santee

Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1,003 reviews)
The price is CNY845
CNY938 total
includes taxes & fees
Jul 6 - Jul 7
Hampton Inn Santee-I-95

Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (863 reviews)
Bright, modern hotel near Santee National Golf Club with a refreshing indoor pool for year-round swimming. Guests love the complimentary breakfast, 24-hour fitness center, and helpful staff. Free WiFi and parking add convenience to your Santee visit.
The price is CNY717
CNY796 total
includes taxes & fees
Jul 8 - Jul 9
Tru By Hilton Santee

Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,005 reviews)
The price is CNY758
CNY841 total
includes taxes & fees
Jun 25 - Jun 26
Best Western Plus Santee Inn

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,004 reviews)
This peaceful hotel in Santee's entertainment district offers a quiet retreat with free breakfast and parking. Located near Santee Cooper Country Club, guests can enjoy the fitness center or take a refreshing dip in the seasonal pool. The staff earns consistent praise for their helpfulness.
The price is CNY711
CNY789 total
includes taxes & fees
Jul 20 - Jul 21
Comfort Inn & Suites Santee

Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,474 reviews)
Escape to this quiet Santee hotel where comfortable beds await after exploring local golf clubs. Free perks include daily continental breakfast, WiFi, and parking. Guests praise the convenient location close to everything they need.
The price is CNY508
CNY563 total
includes taxes & fees
Jun 25 - Jun 26
Baymont by Wyndham Santee

Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
3.0 star property
Santee
8.2 out of 10, Very Good, (1,000 reviews)
Swing into action at this golf-adjacent hotel featuring an indoor pool and 24-hour fitness center. Relax on the terrace or enjoy a drink at the bar after playing nearby Santee Cooper Country Club. Clean rooms with refrigerators and microwaves create a comfortable home base.
The price is CNY671
CNY745 total
includes taxes & fees
Jun 28 - Jun 29
Holiday Inn Santee by IHG

Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
2.0 star property
Santee
7.2 out of 10, Good, (742 reviews)
The price is CNY426
CNY473 total
includes taxes & fees
Jun 25 - Jun 26
Travelodge by Wyndham Santee

Super 8 by Wyndham Santee/I-95

Super 8 by Wyndham Santee/I-95
2.0 star property
Santee
6.8 out of 10, (468 reviews)
Overlooking a golf course, this tranquil motel offers a refreshing seasonal outdoor pool and complimentary breakfast served daily. Located near Santee Cooper Country Club, guests enjoy free WiFi and parking during their stay.
The price is CNY431
CNY479 total
includes taxes & fees
Jun 29 - Jun 30
Super 8 by Wyndham Santee/I-95

Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95
2.0 star property
Santee
6.4 out of 10, (566 reviews)
Steps from Santee Cooper Country Club, this hotel offers rooms with refrigerators and microwaves. After a round of golf, enjoy the poolside bar and on-site restaurant. Free WiFi and parking make exploring nearby attractions easy.
The price is CNY488
CNY542 total
includes taxes & fees
Jul 20 - Jul 21
Ramada by Wyndham Santee I-95

Red Roof Inn Santee

Red Roof Inn Santee
2.0 star property
Santee
6.6 out of 10, (656 reviews)
Minutes from Santee Cooper Country Club, this welcoming hotel offers free WiFi, parking, and daily continental breakfast. Adventure seekers will appreciate the nearby water skiing opportunities, while golf enthusiasts can enjoy Santee National Golf Club just a short drive away.
The price is CNY426
CNY473 total
includes taxes & fees
Jun 30 - Jul 1
Red Roof Inn Santee

Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
2.5 star property
Santee
6.0 out of 10, (547 reviews)
Wake up to free breakfast at this convenient Santee hotel with 7 dining options and a seasonal outdoor pool. After exploring nearby Santee Cooper Country Club, unwind at the bar. Clean rooms, helpful staff, and free WiFi and parking enhance your stay.
The price is CNY375
CNY454 total
includes taxes & fees
Jul 14 - Jul 15
Quality Inn & Suites Santee I-95

