A river with a bridge, steps leading to the water, and boats.

Business Hotels in Eastern Iowa

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Business Hotels in Eastern Iowa

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Eastern Iowa on Hotels.com. These Eastern Iowa Business Hotels consistently deliver on quality, location and traveler experience. Last updated on September 12, 2026.

Suite, 1 King Bed with Sofa bed, Jetted Tub

1. Cornerstone Inn & Suites

Oelwein

CNY631

CNY707 total

includes taxes & fees

Sep 25 - Sep 26

2. Boarders Inn & Suites by Cobblestone Hotels - Fayette

Fayette

CNY731

CNY819 total

includes taxes & fees

Sep 21 - Sep 22

Suite, 1 King Bed, Accessible, Non Smoking

3. Comfort Inn & Suites Independence

Independence

CNY881

CNY986 total

includes taxes & fees

Oct 11 - Oct 12

4. Isle Casino Hotel Waterloo - A Caesars Rewards Destination

Waterloo

CNY537

CNY692 total

includes taxes & fees

Oct 8 - Oct 9

5. American Inn and Suites

Peosta

CNY352

CNY370 total

includes taxes & fees

Oct 7 - Oct 8

6. Country Inn & Suites by Radisson, Waterloo, IA

Waterloo

CNY536

CNY600 total

includes taxes & fees

Sep 20 - Sep 21

7. Quality Inn & Suites Decorah

Decorah

CNY637

CNY714 total

includes taxes & fees

Sep 20 - Sep 21

8. AmericInn by Wyndham DeWitt

De Witt

CNY650

CNY728 total

includes taxes & fees

Sep 29 - Sep 30

9. Hotel Millwright

Amana

CNY755

CNY846 total

includes taxes & fees

Sep 23 - Sep 24

Standard Room, 2 Queen Beds, Non Smoking

10. Comfort Inn & Suites Davenport - Quad Cities

Davenport

CNY553

CNY620 total

includes taxes & fees

Sep 20 - Sep 21

11. Rhythm City Casino Resort

Davenport

CNY875

CNY980 total

includes taxes & fees

Oct 1 - Oct 2

Suite, Multiple Beds, Non Smoking, Jetted Tub

12. Cobblestone Inn & Suites – Manchester

Manchester

CNY912

CNY1,031 total

includes taxes & fees

Oct 7 - Oct 8

13. Comfort Inn & Suites Marquette - Prairie du Chien

Marquette

CNY496

CNY555 total

includes taxes & fees

Sep 23 - Sep 24

14. Fairfield Inn & Suites by Marriott Decorah

Decorah

CNY798

CNY894 total

includes taxes & fees

Sep 27 - Sep 28

15. Hilton Garden Inn Dubuque Downtown

Dubuque

CNY707

CNY792 total

includes taxes & fees

Sep 27 - Sep 28

16. Country Inn & Suites by Radisson, Cedar Falls, IA

Cedar Falls

CNY572

CNY667 total

includes taxes & fees

Sep 20 - Sep 21

17. Courtyard by Marriott Bettendorf

Bettendorf

CNY736

CNY824 total

includes taxes & fees

Sep 13 - Sep 14

18. AmericInn by Wyndham Anamosa

Anamosa

CNY736

CNY824 total

includes taxes & fees

Sep 23 - Sep 24

19. Holiday Inn & Suites Cedar Falls - Waterloo Event Ctr by IHG

Cedar Falls

CNY765

CNY856 total

includes taxes & fees

Sep 27 - Sep 28

20. Quality Inn & Suites Prairie Du Chien

Southside

CNY481

CNY532 total

includes taxes & fees

Oct 11 - Oct 12

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Top landmarks in Eastern Iowa

A large white house with a grey roof, surrounded by a white picket fence and green bushes.

Field of Dreams

9.4/10 (162 reviews)

Field of Dreams is 3.2 mi (5.1 km) from central Dyersville, why not stop by during your stay. If you want to experience more of the culture Dyersville has to offer, head to Dyersville City Hall, National Farm Toy Museum, and Basilica of St. Francis Xavier.

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A water park with slides, a water fountain, and a sign that reads "Lost City."

Lost Island Waterpark

8.0/10 (115 reviews)

Why not give yourself a treat with a trip to Lost Island Waterpark, one of the family attractions located 3.6 mi (5.8 km) from central Waterloo. If you have fun at Lost Island Waterpark, you'll love Lost Island Theme Park and Akua Maze, both a short walk away.

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A person standing on a moss-covered rock in a forested area with sunlight streaming through the trees.

Maquoketa Caves State Park

9.6/10 (80 reviews)

Maquoketa Caves State Park is 6.7 mi (10.8 km) from central Maquoketa, why not stop by during your stay.

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A building with a sign reading "Adlerman Winery Established 1956" and an American flag.

Amana Colonies

9.0/10 (269 reviews)

Amana Colonies is 0.4 mi (0.6 km) from central Amana, why not stop by during your stay. If you want to experience more of the culture Amana has to offer, head to Amana Heritage Museum, Amana Woolen Mill, and Amana Colonies Golf Course.

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Kinnick Stadium

9.2/10 (509 reviews)

You can catch an event at Kinnick Stadium, located 1.1 mi (1.8 km) from central Iowa City. If you think Kinnick Stadium is cool, you also might like Carver-Hawkeye Arena and Xtream Arena & GreenState Family Fieldhouse, both located nearby.

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Diamond Jo Casino

8.2/10 (479 reviews)

Diamond Jo Casino is 0.4 mi (0.6 km) from central Dubuque, why not stop by during your stay. Why not take a stroll along the riverfront and watch the sunset while you're here?

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The TBK Bank Sports Complex

8.6/10 (159 reviews)

The TBK Bank Sports Complex is 5.2 mi (8.3 km) from central Bettendorf, why not stop by during your stay. Why not take a stroll along the riverfront and watch the sunset while you're here?

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Riverside Casino and Golf Resort

8.4/10 (174 reviews)

Riverside Casino and Golf Resort is 2.8 mi (4.6 km) from central Riverside, why not stop by during your stay.

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