Hotels in Poplar Bluff

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Oct 10 - Oct 11

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Next weekend

Oct 16 - Oct 18

Where to stay in Poplar Bluff?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Poplar Bluff on Hotels.com. These Poplar Bluff hotels consistently deliver on quality, location and traveler experience. Last updated on October 9, 2026.

A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and large windows providing natural light.

Snack bar

Exterior

Pool

1. Hampton Inn Poplar Bluff

Poplar Bluff

CNY610

CNY683 total

includes taxes & fees

Oct 18 - Oct 19

A modern lounge area with a stone fireplace, blue seating, a round coffee table, and a large window offering a view.

An outdoor patio with a table and chairs, a large umbrella, and a glass door leading to an interior space.

A reception area with a wooden counter, a coffee machine, and a display of pastries.

A reception desk with a bicycle light, potted plants, and a 'Connect & Print' sign.

2. Fairfield Inn & Suites by Marriott Poplar Bluff

Poplar Bluff

CNY650

CNY734 total

includes taxes & fees

Oct 18 - Oct 19

A spacious lobby with a reception desk, seating area, and large windows.

A spacious lobby with a high ceiling, a mezzanine level, and a seating area with a sofa and chairs.

A hotel room with a bed, a desk, a chair, a sofa, and a TV.

An indoor swimming pool with a clear view of the outside through large windows.

3. Drury Inn & Suites Poplar Bluff

Poplar Bluff

CNY630

CNY712 total

includes taxes & fees

Oct 29 - Oct 30

A hotel room with a sofa, a small table, a chair, a desk, two lamps, a window with curtains, and a framed picture on the wall.

A Holiday Inn hotel with a covered entrance, multiple flags, and a brick facade.

A hotel room with a desk, chair, and a small seating area. It includes a microwave, coffee maker, and a refrigerator.

Pool

4. Holiday Inn Poplar Bluff by IHG

Poplar Bluff

CNY530

CNY598 total

includes taxes & fees

Nov 8 - Nov 9

A modern kitchen with a coffee machine, a sink, and a counter. There are four chairs and a table in the dining area.

A hotel room with two beds, a desk, a chair, a TV mounted on the wall, and a mirror.

A compact kitchen with a dark wooden desk, a black refrigerator, a microwave, and a coffee maker.

A motel with a prominent '66' sign, large windows, and a flat roof.

5. Motel 6 Poplar Bluff, MO

Poplar Bluff

CNY477

CNY534 total

includes taxes & fees

Oct 23 - Oct 24

A hotel lobby with a reception desk, a blue sofa, a fireplace, and a television.

A hotel room with a bed, two armchairs, a sofa, a small table, a TV, a ceiling fan, and a window with curtains.

A hotel with a covered entrance, multiple windows, and a yellow facade.

A hotel lobby with a coffee station, seating area, and a television screen.

6. Comfort Inn Poplar Bluff North

Poplar Bluff

CNY497

CNY561 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a bed, two bedside lamps, a framed picture of a building, and a nightstand with a phone.

A self-service breakfast area with a refrigerated drink cooler, a coffee machine, and various food items on the counter.

A lobby with a reception desk, a Coca-Cola vending machine, a snack vending machine, and a seating area with a round table.

A two-story motel with a covered parking area and a bench outside.

7. Super 8 by Wyndham Poplar Bluff Missouri

Poplar Bluff

CNY450

CNY509 total

includes taxes & fees

Oct 15 - Oct 16

A spacious living area with a dark grey sofa set, a matching ottoman, and a wooden-paneled wall.

A two-story house with a deck and a covered porch.

A room with wooden paneling, a ceiling fan, a dining table with chairs, and a sofa.

A house with a red door, a porch with rocking chairs, and a wreath on the door.

8. 40-acre Poplar Bluff Nature Lovers Paradise!

