Hotels near Substance Las Vegas

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Where to stay near Substance?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night near Substance on Hotels.com. These hotels close to Substance consistently deliver on quality, location and traveler experience. Last updated on October 14, 2026.

A rooftop lounge with a fire pit, large windows, and a city view.

A modern lobby with a marble coffee table, blue sofas, and a 'Be Our Guest' sign.

A modern hotel room with a large window offering a city view, a comfortable seating area with red and white chairs, and a small table.

A hotel room with a large bed, a blue sofa, a small table, and a view of the city at night.

1. Circa Resort & Casino – Adults Only

Downtown Las Vegas, 0.5 km from Substance

casiano

CNY796

CNY1,278 total

includes taxes & fees

Oct 15 - Oct 16

A storefront with a glass door, a black awning, and a floral archway.

A modern outdoor seating area with wooden furniture and a variety of plants.

A modern outdoor pool area with lounge chairs and sofas, a clear pool, and a building with large windows in the background.

The English Hotel with a rooftop pool, modern architecture, and a view of the city skyline including the Space Needle.

2. The ENGLISH Hotel, Las Vegas, a Tribute Portfolio Hotel, 21 and over

Arts District, 1.4 km from Substance

Sharma

CNY1,439

CNY1,626 total

includes taxes & fees

Oct 25 - Oct 26

A spacious dining area with wooden tables and chairs, ornate ceiling design, and a central decorative piece.

A casino with multiple blackjack tables, slot machines, and a large chandelier.

A grand hotel lobby with a long wooden corridor, ornate chandeliers, and a central decorative fireplace.

A bar area with marble counters, leather chairs, and a red carpet.

3. Main Street Station Hotel, Casino and Brewery

Downtown Las Vegas, 0.6 km from Substance

Stewart

CNY187

CNY461 total

includes taxes & fees

Oct 28 - Oct 29

A bar area with a leather couch, red chairs, and a bar counter.

A bar area with a round bar, multiple chandeliers, and a variety of seating options.

An outdoor dining area with tables and chairs, umbrellas, and candles.

A modern interior with a round table, chairs, and a decorative vase with flowers.

4. Downtown Grand Las Vegas

Downtown Las Vegas, 0.2 km from Substance

Richard

CNY313

CNY648 total

includes taxes & fees

Nov 1 - Nov 2

A modern reception desk with vertical light fixtures and a marble counter.

A modern lounge area with a sectional sofa, round tables, and chairs. Large windows offer views of the outdoors.

A modern interior with round tables and green chairs, wooden shelves with decorative items, and large windows offering a view.

A hotel with a modern facade, large signage for Marriott and Element brands, and a prominent entrance with a palm tree in the foreground.

5. Element by Marriott Las Vegas Symphony Park

1.2 km from Substance

Jennifer

CNY1,044

CNY1,347 total

includes taxes & fees

Nov 8 - Nov 9

A hotel room with a large bed, a desk, a chair, a lamp, and a window with curtains.

A spacious lobby with a grand reception desk, multiple floors, and a modern chandelier design.

A bar area with multiple seating options, including bar stools and tables, and a brick wall with neon signage.

A bar area with multiple gaming machines, a bar counter, and several bar stools.

6. Four Queens Hotel and Casino

Downtown Las Vegas, 0.3 km from Substance

David

CNY462

CNY522 total

includes taxes & fees

Oct 27 - Oct 28

An outdoor seating area with a wooden bench, a table with food, potted plants, and a view of the building's interior through a glass door.

A modern lobby with seating, a reception desk, and a decorative wall.

A modern interior with seating, a large flat-screen TV, and a view through large windows.

A hotel with a modern facade, palm trees, and a distinctive wall with circular patterns.

7. AC Hotel by Marriott Las Vegas Symphony Park

1.2 km from Substance

Sarah

CNY819

CNY1,093 total

includes taxes & fees

Oct 18 - Oct 19

A brick-walled interior with a wooden floor and a black metal railing.

A hotel room with a bed, a desk, a chair, a bathroom with a mirror, and a view of the city.

A corner room with two leather chairs, a small table with a vase of flowers, and a large window offering a cityscape view.

