Hotels in Southwest Houston

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Where to stay in Southwest Houston?

Scottish Inns & Suites at NRG Park

Scottish Inns & Suites at NRG Park
2.5 star property
Astrodome
8.6 out of 10, Excellent, (450 reviews)
This Houston motel sits just a 5-minute drive from NRG Stadium, MD Anderson Cancer Center, and Houston Zoo. Enjoy free WiFi and parking while the 24-hour front desk ensures around-the-clock assistance. Stadium Park/Astrodome Station is an 18-minute walk away.
The price is CNY610
CNY713 total
includes taxes & fees
Jun 11 - Jun 12
Scottish Inns & Suites at NRG Park

Palace Inn Post Oak

Palace Inn Post Oak
2.5 star property
Houston
9.0 out of 10, Wonderful, (26 reviews)
The price is CNY516
CNY604 total
includes taxes & fees
Jun 11 - Jun 12
Palace Inn Post Oak

Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center
3.0 star property
Texas Medical Center
9.2 out of 10, Wonderful, (2,536 reviews)
Steps from Smith Lands Station, this Houston hotel offers easy access to MD Anderson Cancer Center and NRG Stadium. Cool off in the outdoor pool, relax in the hot tub, or maintain your routine at the 24-hour fitness center after enjoying the complimentary breakfast.
The price is CNY856
CNY1,007 total
includes taxes & fees
Jul 5 - Jul 6
Hyatt Place Houston Medical Center

Home2 Suites by Hilton Houston Medical Center, TX

Home2 Suites by Hilton Houston Medical Center, TX
3.0 star property
Texas Medical Center
9.4 out of 10, Exceptional, (673 reviews)
Experience comfort near MD Anderson Cancer Center with an inviting outdoor pool and 24-hour fitness center. The free breakfast energizes your day before exploring nearby Houston Zoo or catching events at NRG Stadium, all while friendly staff ensure a pleasant stay.
The price is CNY916
CNY1,071 total
includes taxes & fees
Jul 5 - Jul 6
Home2 Suites by Hilton Houston Medical Center, TX

Comfort Suites Houston near Medical Center- NRG Stadium

Comfort Suites Houston near Medical Center- NRG Stadium
2.5 star property
South Main
8.6 out of 10, Excellent, (1,007 reviews)
The price is CNY664
CNY777 total
includes taxes & fees
Jun 11 - Jun 12
Comfort Suites Houston near Medical Center- NRG Stadium

Relux at Westchase

Relux at Westchase
2.5 star property
Chinatown
9.2 out of 10, Wonderful, (27 reviews)
The price is CNY550
CNY643 total
includes taxes & fees
Jul 1 - Jul 2
Relux at Westchase

Palace Inn Blue US 59 & Gessner

Palace Inn Blue US 59 & Gessner
2.5 star property
Sharpstown
9.2 out of 10, Wonderful, (131 reviews)
Enjoy a business-friendly stay with free continental breakfast, WiFi, and parking. Just minutes from Arena Theater and a short drive to Rice University, NRG Stadium, and Houston Zoo. Clean rooms and helpful staff create a comfortable experience.
The price is CNY518
CNY606 total
includes taxes & fees
Jun 24 - Jun 25
Palace Inn Blue US 59 & Gessner

Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District
4.0 star property
Texas Medical Center
9.0 out of 10, Wonderful, (1,002 reviews)
Escape the busy Houston medical district at this peaceful retreat with American dining at Curate restaurant and convenient bar/lounge. Just minutes from MD Anderson and Rice University with complimentary area shuttle service to explore nearby NRG Stadium and Toyota Center.
The price is CNY1,091
CNY1,495 total
includes taxes & fees
Jul 10 - Jul 11
Houston Marriott Medical Center/Museum District

Wingate Houston near NRG Park/Medical Center

Wingate Houston near NRG Park/Medical Center
3.0 star property
South Main
6.6 out of 10, (1,006 reviews)
Cool off in the outdoor pool after exploring nearby attractions including NRG Park and MD Anderson Cancer Center. Just a 5-minute drive from major venues, this Houston hotel offers free breakfast and WiFi for a comfortable, convenient stay.
The price is CNY610
CNY713 total
includes taxes & fees
Jun 11 - Jun 12
Wingate Houston near NRG Park/Medical Center

Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton
4.0 star property
Texas Medical Center
9.0 out of 10, Wonderful, (3,885 reviews)
Discover soothing comfort just a 15-minute walk from MD Anderson Cancer Center. This Houston haven features 2 bars, an outdoor pool, and rejuvenating spa treatments. TMC Transit Center is 13 minutes away, with NRG Stadium and Toyota Center nearby.
The price is CNY1,072
CNY1,254 total
includes taxes & fees
Jul 9 - Jul 10
Blossom Hotel Houston, Curio Collection by Hilton

The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District
4.0 star property
Texas Medical Center
9.2 out of 10, Wonderful, (1,162 reviews)
Immerse yourself in Art Deco charm at this Houston hotel with an outdoor pool and poolside bar. Just steps from Dryden/TMC Station, you're a quick drive to MD Anderson Cancer Center, Houston Zoo, NRG Stadium, and Toyota Center.
The price is CNY1,274
CNY1,586 total
includes taxes & fees
Jul 5 - Jul 6
The Westin Houston Medical Center/Museum District

Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG

Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG
2.5 star property
Braeswood Place
9.4 out of 10, Exceptional, (1,001 reviews)
Wake up to free breakfast at this conveniently located Houston hotel near NRG Stadium and MD Anderson Cancer Center. Take a morning dip in the outdoor pool, work out anytime in the 24-hour fitness center, and enjoy complimentary WiFi and parking throughout your stay.
The price is CNY847
CNY996 total
includes taxes & fees
Jul 8 - Jul 9
Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG

Hyatt Place Houston/Galleria

Hyatt Place Houston/Galleria
3.0 star property
Greater Uptown
8.8 out of 10, Excellent, (1,484 reviews)
Just a 10-minute drive from Rice University, this Houston hotel offers an outdoor pool and fitness center. Enjoy free breakfast at the coffee shop, unwind at the bar, or order room service after exploring nearby NRG Stadium and Westheimer Road.
The price is CNY807
CNY949 total
includes taxes & fees
Jul 10 - Jul 11
Hyatt Place Houston/Galleria

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
4.5 star property
Texas Medical Center
8.4 out of 10, Very Good, (1,962 reviews)
Just a 5-minute drive from MD Anderson Cancer Center, this hotel offers an outdoor pool with poolside bar, 2 restaurants, and a 24-hour fitness center. Only 4 minutes from Dryden/TMC Station, guests love the quiet atmosphere, walkable location, and helpful staff.
The price is CNY673
CNY795 total
includes taxes & fees
Jul 5 - Jul 6
Hilton Houston Plaza/Medical Center

Hilton Garden Inn Houston Medical Center, TX

Hilton Garden Inn Houston Medical Center, TX
3.0 star property
Texas Medical Center
9.2 out of 10, Wonderful, (1,017 reviews)
Walking distance from MD Anderson Cancer Center, this hotel offers a convenient area shuttle, onsite restaurant, and bar. Close to Rice University and Houston Zoo, it's an ideal base for exploring NRG Park and Toyota Center while enjoying clean, comfortable accommodations.
The price is CNY887
CNY1,037 total
includes taxes & fees
Jun 21 - Jun 22
Hilton Garden Inn Houston Medical Center, TX

Hampton Inn & Suites Houston Medical Center NRG Park

Hampton Inn & Suites Houston Medical Center NRG Park
2.5 star property
Texas Medical Center
8.4 out of 10, Very Good, (1,018 reviews)
Near Houston's Medical Center and NRG Stadium, this peaceful hotel offers an outdoor pool and 24-hour fitness center. Just 5 minutes from Smith Lands Station, with free breakfast and WiFi. Clean rooms and helpful staff make this a perfect base for medical visits or events.
The price is CNY674
CNY792 total
includes taxes & fees
Jul 5 - Jul 6
Hampton Inn & Suites Houston Medical Center NRG Park

SpringHill Suites Houston Medical Center/NRG Park

SpringHill Suites Houston Medical Center/NRG Park
3.0 star property
Astrodome
9.0 out of 10, Wonderful, (1,000 reviews)
Unwind at this peaceful retreat just 5 minutes from NRG Stadium and MD Anderson Cancer Center. The outdoor pool, hot tub, and fitness center provide relaxation after exploring Houston. Smith Lands Station is only 8 minutes away on foot for easy city access.
The price is CNY948
CNY1,109 total
includes taxes & fees
Jul 9 - Jul 10
SpringHill Suites Houston Medical Center/NRG Park

The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria
4.0 star property
The Galleria
8.6 out of 10, Excellent, (2,000 reviews)
Cool off at the outdoor pool after exploring Houston's best shopping at this Galleria-area hotel. Just a short drive from Rice University and MD Anderson, you'll find a 24-hour fitness center, international cuisine at ARA, and a welcoming bar.
The price is CNY1,043
CNY1,221 total
includes taxes & fees
Jul 10 - Jul 11
The Royal Sonesta Houston Galleria

Crystal Suites

Crystal Suites
2.0 star property
Central Southwest
6.4 out of 10, (120 reviews)
Just a short drive from NRG Stadium and MD Anderson Cancer Center, this practical Houston motel offers complimentary WiFi and parking. NRG Park attractions are nearby, with easy access to Fannin South Station for exploring the city.
The price is CNY542
CNY634 total
includes taxes & fees
Jun 11 - Jun 12
Crystal Suites

Blue Diamond Inn

Blue Diamond Inn
2.0 star property
Central Southwest
6.6 out of 10, (9 reviews)
This Houston motel offers easy access to top attractions with NRG Park and Rice University nearby. Enjoy practical perks like free WiFi, complimentary self parking, and 24-hour front desk service, all just minutes from Hobby Airport.
The price is CNY579
CNY678 total
includes taxes & fees
Jun 11 - Jun 12
Blue Diamond Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Get last-minute hotel deals in Southwest Houston and save more

Sign in to unlock great savings.
Showing deals for:Jun 10 - Jun 11
Showing deals for:Jun 11 - Jun 12
Showing deals for:Jun 19 - Jun 21

You may also like family-friendly hotels in Southwest Houston

You can also stay at hotels with a pool in Southwest Houston

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Southwest Houston

Learn more about Southwest Houston

Southwest Houston is hailed for its sports and festivals while top attractions include NRG Stadium. The city has something for everyone including its live music, restaurants, and sights like Arena Theater and Harwin Drive Shopping District.

Photo by George Zimzores
Open Photo by George Zimzores

Check out reviews of Southwest Houston hotels guests love

Frequently asked questions

Why should I book my Southwest Houston hotel with Hotels.com?
There are lots of reasons to book your Southwest Houston trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Keep exploring