Hotels in South San Francisco
Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices
Check prices for these dates
Where to stay in South San Francisco?

Miller Apartments
Miller Apartments
Days Inn by Wyndham San Francisco S/Oyster Point Airport
Days Inn by Wyndham San Francisco S/Oyster Point Airport
Travelodge by Wyndham San Francisco Airport North
Travelodge by Wyndham San Francisco Airport North
DoubleTree by Hilton San Francisco South Airport Blvd
DoubleTree by Hilton San Francisco South Airport Blvd
Best Western Plus Grosvenor Airport Hotel
Best Western Plus Grosvenor Airport Hotel
Travelers Inn
Travelers Inn
Sonesta Select San Francisco Airport Oyster Point Waterfront
Sonesta Select San Francisco Airport Oyster Point Waterfront
Airport Inn
Airport Inn
AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront
AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront
Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area
Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area
Embassy Suites by Hilton San Francisco Airport Oyster Point
Embassy Suites by Hilton San Francisco Airport Oyster Point
Hilton Garden Inn San Francisco Arpt North
Hilton Garden Inn San Francisco Arpt North
Park Pointe Hotel
Park Pointe Hotel
Hotel Focus SFO
Hotel Focus SFO
Americana Inn
Americana Inn
La Quinta Inn & Suites by Wyndham San Francisco Airport N
La Quinta Inn & Suites by Wyndham San Francisco Airport N
Holiday Inn Express San Francisco-Airport North by IHG
Holiday Inn Express San Francisco-Airport North by IHG
Home2 Suites by Hilton San Francisco Airport North
Home2 Suites by Hilton San Francisco Airport NorthCheck out hotels with a pool in South San Francisco

AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront
AC Hotel by Marriott San Francisco Airport Oyster Point/WaterfrontYou can also stay at pet-friendly hotels in South San Francisco

Go beyond your typical stay in South San Francisco
Top neighborhoods in South San Francisco

Downtown South San Francisco
Downtown South San Francisco buzzes with a blend of biotech innovation and cultural diversity. Corporate towers and colorful murals tell the story of this unique business hub. You'll find authentic taquerias, dim sum houses, and Filipino eateries nestled between modern office campuses along Grand Avenue. The neighborhood comes alive during weekdays when professionals fill its plazas and restaurants. Getting around is a breeze with nearby BART and Caltrain stations connecting you to San Francisco proper and beyond. Business hotels cater mostly to corporate travelers with practical amenities. The area quiets down after work hours, offering a genuine glimpse into Bay Area life away from tourist crowds.

Oyster Point
Oyster Point balances sleek biotech campuses with stunning San Francisco Bay views. The waterfront promenade offers perfect spots for watching waves crash against the shore or catching a beautiful sunset. Modern plazas feature public art installations while walking paths showcase both cutting-edge architecture and natural bay ecosystems. Business travelers appreciate the corporate hotels with meeting facilities and convenient access to office buildings. Dining options cater primarily to weekday lunch crowds, with most establishments closing early evening. The area is best explored by car, though waterfront paths provide scenic strolling opportunities away from the corporate hustle.

The East Side
The East Side delivers authentic local life away from San Francisco's tourist traps. Catch Bay views from San Bruno Point Park or explore diverse family-owned restaurants along Grand Avenue serving up killer tacos and pho. This residential neighborhood mixes Hispanic and Asian influences that shine through local markets and casual eateries. Budget travelers appreciate the affordable motels and extended-stay options that cost way less than downtown San Francisco. Buses connect to BART and Caltrain, though having wheels helps. Most spots close early, so plan your food adventures accordingly.

Paradise Valley
Paradise Valley offers a peaceful retreat from San Francisco's bustle while keeping you close to the action. This quiet residential neighborhood in South San Francisco balances suburban calm with convenient access to nearby attractions. Take a stroll through San Bruno Point Park or venture to local spots like K1 Speed for some indoor racing fun. Budget-friendly accommodations make Paradise Valley an appealing base for Bay Area exploration. The neighborhood's proximity to San Francisco International Airport and major highways ensures easy connections throughout the region. With ample street parking and minimal crowds, you'll appreciate this low-key alternative to the city's more hectic districts.
Top landmarks in South San Francisco
Learn more about South San Francisco
Look beyond the iconic 'South San Francisco The Industrial City' sign crowning Sign Hill Park for a city with its own distinct identity. Grand Avenue serves up a global feast of family-run eateries where locals debate the merits of each dumpling house. San Bruno Mountain offers hiking trails with sweeping Bay views that explain why residents tolerate the fog. See's Candies factory tours satisfy sweet tooths, while K1 Speed delivers indoor racing thrills. The Convention Center hosts events that draw visitors who are surprised to discover this isn't simply San Francisco's southern neighborhood. Despite tripling in population since World War II, 'South City' maintains its working-class roots while embracing its role as a Peninsula destination in its own right.