8. the D Las Vegas

Downtown Las Vegas, 0.2 km from Substance

Adan

CNY194

CNY521 total

includes taxes & fees

Oct 15 - Oct 16

A spacious lobby with a stone floor, wooden beams, and a large chandelier.

A bar area with multiple screens, bar stools, and a central bar counter.

A well-lit food court with a variety of food options, seating areas, and a counter with beverages.

A lobby with a grand staircase, a bar area, and multiple gaming machines.

9. El Cortez Hotel and Casino - 21 and Over

Downtown Las Vegas, 0.2 km from Substance

Juana rosa

CNY256

CNY516 total

includes taxes & fees

Nov 12 - Nov 13

A bar with wooden furniture and a television displaying a sports event.

A restaurant with tables set for dining, a city view, and a large window.

A modern bar area with multiple seating arrangements, a wooden bar counter, and several screens displaying content.

A restaurant with a view of a neon-lit building and a large screen displaying an image of a person.

10. Hotel Apache

Downtown Las Vegas, 0.4 km from Substance

Alan

CNY361

CNY408 total

includes taxes & fees

Oct 28 - Oct 29

A hotel with a large indoor pool, palm trees, and a modern building in the background.

A modern living room with a curved staircase, a sofa set, and a view of the cityscape through large windows.

A bar area with a large aquarium, bar stools, and a decorative railing.

A hotel with a pool area, outdoor seating, and a view of the city skyline at night.

11. Golden Nugget Las Vegas Hotel & Casino

Downtown Las Vegas, 0.4 km from Substance

Steven

CNY264

CNY647 total

includes taxes & fees

Oct 15 - Oct 16

A large, modern steakhouse with a curved roof and multiple dining areas, surrounded by other buildings.

A swimming pool with lounge chairs and a building with a large mural in the background.

A spacious indoor area with a registration desk, a coffee bar, and a gelato display.

A multi-story building with a prominent sign reading "Plaza Hotel Casino Bingo" and a carousel at the ground level.

12. Plaza Hotel & Casino

Downtown Las Vegas, 0.6 km from Substance

MAIKER

CNY241

CNY567 total

includes taxes & fees

Nov 11 - Nov 12

A bar area with multiple stools and tables, a well-stocked bar counter, and framed signs on the wall.

A casino with multiple blackjack tables, slot machines, and a cashier area.

A gym with exercise equipment, including treadmills and weight machines.

A hotel room with two beds, a bedside table with a lamp, a telephone, and artwork on the walls.

13. Fremont Hotel & Casino

Downtown Las Vegas, 0.3 km from Substance

Gloria

CNY258

CNY548 total

includes taxes & fees

Oct 28 - Oct 29

A hotel room with two beds, a desk, a chair, a large mirror, and a decorative wall with geometric patterns.

A bar area with a blue wall, white chairs, and a bar counter.

A bar area with white chairs, a wooden counter, and a vending machine labeled "Goodies".

A wall with a colorful mural reading "Greetings From Downtown Las Vegas Nevada."

14. Downtowner Boutique Hotel

Downtown Las Vegas, 0.4 km from Substance

Isabel

CNY235

CNY417 total

includes taxes & fees

Nov 11 - Nov 12

A nighttime view of a pool area with a city skyline in the background, including a prominent tower.

A hotel corridor with wicker furniture and orange cushions, a yellow door, and a balcony with railings.

Two wooden beds with white linens, a wooden headboard, a bedside lamp, and a framed picture on the wall.

A compact living space with bunk beds, a wooden dining table, and a kitchen area in the background.

15. Bposhtels Las Vegas

1.8 km from Substance

Dshanick

CNY163

CNY260 total

includes taxes & fees

Oct 19 - Oct 20

A modern hotel room with two beds, a desk, a mirror, and a shower area.

A swimming pool with lounge chairs and umbrellas, surrounded by palm trees and tall buildings.

A fitness center with treadmills, a wall-mounted TV, and a rack of dumbbells.

A modern kitchen with a built-in oven, a sink, and a countertop.

