Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in La Mesa on Hotels.com. These La Mesa hotels consistently deliver on comfort, location and traveler experience. Last updated on .
Hotels in La Mesa
Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices
Check prices for these dates
Tonight
Aug 14 - Aug 15Tomorrow
Aug 15 - Aug 16This weekend
Aug 14 - Aug 16Next weekend
Aug 21 - Aug 23Top 5 hotels in La Mesa at a glance
- 1. Best Western Plus La Mesa San Diego — 2.5-star hotel in La Mesa. Guest rating: 8.4/10 — Very Good.
- 2. Motel 6 La Mesa, CA - San Diego — 2-star hotel in La Mesa. Guest rating: 7.6/10 — Good.
- 3. Heritage Inn La Mesa — 2-star hotel in La Mesa. Guest rating: 7.0/10 — Good.
- 4. Mt. Nebo Oasis in La Mesa w/ Wraparound Deck — 3-star hotel in Windsor Hills.
- 5. Motel 6 La Mesa, CA — 2-star hotel in La Mesa. Guest rating: 7.4/10 — Good.
Where to stay in La Mesa?
1. Best Western Plus La Mesa San Diego
Best Western Plus La Mesa San DiegoLa Mesa
CNY912
CNY1,003 total
includes taxes & fees
Sep 13 - Sep 14
2. Motel 6 La Mesa, CA - San Diego
Motel 6 La Mesa, CA - San DiegoLa Mesa
CNY698
CNY769 total
includes taxes & fees
Aug 16 - Aug 17
3. Heritage Inn La Mesa
Heritage Inn La MesaLa Mesa
CNY513
CNY565 total
includes taxes & fees
Sep 13 - Sep 14
4. Mt. Nebo Oasis in La Mesa w/ Wraparound Deck
Mt. Nebo Oasis in La Mesa w/ Wraparound DeckWindsor Hills
CNY2,253
CNY4,974 total
includes taxes & fees
Aug 25 - Aug 26
5. Motel 6 La Mesa, CA
Motel 6 La Mesa, CALa Mesa
CNY734
CNY808 total
includes taxes & fees
Sep 15 - Sep 16
6. Lamplighter Inn & Suites at SDSU
Lamplighter Inn & Suites at SDSUMid-City
CNY870
CNY981 total
includes taxes & fees
Sep 13 - Sep 14
7. Hampton Inn San Diego-Kearny Mesa
Hampton Inn San Diego-Kearny MesaKearny Mesa
CNY803
CNY921 total
includes taxes & fees
Sep 13 - Sep 14
8. Motel 6 El Cajon, CA - San Diego
Motel 6 El Cajon, CA - San DiegoEl Cajon
CNY464
CNY512 total
includes taxes & fees
Aug 23 - Aug 24
9. Comfort Inn Chula Vista San Diego South
Comfort Inn Chula Vista San Diego SouthChula Vista
CNY734
CNY809 total
includes taxes & fees
Sep 7 - Sep 8
10. Best Western Plus Marina Gateway Hotel
Best Western Plus Marina Gateway HotelNational City
CNY1,026
CNY1,131 total
includes taxes & fees
Sep 7 - Sep 8
11. Ayres Hotel San Diego South - Chula Vista
Ayres Hotel San Diego South - Chula VistaOtay Ranch
CNY844
CNY930 total
includes taxes & fees
Sep 7 - Sep 8
12. La Quinta Inn by Wyndham San Diego Chula Vista
La Quinta Inn by Wyndham San Diego Chula VistaChula Vista
CNY780
CNY858 total
includes taxes & fees
Sep 8 - Sep 9
13. Holiday Inn Express San Diego South - Chula Vista by IHG
Holiday Inn Express San Diego South - Chula Vista by IHGChula Vista
CNY923
CNY1,015 total
includes taxes & fees
Sep 7 - Sep 8
14. DoubleTree by Hilton Hotel San Diego - Mission Valley
DoubleTree by Hilton Hotel San Diego - Mission ValleyMission Valley
CNY935
CNY1,074 total
includes taxes & fees
Aug 23 - Aug 24
15. Sycuan Casino Resort
Sycuan Casino ResortEl Cajon
CNY837
CNY1,002 total
includes taxes & fees
Sep 14 - Sep 15
16. Hampton Inn & Suites San Diego Airport Liberty Station
Hampton Inn & Suites San Diego Airport Liberty StationSan Diego
CNY1,125
CNY1,293 total
includes taxes & fees
Aug 23 - Aug 24