Check out reviews of South San Francisco hotels guests love

Hyatt Regency San Francisco
Frequently asked questions
Keep exploring
- Hotels near Moscone Convention Center
- Pet-Friendly Hotels in San Ramon
- Hotels near UCSF Parnassus Station
- Hotels with Parking in Mountain View
- Pet-Friendly Hotels in Cupertino
- Hotels with Kitchens in San Mateo
- Hotels near 47th Ave & Cutler Ave Stop
- Family Hotels in Pacifica
- Luxury Hotels in North Beach
- Cheap Hotels in San Francisco
- Hotels near Church St & 27th St Stop
- Hotels near 17th St & Castro St Stop
- Hotels with Parking in Mill Valley
- Historic Hotels near Maiden Lane
- Hotels near San Francisco Intl.
- Hotels with Parking near Van Ness Avenue
- Business Hotels in Alameda
- Hotels with a Pool in Milpitas
- Hotels with a Gym in Dublin
- Luxury Hotels near Castro Street
- University Mound Hotels
- Shopping Hotels in North Beach
- Cottages in Oakland
- Hotels near Judah St & 31st Ave Stop
- Family Hotels in Sunnyvale
- Hotels near University of San Francisco
- Shopping Hotels in Burlingame
- Hotels near John McLaren Park
- Cheap Hotels in Mountain View
- Hotels near The Museum Store
- Historic Hotels near Castro Street
- Hotels with a Gym in Emeryville
- Apartments in Berkeley
- Baywood - Aragon Hotels
- Hotels near Church St & Clipper St Stop
- Hotels near Laguna Honda Hospital
- Hotels with a Gym in Millbrae
- Broadmoor Hotels
- Hotels with Parking near Old Oakland
- Daly City Hotels
- Hotels with Parking in San Mateo
- Avalon Hotels
- Hotels near Taraval St & 46th Ave Stop
- Family Hotels in Mountain View
- Motels in Cow Hollow
- Business Hotels in Cupertino
- Lgbtqia Welcoming Hotels in Menlo Park
- San Francisco Hotels
- Hotels with a Pool in Bay Area
- Hotels with a Pool in Novato
- Family Hotels in Milpitas
- Hotels near See's Candies
- Hotels with a Gym in Nob Hill
- Hotels with Parking in Sunnyvale
- B&B in Castro Street
- Hotels with Parking in Alameda
- Pet-Friendly Hotels in Newark
- Luxury Hotels in San Francisco
- Hotels with a Gym near Van Ness Avenue
- Cheap Hotels near Old Oakland
- Hotels with Kitchens in Milpitas
- Hotels near Ocean Ave & Cerritos Ave Stop
- Hotels with a Gym in Fremont
- Business Hotels near Old Oakland
- Bayshore Heights Hotels
- Hotels with Free Breakfast in Hayward
- Luxury Hotels near Gourmet Ghetto
- Apartments in Palo Alto
- Crocker-Amazon Hotels
- Hotels with a Pool in Newark
- Hotels with Free Breakfast in Alameda
- Pet-Friendly Hotels in San Francisco
- Apartments in Foster City
- Hotels near Randolph St & Bright St Stop
- Motels in Lake Elizabeth
- Lgbtqia Welcoming Hotels near Naples Beach
- Hotels with a Pool near Castro Street
- Hotels with Kitchens in Santa Clara
- Hotels with Parking in Castro Valley
- Hotels near Ocean Ave & Fairfield Way Stop
- Hotels near Ocean Ave & San Leandro Way Stop
- Merced Manor Hotels
- Business Hotels in Milpitas
- Luxury Hotels in Berkeley
- Cheap Hotels in Castro Valley
- Luxury Hotels in San Mateo
- Business Hotels in South Beach
- Pet-Friendly Hotels in San Mateo
- Ingleside Heights Hotels
- Hotels with Parking in Belmont
- Eureka Valley Hotels
- Hotels with Kitchens in Palo Alto
- Motels in Castro Street
- Hotels with Parking in Cupertino
- Hotels near Wawona Street & 46th Avenue Station
- Pet-Friendly Hotels in Mountain View
- Family Hotels in Newark














































































