Hotels in St. Charles

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Dates

September 2025

October 2025

Free cancellation options if plans change

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Tonight

Tomorrow

Next weekend

In two weeks

Where to stay in St. Charles?

CNY549 total

includes taxes & fees

Oct 20 - Oct 21

CNY830 total

includes taxes & fees

Oct 18 - Oct 19

CNY591 total

includes taxes & fees

Oct 5 - Oct 6

CNY568 total

includes taxes & fees

Oct 12 - Oct 13

CNY677 total

includes taxes & fees

Oct 19 - Oct 20

CNY662 total

includes taxes & fees

Oct 12 - Oct 13

CNY426 total

includes taxes & fees

Oct 3 - Oct 4

CNY455 total

includes taxes & fees

Oct 4 - Oct 5

CNY1,142 total

includes taxes & fees

Oct 3 - Oct 4

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Go beyond your typical stay in St. Charles

Hot tub

Pool

Check out reviews of St. Charles hotels guests love

Med City Inn & Suites - Mayo Clinic Area

10/10 Excellent

"Great choice for Mayo patients"

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

10/10 Excellent

"The room was clean. The shower did have some spots that needed to be cleaned better and tile work was attempted to be fixed, but not done the best. Breakfast was so-so. They served biscuits and gravy and it didn't seem fresh. There was a small container of what seemed to be left over of the gravy. No fruit options. "

Frequently asked questions

What accommodations do travelers recommend in St. Charles?

White Valley Motel is an accommodation that is popular with guests.

Can I book refundable accommodations in St. Charles?

If you need the flexibility to change your plans to St. Charles, most properties provide refundable* bookable rates. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in St. Charles be like during my vacation?

July and August are typically the warmest months in St. Charles when the average temp is 67°F. January and February are the coldest months when the average temperature is 22°F. June and May are the months with the most rain.

Why should I book my St. Charles accommodation with Hotels.com?

There are plenty of reasons to book your St. Charles travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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Hotels in St. Charles

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Where to stay in St. Charles?

White Valley Motel

White Valley Motel

Go beyond your typical stay in St. Charles

Check out reviews of St. Charles hotels guests love

Med City Inn & Suites - Mayo Clinic Area

Frequently asked questions

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