Poplar Bluff

CNY804

CNY1,990 total

includes taxes & fees

Oct 21 - Oct 22

A modern hotel lobby with a bar area, seating, and artwork on the walls.

A modern kitchen with a large island, bar stools, wine bottles, and a built-in TV.

A swimming pool with clear blue water, surrounded by sun loungers and a lifeguard stand.

A modern hotel with a prominent sign, a covered entrance, and a well-lit exterior.

9. Hampton Inn By Hilton Dexter

Dexter

CNY654

CNY741 total

includes taxes & fees

Oct 25 - Oct 26

A diner with booth seating, a checkered floor, and a counter with a cash register.

A lobby with a round rug, two potted plants, three framed artworks, and two black leather chairs.

A reception area with a marble counter, potted plants, a clock, and a TV on the wall.

A gym with multiple exercise machines, a clock on the wall, and a window with blinds.

10. Travelodge by Wyndham Dexter

Dexter

CNY579

CNY656 total

includes taxes & fees

Oct 25 - Oct 26

A rustic cabin with a metal roof, surrounded by a wooden deck and picnic tables, set in a forested area.

A bedroom with a wooden bed, a bench, and a window.

A wooden deck with a railing leading to a building with a metal roof and a brown door.

Front of property

11. Lake Wappapello

Williamsville

CNY603

CNY636 total

includes taxes & fees

Oct 10 - Oct 11

A hotel room with a bed, a desk, a chair, a bathroom with a bathtub, and a patterned floor.

A living room with a sofa, a coffee table, a clock, and a painting on the wall.

A kitchen with wooden cabinets, a stainless steel sink, a microwave, and a dishwasher.

A hotel reception area with a reception desk, framed certificates, and a painting on the wall.

12. Econo Lodge Dexter

Dexter

CNY342

CNY387 total

includes taxes & fees

Nov 7 - Nov 8

A coffee shop with a coffee machine, espresso cups, a sink, and a trash bin.

A hotel hallway with patterned carpet, light green walls, and a ceiling with recessed lighting.

A hotel room with two beds, a desk with a lamp, a chair, a dresser, and a door with a handle.

A kitchen with a white microwave, a fruit basket, a coffee maker, and a storage container.

13. Dexter Inn

Dexter

CNY463

CNY524 total

includes taxes & fees

Oct 10 - Oct 11

A hotel room with two beds, a TV, a mirror, a wardrobe, and a desk.

A window with a view of a parking lot and buildings, a welcome sign, and a credit card machine.

A bathroom with a bathtub, toilet, and a shower curtain.

A Hickory House Inn with a clear sky, a parking lot, and a covered entrance.

14. OYO Hickory House Inn

Dexter

CNY369

CNY455 total

includes taxes & fees

Oct 23 - Oct 24

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A modern kitchen with a coffee machine, a sink, and a counter. There are four chairs and a table in the dining area.

A hotel room with two beds, a desk, a chair, a TV mounted on the wall, and a mirror.

A compact kitchen with a dark wooden desk, a black refrigerator, a microwave, and a coffee maker.

A motel with a prominent '66' sign, large windows, and a flat roof.

Motel 6 Poplar Bluff, MO

Poplar Bluff

CNY550

per night

CNY615 total

includes taxes & fees

A spacious lobby with a reception desk, seating area, and large windows.

A spacious lobby with a high ceiling, a mezzanine level, and a seating area with a sofa and chairs.

A hotel room with a bed, a desk, a chair, a sofa, and a TV.

An indoor swimming pool with a clear view of the outside through large windows.

Drury Inn & Suites Poplar Bluff

Poplar Bluff

We have 7 left at

CNY945

per night

CNY1,068 total

includes taxes & fees

A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and large windows providing natural light.

Snack bar

Exterior

Pool

Hampton Inn Poplar Bluff

Poplar Bluff

CNY999

per night

CNY1,118 total

includes taxes & fees

A hotel room with a sofa, a small table, a chair, a desk, two lamps, a window with curtains, and a framed picture on the wall.