16. Oasis at Gold Spike

Downtown Las Vegas, < 0.1 km from Substance

Dearld

CNY295

CNY523 total

includes taxes & fees

Oct 20 - Oct 21

A hotel with a prominent tower and the name "STRAT" illuminated on the facade.

A building with a sign reading "ATOMIC GOLF" and a large illuminated spherical sculpture in front.

A restaurant setting with a table set for dining, a city view in the background, and a sunset over the mountains.

A modern bar area with a long counter, bar stools, and a seating area with couches and tables.

17. The STRAT Hotel, Casino & Tower

Las Vegas Strip, 2.9 km from Substance

Juan

CNY90

CNY481 total

includes taxes & fees

Nov 9 - Nov 10

The exterior of the Golden Gate Hotel with a prominent sign, a modern architectural design, and a parking lot with visible cars.

A hotel lobby with a large black carpet, a wall with 'GOLDEN GATE' signage, and a row of vintage arcade machines.

A hotel room with a large bed, a leather sofa, a TV, a minibar, and a city view.

The exterior of the Golden Gate Hotel & Casino with a bar area featuring a variety of liquor bottles.

18. Golden Gate Hotel and Casino

Downtown Las Vegas, 0.5 km from Substance

Talaleu

CNY161

CNY484 total

includes taxes & fees

Oct 20 - Oct 21

A hotel room with a large bed, a bedside table, a chair, a desk, and a mirror.

A covered outdoor corridor with green doors, a blue floor, and a view of a parking lot and trees.

A compact kitchenette with a microwave, a small table, and a chair.

A compact kitchen with a microwave and cabinet, a dining table with a chair, and a hanging coat rack.

19. Crown Motel

Sunrise Manor, 3.1 km from Substance

Robert

CNY897

CNY1,081 total

includes taxes & fees

Oct 19 - Oct 20

An outdoor seating area with wicker furniture, palm trees, and a clear sky.

A bar area with a long counter, multiple bar stools, and various bar equipment.

A spacious indoor area with multiple seating arrangements including couches and tables, exposed ductwork, and hanging pendant lights.

A wooden bed with a headboard, two bedside tables with lamps, and a patterned rug.

20. Thunderbird Hotel

Gateway District, 1.8 km from Substance

Tara

CNY262

CNY425 total

includes taxes & fees

Nov 1 - Nov 2

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Compare popular hotels close to Substance

Property	Property class	Guest rating
Circa Resort & Casino – Adults Only	9.4 Exceptional 5,723 reviews	View
The ENGLISH Hotel, Las Vegas, a Tribute Portfolio Hotel, 21 and over	9.4 Exceptional 154 reviews	View
Main Street Station Hotel, Casino and Brewery	9.0 Wonderful 3,884 reviews	View
Downtown Grand Las Vegas	8.6 Excellent 9,997 reviews	View
Element by Marriott Las Vegas Symphony Park	9.0 Wonderful 156 reviews	View

Other landmarks near Substance

Neonopolis

If museums are on your list, you might want to check out the upcoming exhibitions at Neonopolis in Downtown Las Vegas. It's also full of great shops and restaurants, so you can spend the afternoon having a wander. If you want to see more of the museums in Las Vegas, you can easily walk to Mob Museum.

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A large indoor amusement ride with a digital display of a cityscape.

SlotZilla Zipline

Downtown Las Vegas is home to SlotZilla Zipline, so why not stop by during your stay in Las Vegas. Las Vegas has other popular activities such as Allegiant Stadium.

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The Nerd

If you find yourself in Downtown Las Vegas, you can stop off for a few drinks or snacks at The Nerd.

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Fremont Street Flightlinez

Why not give yourself a treat with a trip to Fremont Street Flightlinez, just one of the family attractions in central Las Vegas. Let yourself be amazed at the museums in the area— your cultural tour starts here. It's also full of great shops and restaurants, so you can spend the afternoon having a wander. If you have fun at Fremont Street Flightlinez, you'll love Fergusons Downtown, just a short walk away.

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The Griffin

If you find yourself in Downtown Las Vegas, you can stop off for a few drinks or snacks at The Griffin.

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We All Scream

If the club scene floats your boat, dance the night away at We All Scream in Downtown Las Vegas.