17. Hampton Inn San Diego/Mission Valley
Hampton Inn San Diego/Mission ValleyMission Valley
CNY879
CNY1,011 total
includes taxes & fees
Aug 23 - Aug 24
18. Town and Country San Diego
Town and Country San DiegoMission Valley
CNY1,198
CNY1,610 total
includes taxes & fees
Aug 29 - Aug 30
19. Best Western San Diego/Miramar Hotel
Best Western San Diego/Miramar HotelMiramar
CNY858
CNY987 total
includes taxes & fees
Sep 13 - Sep 14
20. Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Residence Inn by Marriott San Diego Downtown/Gaslamp QuarterDowntown San Diego
CNY1,128
CNY1,308 total
includes taxes & fees
Aug 28 - Aug 29
Go beyond your typical stay in La Mesa
Apart hotel
Family friendly
Resort
Pet friendly
Cottage
Our prices for hotels in La Mesa are cheapest in February
Our prices for hotels in La Mesa are cheapest in February
Price trends for hotels in La Mesa
Pricing is based on two traveler single night rates
Top neighborhoods in La Mesa
Casa de Oro-Mount Helix
La Mesa's Casa de Oro-Mount Helix neighborhood offers attractions including Mount Helix Park.
Mount Helix
The Mount Helix neighborhood offers attractions such as Mount Helix Park and FAITH CHAPEL.
Top landmarks in La Mesa
Mount Helix Park
7.4/10 (59 reviews)
If you're planning a bit of sightseeing head to Mount Helix Park— just one of the monuments in Casa de Oro-Mount Helix. Why not take a stroll along the port and watch the sunset while you're here? La Mesa has other landmarks you might want to visit such as Hotel del Coronado.
Computer Museum of America
6.6/10 (36 reviews)
Computer Museum of America is 1 mi (1.6 km) from central La Mesa, why not stop by during your stay. Hotels.com travelers also say the area is walkable and has lots of nice beaches. If you want to experience more of the culture La Mesa has to offer, head to San Diego State University, Sharp Grossmont Hospital, and Cal Coast Credit Union Open Air Theater.
La Mesa Memorial Fine Arts Center
La Mesa Memorial Fine Arts Center is in the heart of La Mesa, so why not stop by during your stay. If you have fun at La Mesa Memorial Fine Arts Center, you'll love Computer Museum of America, located nearby.
The Bancroft
If you find yourself in Mount Helix, you can stop off for a few drinks or snacks at The Bancroft.
Learn more about La Mesa
Between the bustle of San Diego and the quiet of the hills, La Mesa lives up to its 'Jewel of the Hills' nickname without trying too hard. The historic Village area offers boutiques and cafés where locals actually eat, not just places that survive on tourist traffic. Mount Helix rewards a short climb with panoramic views that explain why everyone in California seems suspiciously content. Lake Murray Park provides a refreshing escape where fishing lines dangle alongside kayakers who've discovered this urban oasis. Train enthusiasts find unexpected delight at the Pacific Southwest Railway Museum, where vintage locomotives sit frozen in time.
See all hotels in La Mesa
Check out reviews of La Mesa hotels guests love
Omni San Diego Hotel at the Ballpark
10/10 Excellent
"The staff, from the front desk to the valet staff to the restaurant staff, were attentive and enjoyable."
California Suites Hotel
10/10 Excellent
"everything works. the AC was a life saver."