A Holiday Inn hotel with a covered entrance, multiple flags, and a brick facade.

A hotel room with a desk, chair, and a small seating area. It includes a microwave, coffee maker, and a refrigerator.

Pool

Holiday Inn Poplar Bluff by IHG

Poplar Bluff

We have 2 left at

CNY898

per night

CNY1,015 total

includes taxes & fees

A hotel room with a bed, two bedside lamps, a framed picture of a building, and a nightstand with a phone.

A self-service breakfast area with a refrigerated drink cooler, a coffee machine, and various food items on the counter.

A lobby with a reception desk, a Coca-Cola vending machine, a snack vending machine, and a seating area with a round table.

A two-story motel with a covered parking area and a bench outside.

Super 8 by Wyndham Poplar Bluff Missouri

Poplar Bluff

We have 1 left at

CNY550

per night

CNY621 total

includes taxes & fees

A hotel lobby with a reception desk, a blue sofa, a fireplace, and a television.

A hotel room with a bed, two armchairs, a sofa, a small table, a TV, a ceiling fan, and a window with curtains.

A hotel with a covered entrance, multiple windows, and a yellow facade.

A hotel lobby with a coffee station, seating area, and a television screen.

Comfort Inn Poplar Bluff North

Poplar Bluff

CNY902

per night

CNY1,019 total

includes taxes & fees

A modern lounge area with a stone fireplace, blue seating, a round coffee table, and a large window offering a view.

An outdoor patio with a table and chairs, a large umbrella, and a glass door leading to an interior space.

A reception area with a wooden counter, a coffee machine, and a display of pastries.

A reception desk with a bicycle light, potted plants, and a 'Connect & Print' sign.

Fairfield Inn & Suites by Marriott Poplar Bluff

Poplar Bluff

A modern kitchen with a coffee machine, a sink, and a counter. There are four chairs and a table in the dining area.

A hotel room with two beds, a desk, a chair, a TV mounted on the wall, and a mirror.

A compact kitchen with a dark wooden desk, a black refrigerator, a microwave, and a coffee maker.

A motel with a prominent '66' sign, large windows, and a flat roof.

Motel 6 Poplar Bluff, MO

Poplar Bluff

CNY550

per night

CNY615 total

includes taxes & fees

A modern lounge area with a stone fireplace, blue seating, a round coffee table, and a large window offering a view.

An outdoor patio with a table and chairs, a large umbrella, and a glass door leading to an interior space.

A reception area with a wooden counter, a coffee machine, and a display of pastries.

A reception desk with a bicycle light, potted plants, and a 'Connect & Print' sign.

Fairfield Inn & Suites by Marriott Poplar Bluff

Poplar Bluff

We have 1 left at

CNY831

per night

CNY939 total

includes taxes & fees

A hotel room with a bed, two bedside lamps, a framed picture of a building, and a nightstand with a phone.

A self-service breakfast area with a refrigerated drink cooler, a coffee machine, and various food items on the counter.

A lobby with a reception desk, a Coca-Cola vending machine, a snack vending machine, and a seating area with a round table.

A two-story motel with a covered parking area and a bench outside.

Super 8 by Wyndham Poplar Bluff Missouri

Poplar Bluff

We have 1 left at

CNY495

per night

CNY559 total

includes taxes & fees

A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and large windows providing natural light.

Snack bar

Exterior

Pool

Hampton Inn Poplar Bluff

Poplar Bluff

CNY999

per night

CNY1,118 total

includes taxes & fees

A spacious lobby with a reception desk, seating area, and large windows.

A spacious lobby with a high ceiling, a mezzanine level, and a seating area with a sofa and chairs.

A hotel room with a bed, a desk, a chair, a sofa, and a TV.

An indoor swimming pool with a clear view of the outside through large windows.

