Hotels in South Main

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Check prices for these dates

Tonight
Feb 10 - Feb 11
Tomorrow
Feb 11 - Feb 12
This weekend
Feb 13 - Feb 15
Next weekend
Feb 20 - Feb 22

Where to stay in South Main?

Lobby

Wingate Houston near NRG Park/Medical Center

Wingate Houston near NRG Park/Medical Center
3.0 star property
South Main
6.6 out of 10, (1,004 reviews)
The price is CNY588
CNY688 total
includes taxes & fees
Feb 11 - Feb 12
Wingate Houston near NRG Park/Medical Center
Premium bedding, pillowtop beds, in-room safe, individually decorated

Wyndham Houston near NRG Park/Medical Center

Wyndham Houston near NRG Park/Medical Center
3.5 star property
South Main
7.2 out of 10, Good, (1,210 reviews)
The price is CNY692
CNY810 total
includes taxes & fees
Feb 16 - Feb 17
Wyndham Houston near NRG Park/Medical Center
Hypo-allergenic bedding, in-room safe, individually decorated

Quality Inn & Suites NRG Park - Medical Center

Quality Inn & Suites NRG Park - Medical Center
2.5 star property
South Main
6.6 out of 10, (1,002 reviews)
The price is CNY524
CNY613 total
includes taxes & fees
Feb 15 - Feb 16
Quality Inn & Suites NRG Park - Medical Center
Individually decorated, individually furnished, desk, laptop workspace

Comfort Suites Houston near Medical Center- NRG Stadium

Comfort Suites Houston near Medical Center- NRG Stadium
2.5 star property
South Main
8.6 out of 10, Excellent, (1,006 reviews)
The price is CNY740
CNY866 total
includes taxes & fees
Feb 21 - Feb 22
Comfort Suites Houston near Medical Center- NRG Stadium
Exterior

Candlewood Suites Houston Medical Center by IHG

Candlewood Suites Houston Medical Center by IHG
2.5 star property
South Main
7.4 out of 10, Good, (834 reviews)
The price is CNY513
CNY600 total
includes taxes & fees
Feb 16 - Feb 17
Candlewood Suites Houston Medical Center by IHG
Free daily continental breakfast

Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG

Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG
2.5 star property
1.4 km from South Main
9.4 out of 10, Exceptional, (1,004 reviews)
The price is CNY804
CNY947 total
includes taxes & fees
Feb 19 - Feb 20
Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG
Lobby

Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center
3.0 star property
Texas Medical Center, 3.1 km from South Main
9.2 out of 10, Wonderful, (2,326 reviews)
The price is CNY878
CNY1,033 total
includes taxes & fees
Feb 22 - Feb 23
Hyatt Place Houston Medical Center
Lobby

Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton
4.0 star property
Texas Medical Center, 3.5 km from South Main
9.0 out of 10, Wonderful, (3,736 reviews)
The price is CNY1,334
CNY1,561 total
includes taxes & fees
Feb 20 - Feb 21
Blossom Hotel Houston, Curio Collection by Hilton
Lobby

Hyatt House Houston Medical Center

Hyatt House Houston Medical Center
3.0 star property
Texas Medical Center, 3.1 km from South Main
9.2 out of 10, Wonderful, (1,237 reviews)
The price is CNY904
CNY1,063 total
includes taxes & fees
Feb 21 - Feb 22
Hyatt House Houston Medical Center
Terrace/patio

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
4.5 star property
Texas Medical Center, 4.4 km from South Main
8.4 out of 10, Very Good, (1,836 reviews)
The price is CNY588
CNY696 total
includes taxes & fees
Feb 22 - Feb 23
Hilton Houston Plaza/Medical Center
Bar (on property)

SpringHill Suites Houston Medical Center/NRG Park

SpringHill Suites Houston Medical Center/NRG Park
3.0 star property
Astrodome, 2.4 km from South Main
9.0 out of 10, Wonderful, (1,001 reviews)
The price is CNY728
CNY852 total
includes taxes & fees
Feb 22 - Feb 23
SpringHill Suites Houston Medical Center/NRG Park
Outdoor pool, free cabanas, pool umbrellas