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Backstage & Billiards Lounge

If the club scene floats your boat, dance the night away at Backstage & Billiards Lounge in Downtown Las Vegas.

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LIV Beach at Fontainebleau Las Vegas

LIV Beach at Fontainebleau Las Vegas is a venue in Downtown Las Vegas.

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Frequently asked questions

What are the best hotels near Substance?

Guests love staying at the D Las Vegas, which is a hotel near Substance.
Another highly rated hotel is Downtown Grand Las Vegas, which is just steps away.
With 9,178 hotels, vacation rentals, and other accommodations in the area, you'll have plenty to choose from.

How much does it cost to stay in a hotel near Substance?

You can review prices on Hotels.com by entering your search criteria and sorting by price. Remember that rates vary based on where and when you plan to go.

Take a look at the lowest price per night from CNY260

What cheap hotels are close to Substance?

For a wallet-friendly hotel close to Substance, take a look at Fremont Hotel & Casino, which offers a casino, 8 restaurants, and 4 bars/lounges.
Another low-cost alternative is Super 8 by Wyndham Las Vegas North Strip/Fremont St. Area, which is a short drive away.

Can I find hotels close to Substance that are fully refundable?

Yes, you'll find many hotels that offer refundable room rates as long as you cancel by the cancellation deadline. Find refundable rates using the "Fully refundable" filter when you search for hotels.

A couple of highly rated hotels near Substance that offer these rates are Fontainebleau Las Vegas, MICHELIN Key Award Hotel and Crockfords Las Vegas, LXR Hotels & Resorts at Resorts World.

What are the best romantic hotels near Substance?

If you are looking for a romantic stay, the D Las Vegas offers 3 restaurants, an outdoor pool, and 3 bars/lounges. It's steps from Substance.
Another great option is Golden Nugget Las Vegas Hotel & Casino, which is just steps away.

What are the best hotels close to Substance with free breakfast?

Begin your day with a free continental breakfast at Element by Marriott Las Vegas Symphony Park, which is a short 3-minute drive from Substance.
The Palazzo Prestige Club Lounge is also a recommended place to stay with a free continental breakfast, and it's located a short drive away.

Which hotels near Substance have rooms with great views?

Enjoy rooms with city or pool views at Oasis at Gold Spike, which is steps from Substance.
Also recommended is the D Las Vegas, which has rooms with city or mountain views.

What are the best family hotels close to Substance?

Keep the family happy with a stay at the D Las Vegas which offers free cribs and an outdoor pool. Substance is just steps away.
Another great option for your family's trip is Element by Marriott Las Vegas Symphony Park.

What are the best luxury hotels near Substance?

Pamper yourself with a stay at Circa Resort & Casino – Adults Only, which is a short walk from Substance. This hotel features 5 restaurants including Barry's Downtown Prime, and offers 6 outdoor pools.
A second luxurious choice is Las Vegas Hilton at Resorts World, which is a short drive away.

What are the best hotels near Substance with free parking?

Travelers looking to drive and park with ease should consider a stay at Downtowner Boutique Hotel, which offers free parking. You'll be steps from Substance.
Downtown Grand Las Vegas also has free parking and is just steps away.

What are the best hotels near Substance with a pool?

If swimming is at the top of your list, the D Las Vegas has an outdoor pool. Substance is steps from the hotel.
Another great choice for a hotel with a pool is Downtown Grand Las Vegas.

What cheap motels can I book close to Substance?

To stay economically near Substance, you can book Downtowner Boutique Hotel, which offers an outdoor pool and a bar/lounge.
Also consider Desert Moon Motel, which is another inexpensive motel in the area.

What are the best things to see and do around my hotel near Substance?

You can see top attractions like Colosseum at Caesars Palace, Fremont Street Experience, and Allegiant Stadium during your stay near Substance.
Other popular places in the area are Excalibur Casino, Las Vegas Festival Grounds, and Sphere.

What are the best pet-friendly hotels close to Substance?

Bring your four-legged friend to Downtown Grand Las Vegas, which is steps from Substance.
Another pet-friendly spot is Golden Nugget Las Vegas Hotel & Casino. The resort offers an off-leash area.