Drury Inn & Suites Poplar Bluff

Poplar Bluff

CNY979

per night

CNY1,106 total

includes taxes & fees

A hotel room with a sofa, a small table, a chair, a desk, two lamps, a window with curtains, and a framed picture on the wall.

A Holiday Inn hotel with a covered entrance, multiple flags, and a brick facade.

A hotel room with a desk, chair, and a small seating area. It includes a microwave, coffee maker, and a refrigerator.

Pool

Holiday Inn Poplar Bluff by IHG

Poplar Bluff

We have 5 left at

CNY898

per night

CNY1,015 total

includes taxes & fees

A hotel lobby with a reception desk, a blue sofa, a fireplace, and a television.

A hotel room with a bed, two armchairs, a sofa, a small table, a TV, a ceiling fan, and a window with curtains.

A hotel with a covered entrance, multiple windows, and a yellow facade.

A hotel lobby with a coffee station, seating area, and a television screen.

Comfort Inn Poplar Bluff North

Poplar Bluff

CNY826

per night

CNY933 total

includes taxes & fees

A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and large windows providing natural light.

Snack bar

Exterior

Pool

Hampton Inn Poplar Bluff

Poplar Bluff

CNY683

per night

CNY1,529 total

includes taxes & fees

A modern lounge area with a stone fireplace, blue seating, a round coffee table, and a large window offering a view.

An outdoor patio with a table and chairs, a large umbrella, and a glass door leading to an interior space.

A reception area with a wooden counter, a coffee machine, and a display of pastries.

A reception desk with a bicycle light, potted plants, and a 'Connect & Print' sign.

Fairfield Inn & Suites by Marriott Poplar Bluff

Poplar Bluff

We have 1 left at

CNY707

per night

CNY1,596 total

includes taxes & fees

A spacious lobby with a reception desk, seating area, and large windows.

A spacious lobby with a high ceiling, a mezzanine level, and a seating area with a sofa and chairs.

A hotel room with a bed, a desk, a chair, a sofa, and a TV.

An indoor swimming pool with a clear view of the outside through large windows.

Drury Inn & Suites Poplar Bluff

Poplar Bluff

We have 1 left at

CNY744

per night

CNY1,681 total

includes taxes & fees

A hotel room with a sofa, a small table, a chair, a desk, two lamps, a window with curtains, and a framed picture on the wall.

A Holiday Inn hotel with a covered entrance, multiple flags, and a brick facade.

A hotel room with a desk, chair, and a small seating area. It includes a microwave, coffee maker, and a refrigerator.

Pool

Holiday Inn Poplar Bluff by IHG

Poplar Bluff

CNY660

per night

CNY1,492 total

includes taxes & fees

A modern kitchen with a coffee machine, a sink, and a counter. There are four chairs and a table in the dining area.

A hotel room with two beds, a desk, a chair, a TV mounted on the wall, and a mirror.

A compact kitchen with a dark wooden desk, a black refrigerator, a microwave, and a coffee maker.

A motel with a prominent '66' sign, large windows, and a flat roof.

Motel 6 Poplar Bluff, MO

Poplar Bluff

CNY530

per night

CNY1,186 total

includes taxes & fees

A hotel lobby with a reception desk, a blue sofa, a fireplace, and a television.

A hotel room with a bed, two armchairs, a sofa, a small table, a TV, a ceiling fan, and a window with curtains.

A hotel with a covered entrance, multiple windows, and a yellow facade.

A hotel lobby with a coffee station, seating area, and a television screen.

Comfort Inn Poplar Bluff North

Poplar Bluff

CNY612

per night

CNY1,383 total

includes taxes & fees

A hotel room with a bed, two bedside lamps, a framed picture of a building, and a nightstand with a phone.

A self-service breakfast area with a refrigerated drink cooler, a coffee machine, and various food items on the counter.

A lobby with a reception desk, a Coca-Cola vending machine, a snack vending machine, and a seating area with a round table.

A two-story motel with a covered parking area and a bench outside.