The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District
4.0 star property
Texas Medical Center, 4.4 km from South Main
9.2 out of 10, Wonderful, (1,096 reviews)
The price is CNY1,001
CNY1,246 total
includes taxes & fees
Feb 15 - Feb 16
The Westin Houston Medical Center/Museum District
Terrace/patio

Hilton Garden Inn Houston Medical Center, TX

Hilton Garden Inn Houston Medical Center, TX
3.0 star property
Texas Medical Center, 4.7 km from South Main
9.4 out of 10, Exceptional, (1,007 reviews)
The price is CNY742
CNY868 total
includes taxes & fees
Feb 22 - Feb 23
Hilton Garden Inn Houston Medical Center, TX
Outdoor pool, open 9:00 AM to 10:00 PM, sun loungers

Crowne Plaza Houston Med Ctr-Galleria Area by IHG

Crowne Plaza Houston Med Ctr-Galleria Area by IHG
3.5 star property
6.5 km from South Main
7.8 out of 10, Good, (1,355 reviews)
The price is CNY484
CNY567 total
includes taxes & fees
Feb 16 - Feb 17
Crowne Plaza Houston Med Ctr-Galleria Area by IHG
Presidential Suite, 1 King Bed | Premium bedding, in-room safe, desk, iron/ironing board

DoubleTree by Hilton Hotel Houston - Greenway Plaza

DoubleTree by Hilton Hotel Houston - Greenway Plaza
4.0 star property
6.6 km from South Main
8.4 out of 10, Very Good, (1,464 reviews)
The price is CNY742
CNY868 total
includes taxes & fees
Feb 16 - Feb 17
DoubleTree by Hilton Hotel Houston - Greenway Plaza
Staircase

The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria
4.0 star property
The Galleria, 8.8 km from South Main
8.6 out of 10, Excellent, (1,610 reviews)
The price is CNY927
CNY1,085 total
includes taxes & fees
Feb 13 - Feb 14
The Royal Sonesta Houston Galleria
Outdoor pool, open 6:00 AM to 10:00 PM, pool umbrellas, sun loungers

Hyatt Regency Houston/Galleria

Hyatt Regency Houston/Galleria
4.0 star property
8.7 km from South Main
9.0 out of 10, Wonderful, (1,235 reviews)
The price is CNY1,144
CNY1,347 total
includes taxes & fees
Feb 23 - Feb 24
Hyatt Regency Houston/Galleria
Exterior

Home2 Suites by Hilton at the Galleria

Home2 Suites by Hilton at the Galleria
3.0 star property
Greater Uptown, 8 km from South Main
9.0 out of 10, Wonderful, (1,006 reviews)
The price is CNY742
CNY868 total
includes taxes & fees
Feb 22 - Feb 23
Home2 Suites by Hilton at the Galleria
Serves dinner and happy hour

The Chifley Houston, Tapestry Collection by Hilton

The Chifley Houston, Tapestry Collection by Hilton
4.0 star property
The Galleria, 8.7 km from South Main
9.2 out of 10, Wonderful, (1,256 reviews)
The price is CNY789
CNY923 total
includes taxes & fees
Feb 15 - Feb 16
The Chifley Houston, Tapestry Collection by Hilton
Lobby

Sonesta ES Suites Houston Galleria

Sonesta ES Suites Houston Galleria
3.0 star property
The Galleria, 8.4 km from South Main
8.2 out of 10, Very Good, (1,180 reviews)
The price is CNY641
CNY750 total
includes taxes & fees
Feb 18 - Feb 19
Sonesta ES Suites Houston Galleria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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When is the best time to visit South Main?