Econo Lodge Santee

Econo Lodge Santee
2.0 star property
Santee
6.4 out of 10, (314 reviews)
Located near Santee Cooper Country Club, this hotel offers free WiFi and parking. You'll appreciate the 24-hour front desk service while exploring nearby attractions including Santee National Golf Club.
The price is CNY409
CNY454 total
includes taxes & fees
Jul 19 - Jul 20
Econo Lodge Santee

Doyles B and B at Players course LLC

Doyles B and B at Players course LLC
3.5 star property
Manning
The price is CNY1,229
CNY1,364 total
includes taxes & fees
Jun 24 - Jun 25
Doyles B and B at Players course LLC

Peach Tree Inn

Peach Tree Inn
2.5 star property
St. George
7.2 out of 10, Good, (230 reviews)
The price is CNY417
CNY450 total
includes taxes & fees
Jun 24 - Jun 25
Peach Tree Inn

Hampton Inn & Suites Orangeburg

Hampton Inn & Suites Orangeburg
2.5 star property
Orangeburg
9.4 out of 10, Exceptional, (811 reviews)
Just minutes from Smith-Hammond-Middleton Memorial Center, this hotel offers a refreshing outdoor pool and morning workouts in the fitness center. Guests rave about the helpful staff and clean rooms, while free WiFi and parking enhance your stay.
The price is CNY882
CNY980 total
includes taxes & fees
Jul 12 - Jul 13
Hampton Inn & Suites Orangeburg

Fairfield Inn by Marriott Orangeburg

Fairfield Inn by Marriott Orangeburg
3.0 star property
Orangeburg
8.4 out of 10, Very Good, (787 reviews)
Near Smith-Hammond-Middleton Memorial Center, this business-friendly hotel offers free breakfast, WiFi, and parking. Take a refreshing dip in the seasonal outdoor pool or visit the fitness center. Clean rooms and helpful staff create a welcoming atmosphere.
The price is CNY786
CNY872 total
includes taxes & fees
Jun 24 - Jun 25
Fairfield Inn by Marriott Orangeburg

SpringHill Suites by Marriott Orangeburg

SpringHill Suites by Marriott Orangeburg
2.5 star property
Orangeburg
8.8 out of 10, Excellent, (771 reviews)
Dive into comfort at this Orangeburg hotel with an indoor pool and free perks like WiFi, parking, and breakfast. Helpful staff welcome you near Smith-Hammond-Middleton Memorial Center and I.P. Stanback Museum & Planetarium.
The price is CNY709
CNY787 total
includes taxes & fees
Jul 6 - Jul 7
SpringHill Suites by Marriott Orangeburg

Tru by Hilton Orangeburg

Tru by Hilton Orangeburg
2.5 star property
Orangeburg
9.2 out of 10, Wonderful, (1,004 reviews)
The price is CNY771
CNY856 total
includes taxes & fees
Jul 6 - Jul 7
Tru by Hilton Orangeburg

Holiday Inn Express & Suites Orangeburg by IHG

Holiday Inn Express & Suites Orangeburg by IHG
2.5 star property
Orangeburg
8.6 out of 10, Excellent, (837 reviews)
Relax in the seasonal outdoor pool after a workout in the 24-hour fitness center. This Orangeburg hotel offers clean rooms, free breakfast, WiFi, and parking near Smith-Hammond-Middleton Memorial Center and I.P. Stanback Museum & Planetarium.
The price is CNY860
CNY954 total
includes taxes & fees
Jul 5 - Jul 6
Holiday Inn Express & Suites Orangeburg by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Get last-minute hotel deals in Santee and save more

Sign in to unlock great savings.
Showing deals for:Jun 23 - Jun 24
Showing deals for:Jun 24 - Jun 25
Showing deals for:Jul 3 - Jul 5

Check out pet-friendly hotels in Santee

You may also like hotels with pools in Santee

You can also stay at family-friendly hotels in Santee

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

When is the best time to visit Santee?

