Hotels in Isla Santa María

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Where to stay in Isla Santa María?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Isla Santa María

Post Office Bay
Swimming with sea turtles was one of the many amazing moments of my Galapagos adventure. Like most of the other animals, they went about their business without seeming to even notice the people around.

Post Office Bay

Commune with nature and explore the great outdoors at Post Office Bay during your travels in Isla Santa María. While you're in the area, wander around the natural setting.

Punta Suarez
I've been spotted! A family of marine iguanas auditioning for meerkat manor #LifeAtExpedia

Punta Suarez

Explore the great outdoors at Punta Suarez, a lovely green space in Isla Santa María. Wander the seaside and white-sand beaches while you're in the area.

Learn more about Isla Santa María

Isla Santa María is well-known for its attractions such as Galápagos National Park and Post Office Bay.

Check out reviews of Isla Santa María hotels guests love

Frequently asked questions

Can I book refundable hotels in Isla Santa María?
If you're looking for the flexibility to change your plans to Isla Santa María, most properties provide refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Isla Santa María be like during my trip?
With an average temperature of 72°F, Isla Santa María is a great place if you want to enjoy the sunshine year all year long.
Why should I book my Isla Santa María hotel through Hotels.com?
There are plenty of reasons to book your Isla Santa María travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.