Our prices for hotels in South Main are cheapest in February
Price trends for hotels in South Main
Pricing is based on two traveler single night rates
View properties in February
Currently viewing crowd sizes and weather for February.
Typical weather for Houston
February
High 19°C / low 10°C. Cloudy most days.
View properties in February
19°
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February, no crowd data, average high temperature 19 degrees Celsius, average low temperature 10 degrees Celsius. Cloudy most days.
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23°
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March, no crowd data, average high temperature 23 degrees Celsius, average low temperature 14 degrees Celsius. Sunny most days.
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26°
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April, no crowd data, average high temperature 26 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
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30°
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May, no crowd data, average high temperature 30 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
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33°
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June, no crowd data, average high temperature 33 degrees Celsius, average low temperature 24 degrees Celsius. Sunny most days.
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34°
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July, no crowd data, average high temperature 34 degrees Celsius, average low temperature 25 degrees Celsius. Sunny most days.
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34°
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August, no crowd data, average high temperature 34 degrees Celsius, average low temperature 26 degrees Celsius. Sunny most days.
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32°
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September, no crowd data, average high temperature 32 degrees Celsius, average low temperature 23 degrees Celsius. Sunny most days.
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October, no crowd data, average high temperature 28 degrees Celsius, average low temperature 19 degrees Celsius. Sunny most days.
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November, no crowd data, average high temperature 22 degrees Celsius, average low temperature 13 degrees Celsius. Sunny most days.
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18°
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December, no crowd data, average high temperature 18 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
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17°
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January, no crowd data, average high temperature 17 degrees Celsius, average low temperature 8 degrees Celsius. Sunny most days.
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Monthly weather averages (˚C)

Check out reviews of South Main hotels guests love

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

10/10 Excellent
"Clean room and very courteous staff!"
Saleem 3-night trip
Posted 1 day ago
Hilton Houston Plaza/Medical Center

Frequently asked questions

Is South Main expensive to stay in?
You can find great hotels from CNY567 in South Main to suit a range of budgets. To find the best low-cost hotel on Hotels.com that meets your needs, apply your search filters and then sort hotels by "Price: low to high".
How can I find discounted rates and deals for South Main hotels?
Discover great deals on hotels in South Main with Hotels.com. Sign up for free to unlock member only prices and start earning rewards. It's also a good idea to look at hotel prices mid-week or during the low season as you're likely to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on South Main hotels.
Can I receive a refund if I cancel my South Main hotel booking?
The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel your booking. Some South Main hotels require you to cancel more than 24 hours before check-in, so look at your booking beforehand. For extra peace of mind before you book, filter hotels by "Property cancellation options" and select "Fully refundable property".
What are some of the best pet-friendly hotels in South Main?
Traveling with your pet doesn't mean sacrificing a great hotel stay. In South Main, our travelers love:
What are some of the best South Main hotels for couples?
One of the best South Main hotels for couples is Wingate Houston near NRG Park/Medical Center. Wingate Houston near NRG Park/Medical Center is a popular hotel with an outdoor pool. Find more romantic South Main hotels by using the "Traveler experience" filter in your search and selecting "Adults only" or "Romantic".
What are some of the best South Main hotels with a pool?
Book a South Main hotel with a pool for some added relaxation or exercise on your trip. Wyndham Houston near NRG Park/Medical Center is a top-rated hotel with an outdoor pool, and an average guest score of 7.2 out of 10. This hotel also features a restaurant and a bar/lounge. Wingate Houston near NRG Park/Medical Center is another great hotel that features an outdoor pool, along with a free continental breakfast and a gym. For more South Main hotels with a pool, use the "Amenities" filter in your search and select "Pool" on Hotels.com.
Is it worth staying in South Main?
You're spoilt for choice with 64 hotels in the area so it's easy to find your perfect somewhere. Basing yourself in South Main makes it easy to explore Houston, including the neighborhoods of The Galleria and Texas Medical Center.
Which station is best for South Main?
The main station in South Main is Fannin South Station. If you're staying at a hotel in South Main, check out the nearest station so that you can get around and explore with ease.
Find out more about South Main

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