Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Poplar Bluff on Hotels.com. These Poplar Bluff hotels consistently deliver on quality, location and traveler experience. Last updated on .
Hotels in Poplar Bluff
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Where to stay in Poplar Bluff?




1. Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar Bluff



2. Drury Inn & Suites Poplar Bluff
Drury Inn & Suites Poplar Bluff



3. Hampton Inn Poplar Bluff
Hampton Inn Poplar Bluff



4. Holiday Inn Poplar Bluff by IHG
Holiday Inn Poplar Bluff by IHG



5. Motel 6 Poplar Bluff, MO
Motel 6 Poplar Bluff, MO



6. Comfort Inn Poplar Bluff North
Comfort Inn Poplar Bluff North



7. Super 8 by Wyndham Poplar Bluff Missouri
Super 8 by Wyndham Poplar Bluff Missouri



8. 40-acre Poplar Bluff Nature Lovers Paradise!
40-acre Poplar Bluff Nature Lovers Paradise!



9. Hampton Inn By Hilton Dexter
Hampton Inn By Hilton Dexter



10. Travelodge by Wyndham Dexter
Travelodge by Wyndham Dexter



11. Lake Wappapello
Lake Wappapello



12. Econo Lodge Dexter
Econo Lodge Dexter



14. OYO Hickory House Inn
OYO Hickory House InnGet last-minute hotel deals in Poplar Bluff and save more




Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar Bluff



Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar Bluff



Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffCheck out pet-friendly hotels in Poplar Bluff




40-acre Poplar Bluff Nature Lovers Paradise!
40-acre Poplar Bluff Nature Lovers Paradise!You may also like hotels with pools in Poplar Bluff




Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffGo beyond your typical stay in Poplar Bluff
Our prices for hotels in Poplar Bluff are cheapest in January
Price trends for hotels in Poplar Bluff
Top landmarks in Poplar Bluff
Black River Coliseum
Mo-Ark Regional Railroad Museum
Margaret Harwell Art Museum
North Main Street Historic District
Ozark Ridge Golf Course
Poplar Bluff History Museum
Learn more about Poplar Bluff
Discover a slice of Americana where the Gateway to the Ozarks reveals its treasures. The Margaret Harwell Art Museum showcases local talent while the Mo-Ark Regional Railroad Museum delights train enthusiasts with its historical collections. Kayak the Black River's gentle currents or cast a line at Lake Wappapello, where fishing spots seem plucked from a Norman Rockwell painting. The North Main Street Historic District offers antique shops and local eateries housed in brick buildings that have witnessed generations of small-town life. Hikers find solace in the nearby Mark Twain National Forest, where trails wind through Ozark wilderness. Don't miss the Ozark Ridge Golf Course, where fairways unfold against rolling hills that explain why locals never seem in a hurry to leave.
See all hotels in Poplar Bluff
Check out reviews of Poplar Bluff hotels guests love
Hampton Inn Poplar Bluff
"Clean rooms, efficient staff, lovely breakfast. I appreciated the hotel sending a text after I checked in; it made it very easy to get questions answered."
Drury Inn & Suites Poplar Bluff
"Our room was very clean and smelled fresh. The hotel was also very clean and tidy. The staff were friendly and the buffet breakfast was great quality. We love Drury Hotels ❤️"
Fairfield Inn & Suites by Marriott Poplar Bluff
"Great staff, clean and spacious room and bathroom, great morning breakfast"
Holiday Inn Poplar Bluff by IHG
"Debbie at the front desk is perfect."
Motel 6 Poplar Bluff, MO
"Terrific base accommodation. Clean, efficient. I use this place whenever I’m in the area. I’m"
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