Super 8 by Wyndham Poplar Bluff Missouri

Poplar Bluff

We have 1 left at

CNY450

per night

CNY1,017 total

includes taxes & fees

Go beyond your typical stay in Poplar Bluff

Family friendly

Pet friendly

Pool

Our prices for hotels in Poplar Bluff are cheapest in January

Top landmarks in Poplar Bluff

Black River Coliseum

8.2/10 (30 reviews)

Black River Coliseum is in the heart of Poplar Bluff, so why not stop by during your stay.

Mo-Ark Regional Railroad Museum

6.8/10 (13 reviews)

The center of Poplar Bluff is home to cultural attractions like Mo-Ark Regional Railroad Museum, so you might want to stop by during your stay. If you want to experience more of the culture Poplar Bluff has to offer, head to Black River Coliseum, Poplar Bluff Regional Medical Center, and Margaret Harwell Art Museum.

Margaret Harwell Art Museum

5.8/10 (8 reviews)

The center of Poplar Bluff is home to cultural attractions like Margaret Harwell Art Museum, so you might want to stop by during your stay. If you want to experience more of the culture Poplar Bluff has to offer, head to Black River Coliseum, Mo-Ark Regional Railroad Museum, and Poplar Bluff Regional Medical Center.

Ozark Ridge Golf Course

7.4/10 (3 reviews)

You might want to play some rounds at Ozark Ridge Golf Course, located 3 mi (4.9 km) from central Poplar Bluff.

North Main Street Historic District

If you're planning a bit of sightseeing during your trip, head to North Main Street Historic District— just one of the monuments in central Poplar Bluff.

Poplar Bluff History Museum

Poplar Bluff History Museum is 0.8 mi (1.3 km) from central Poplar Bluff, why not stop by during your stay. If you want to experience more of the culture Poplar Bluff has to offer, head to Black River Coliseum, Mo-Ark Regional Railroad Museum, and Poplar Bluff Regional Medical Center.

Learn more about Poplar Bluff

Discover a slice of Americana where the Gateway to the Ozarks reveals its treasures. The Margaret Harwell Art Museum showcases local talent while the Mo-Ark Regional Railroad Museum delights train enthusiasts with its historical collections. Kayak the Black River's gentle currents or cast a line at Lake Wappapello, where fishing spots seem plucked from a Norman Rockwell painting. The North Main Street Historic District offers antique shops and local eateries housed in brick buildings that have witnessed generations of small-town life. Hikers find solace in the nearby Mark Twain National Forest, where trails wind through Ozark wilderness. Don't miss the Ozark Ridge Golf Course, where fairways unfold against rolling hills that explain why locals never seem in a hurry to leave.

See all hotels in Poplar Bluff

A historical marker sign for the Frisco Depot, detailing its construction in 1928, architectural style, and historical significance.

Check out reviews of Poplar Bluff hotels guests love

Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

8/10 Good

"Staff very helpful"

Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG

10/10 Excellent

"It was nice and peaceful! Desk clerk was so nice checking and out! Enjoyed my stay! Is close to shopping and dining! Close to the freeway!"

Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff

8/10 Good

"This is the 4th time I have stayed here. The main draw for me is the ability to charge my electric vehicle on the property. Otherwise, the hotel doesn't offer much that can't be found elsewhere at a lower price. The breakfast is standard fare, the room was missing a foldable luggage stand, no garment hook on back of bathroom door, adjustments for shower head didn't work, tub stopper was broken, shower was missing body wash pump container, wallpaper had water damage around tub, some mold on tub caulk, the electric receptical on one lamp base was loose, and housekeeping didn't come in to freshen the room when requested."

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

10/10 Excellent

"Terrific base accommodation. Clean, efficient. I use this place whenever I’m in the area. I’m"

Frequently asked questions

How much does a hotel room cost in Poplar Bluff?