Our prices for hotels in Santee are cheapest in December
Price trends for hotels in Santee
Pricing is based on two traveler single night rates
View properties in June
Currently viewing crowd sizes and weather for June.
Typical weather for Santee
June
High 31°C / low 21°C. Sunny most days.
View properties in June
31°
weather_sun
June, no crowd data, average high temperature 31 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
21°
33°
weather_sun
July, no crowd data, average high temperature 33 degrees Celsius, average low temperature 23 degrees Celsius. Sunny most days.
23°
32°
weather_sun
August, no crowd data, average high temperature 32 degrees Celsius, average low temperature 23 degrees Celsius. Sunny most days.
23°
29°
weather_sun
September, no crowd data, average high temperature 29 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
20°
24°
weather_sun
October, no crowd data, average high temperature 24 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
15°
19°
weather_sun
November, no crowd data, average high temperature 19 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
15°
weather_sun
December, no crowd data, average high temperature 15 degrees Celsius, average low temperature 7 degrees Celsius. Sunny most days.
13°
weather_sun
January, no crowd data, average high temperature 13 degrees Celsius, average low temperature 4 degrees Celsius. Sunny most days.
16°
weather_sun
February, no crowd data, average high temperature 16 degrees Celsius, average low temperature 6 degrees Celsius. Sunny most days.
19°
weather_sun
March, no crowd data, average high temperature 19 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
24°
weather_sun
April, no crowd data, average high temperature 24 degrees Celsius, average low temperature 13 degrees Celsius. Sunny most days.
13°
28°
weather_sun
May, no crowd data, average high temperature 28 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
17°
Monthly weather averages (˚C)

Top landmarks in Santee

Learn more about Santee

Tee off at championship golf courses or cast a line in Lake Marion's fish-rich waters where locals claim the bass practically jump into your boat. The Santee National Wildlife Refuge offers hiking trails where alligators sun themselves with reptilian nonchalance. Interstate 95 crosses the lake on a causeway that provides views worth pulling over for (safely, of course). Santee State Park delivers lakeside tranquility that makes visitors forget their phones exist. This resort town punches well above its weight with dining options that range from fresh-caught catfish to surprisingly sophisticated fare. The recent addition of the Santee Cooper Regional Water System has locals buzzing about growth while still cherishing their small-town atmosphere.

Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina

Check out reviews of Santee hotels guests love

Frequently asked questions

How much does a hotel room cost in Santee?
You can find top hotels in Santee from CNY450 with options to suit your budget and needs. Baymont by Wyndham Santee is one low-cost option that's popular with our travelers. If you're looking for an affordable hotel in Santee that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com.
How can I find deals and earn rewards at Santee hotels?
Discover great deals on Santee hotel stays with Hotels.com. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Santee hotels.
Can I book Santee hotels with free cancellation?
In order to book a refundable Santee hotel, simply filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
What are some top pet-friendly hotels in Santee?
Our travelers' top pet-friendly hotels in Santee include:You can also use the "Amenities" filter in your search on Hotels.com and check "Pet friendly" to discover more pet-friendly hotels in Santee.
What are the top Santee hotels with a pool?
For a little extra luxury, discover some of the best Santee hotels with a pool. Holiday Inn Santee by IHG is a great hotel with an indoor pool and a guest rating of 8.2 out of 10. Plus, you can make the most of its restaurant and bar/lounge. To find more stays in Santee with a pool, use the "Amenities" filter on Hotels.com in your search and select "Pool".
What are some of the best Santee hotels with free parking?
If you're exploring by car, finding a great Santee hotel with free parking is a win. Our travelers' favorites include:
What are some popular hotels in central Santee?
If you're looking for hotels in central Santee, check out Holiday Inn Santee by IHG. Travelers love Holiday Inn Santee by IHG for its location, as well as the indoor pool, restaurant and bar/lounge this hotel offers.
What accommodations do travelers like in Santee?
Can I book refundable accommodations in Santee?
If you want the flexibility to change your plans to Santee, most accommodations provide refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where should I stay in Santee if I'm looking for a reasonably priced accommodation?
A few inexpensive options worth considering are Baymont by Wyndham Santee, Tru By Hilton Santee and Best Western Plus Santee Inn.
Where can I stay in Santee if I want a vacation rental instead of a hotel?
Browse 7 vacation homes on our site. You also might want to book one of 89 condos for your trip.
What will the weather in Santee be like during my vacation?
July and August are typically the warmest months in Santee when the average temp is 79°F. January and February are the coldest months when the average temperature is 52°F. August and July are the months with the most rain.