Bay Club Hotel & Marina
10/10 Excellent
"good place"
Sheraton San Diego Resort
10/10 Excellent
"Hotels. Com was fantastic easy site the Sheraton hotel was very clean updated look and Staff checking in was very accommodating. The Housekeeping staff very helpful and took care of any requests The pool is well maintained clean area and towels. Great exercise facility updated equipment and very clean. The 2 restaurants one for breakfast was very good and the X Brewery also had good vibe and food. Very close to San Diego Airport. About 10 to 15 mins with car to Little Italy, Seaport Village and Petco Baseball Park. The only thing that was a little much was paying for Hotel parking that was $50 a day for self parking , valet was $67 a day or walk across the busy street for $ 15.00 a day. Make sure if you stay at this Hotel ask for a High floor for views floors 7 or higher ask for Marina view normally they are even room numbers 😁"
Manchester Grand Hyatt San Diego
10/10 Excellent
"Fantastic location. Market is criminally expensive. $8 for cup of coffee!"
Hard Rock Hotel San Diego
8/10 Good
"Had a great stay. The issue we had was in the sports bar area. We were watching a fight on the TV and it got changed. I asked why and they said a lady was upset."
Bahia Resort Hotel
10/10 Excellent
"The staff were very nice, loved all the things to do around the hotel. Would visit again."
The Sofia Hotel
10/10 Excellent
"Location was good for exploration"
Loews Coronado Bay Resort
8/10 Good
"The staff was amazing providing great customer service. The rooms can use some updates but I highly recommend for a short stay."
Frequently asked questions
Keep exploring
- Hotels with Free Breakfast in San Marcos
- Luxury Hotels near Dog Beach
- Hotels near Del Mar Fairgrounds
- Hotels with a Gym near Dog Beach
- Cottages in Poway
- Beach Hotels in La Jolla
- Hotels near 12th and Imperial Transit Center Station
- Hotels with Parking in Sorrento Valley
- Family Hotels in San Marcos
- Motels in San Diego
- Cheap Hotels in San Ysidro
- Hotels with a Gym in San Marcos
- Hotels with a Gym in Little Italy
- Hotels with a Pool near Carlsbad Lagoon
- Hotels near South Oceanside Beach
- Pet-Friendly Hotels in Julian
- Hotels near Boomers Vista
- Coronado Hotels
- Gaslamp Quarter Hotels
- Hotels near UC San Diego Health
- San Diego Hotels
- Luxury Hotels in Temecula
- Cheap Hotels in Fallbrook
- Hotels near 8th St Trolley Station
- Luxury Hotels near Carlsbad Lagoon
- Pet-Friendly Hotels near Tourmaline Surfing Park
- Hotels with Parking near Coronado Municipal Beach
- Resorts & Hotels with Spas in San Diego
- Bay Terraces Hotels
- Hotels near Del Mar Horsepark
- Family Hotels in San Clemente
- Lgbtqia Welcoming Hotels in Escondido
- Pet-Friendly Hotels in San Diego
- Vista Hotels
- Apartments in Coronado Municipal Beach
- Cheap Hotels in Little Italy
- Hotels near County Center - Little Italy Station
- Hotels with Kitchens near Carlsbad Lagoon
- Hotels near Grossmont Transit Center
- Hotels with Kitchens in Borrego Springs
- Hotels near Westfield UTC
- Cheap Hotels in San Diego
- Hotels near Massachusetts Avenue Station
- Hotels near Lenora Winery
- Hotels near Bernardo Winery
- Downtown San Diego Hotels
- Hotels near San Diego Zoo
- North Broadway Hotels
- Ocean Hills Hotels
- Hotels near Kaiser Permanente Otay Mesa Medical Offices
- Hotels with a Gym in San Clemente
- Terramar Hotels
- Cheap Hotels in El Cajon
- Cheap Hotels in Temecula
- Hotels near Mission Bay
- Lemon Grove Hotels
- Hotels near Barona Creek Golf Club
- Apartments in San Diego
- Hotels near 47th Street Station
- East Canyon Hotels
- San Marcos Hotels
- Hotels with Parking near Carlsbad Lagoon
- Family Hotels near Dog Beach