You can find top hotels in Poplar Bluff from CNY387 with options to suit your budget and needs. Motel 6 Poplar Bluff, MO is one low-cost option that's popular with our travelers. To find an affordable hotel in Poplar Bluff that meets all of your requirements, just apply filters on Hotels.com and sort hotels by "Price: low to high".

How can I find deals and earn rewards at Poplar Bluff hotels?

Discover great deals on Poplar Bluff hotel stays with Hotels.com. Take a look at hotel prices mid-week or during the low season as to find those off-peak deals. If it's a spontaneous trip, check out our last-minute deals on Poplar Bluff hotels.

Can I book Poplar Bluff hotels with free cancellation?

It's easy to book a refundable Poplar Bluff hotel on Hotels.com. Simply filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

What are some top pet-friendly hotels in Poplar Bluff?

Our travelers' favorite pet-friendly hotels in Poplar Bluff include:

Drury Inn & Suites Poplar Bluff: A hotel with a guest rating of 9.4 out of 10
Holiday Inn Poplar Bluff by IHG: A hotel with a guest rating of 8.8

You can also use the "Amenities" filter in your search on Hotels.com and check "Pet friendly" to discover more pet-friendly hotels in Poplar Bluff.

What are some of the best kid-friendly hotels in Poplar Bluff?

One of the best Poplar Bluff hotels for kids is Drury Inn & Suites Poplar Bluff. Drury Inn & Suites Poplar Bluff is a kid-friendly hotel with a guest score of 9.4 out of 10 offering family-friendly amenities like an outdoor pool and a hot tub, plus free cribs in guestrooms. Discover more kid-friendly hotels in Poplar Bluff by using the Hotels.com "Family friendly" filter in your search.

What are the top Poplar Bluff hotels with a pool?

For some added luxury, discover the best Poplar Bluff hotels with a pool. Drury Inn & Suites Poplar Bluff is a great hotel with an outdoor pool and an indoor pool, and a guest rating of 9.4 out of 10. Plus, you can make the most of its hot tub and free buffet breakfast. Holiday Inn Poplar Bluff by IHG is a popular hotel that features an indoor pool along with a restaurant and a bar/lounge. To find more stays in Poplar Bluff with a pool, use the "Amenities" filter on Hotels.com in your search and select "Pool".

What are some of the best Poplar Bluff hotels with free parking?

If you're driving, a great Poplar Bluff hotel with free parking is a bonus. Our travelers' favorites include:

Drury Inn & Suites Poplar Bluff: A hotel with an average guest rating of 9.4 out of 10
Fairfield Inn & Suites by Marriott Poplar Bluff: A hotel with an average guest rating of 9.4
Hampton Inn Poplar Bluff: A hotel with an average guest rating of 9.4

What are some popular hotels in central Poplar Bluff?

If you're looking for hotels in central Poplar Bluff, check out Drury Inn & Suites Poplar Bluff and Holiday Inn Poplar Bluff by IHG. Travelers love Drury Inn & Suites Poplar Bluff for its location, as well as the outdoor pool, hot tub and free buffet breakfast this hotel offers. Holiday Inn Poplar Bluff by IHG is another popular central hotel with an indoor pool, a restaurant and a bar/lounge.

What accommodations do travelers like in Poplar Bluff?

Guests like Holiday Inn Poplar Bluff by IHG, Hampton Inn Poplar Bluff and Motel 6 Poplar Bluff, MO.

Can I book a refundable hotel in Poplar Bluff?

If you need the flexibility to change your travel plans to Poplar Bluff, most properties provide refundable* rates you can book. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

Where should I consider staying in Poplar Bluff if I'm looking for a budget-friendly accommodation?

A few inexpensive options worth considering are Hampton Inn Poplar Bluff, Comfort Inn Poplar Bluff North and Bullwinkles Rustic Lodge.

Where can I stay in Poplar Bluff if I want a vacation rental instead of a hotel?

Browse 6 vacation homes on our site.

Keep exploring

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