Hotels in Jackson

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Top 5 hotels in Jackson at a glance

1. Drury Inn & Suites Jackson MO — 3-star hotel in Jackson. Guest rating: 9.6/10 — Exceptional.
2. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau — 3-star hotel in Jackson. Guest rating: 9.0/10 — Wonderful.
3. Comfort Suites Jackson-Cape Girardeau — 2.5-star hotel in Jackson. Guest rating: 8.2/10 — Very Good.
4. Tru By Hilton Cape Girardeau — 2.5-star hotel in Cape Girardeau. Guest rating: 9.6/10 — Exceptional.
5. Drury Plaza Hotel Cape Girardeau Conference Center — 3-star hotel in Cape Girardeau. Guest rating: 9.6/10 — Exceptional.

Where to stay in Jackson?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Jackson on Hotels.com. These Jackson hotels consistently deliver on comfort, location and traveler experience. Last updated on August 13, 2026.

1. Drury Inn & Suites Jackson MO

Jackson

CNY540

CNY570 total

includes taxes & fees

Aug 23 - Aug 24

Hypo-allergenic bedding available, desk, laptop workspace

2. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

CNY625

CNY676 total

includes taxes & fees

Aug 26 - Aug 27

1 bedroom, desk, iron/ironing board, WiFi (free)

3. Comfort Suites Jackson-Cape Girardeau

Jackson

CNY570

CNY617 total

includes taxes & fees

Aug 16 - Aug 17

Room, 2 Queen Beds, Accessible, Bathtub (Mobility & Hearing)

4. Tru By Hilton Cape Girardeau

Cape Girardeau

CNY603

CNY686 total

includes taxes & fees

Aug 23 - Aug 24

5. Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

CNY675

CNY761 total

includes taxes & fees

Aug 23 - Aug 24

Desk, laptop workspace, blackout drapes, iron/ironing board

6. Drury Inn & Suites Cape Girardeau

Cape Girardeau

CNY607

CNY685 total

includes taxes & fees

Aug 21 - Aug 22

Suite, 1 Bedroom (Feature) | Premium bedding, down comforters, pillowtop beds, in-room safe

7. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Cape Girardeau

CNY695

CNY784 total

includes taxes & fees

Sep 13 - Sep 14

Desk, laptop workspace, blackout drapes, cribs (free)

Room, 2 Queen Beds, Accessible (Tub) | Desk, laptop workspace, blackout drapes, cribs (free)

8. Pear Tree Inn Cape Girardeau West

Cape Girardeau

CNY486

CNY548 total

includes taxes & fees

Aug 23 - Aug 24

Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave | In-room safe, desk, iron/ironing board, cribs (free)

9. Hampton Inn Cape Girardeau I 55 East

Cape Girardeau

CNY714

CNY805 total

includes taxes & fees

Aug 23 - Aug 24

10. Fairfield Inn & Suites by Marriott Cape Girardeau

Cape Girardeau

CNY625

CNY705 total

includes taxes & fees

Sep 13 - Sep 14

Jackpot Suite | Living area | LED TV, Netflix, Hulu, first-run movies

11. The Riverview

Cape Girardeau

CNY771

CNY870 total

includes taxes & fees

Aug 26 - Aug 27

Egyptian cotton sheets, premium bedding, down comforters

12. Quality Inn Cape Girardeau North

Cape Girardeau

CNY416

CNY470 total

includes taxes & fees

Sep 14 - Sep 15

13. Courtyard by Marriott Cape Girardeau Downtown

Cape Girardeau

CNY844

CNY956 total

includes taxes & fees

Aug 24 - Aug 25

14. Perryville RV Resort

Perryville

CNY448

CNY513 total

includes taxes & fees

Sep 14 - Sep 15

In-room safe, desk, blackout drapes, soundproofing

15. Candlewood Suites Cape Girardeau by IHG

Cape Girardeau

CNY553

CNY661 total

includes taxes & fees

Aug 16 - Aug 17

Standard Room, 1 King Bed, Non Smoking (NRF) | Desk, WiFi (free)

16. Town House Inn Cape Giradreau

Cape Girardeau

CNY472

CNY552 total

includes taxes & fees

Sep 5 - Sep 6

17. EC Reed's Mercantile and Hotel

Marble Hill

CNY567

CNY617 total

includes taxes & fees

Sep 14 - Sep 15

Deluxe Cottage, Multiple Beds, Non Smoking (West End Cottage) | Living area

Romantic Cottage, 1 King Bed, Non Smoking (Indigo Cottage) | Egyptian cotton sheets, premium bedding, pillowtop beds, blackout drapes

18. Makanda Inn

Makanda

CNY1,767

CNY2,014 total

includes taxes & fees

Aug 16 - Aug 17

Suite 11, 1 Queen Bed with Sofa bed, Pets Allowed | Interior

19. The Atrium - A Boutique Hotel

Perryville

CNY510

CNY1,076 total

includes taxes & fees

Sep 14 - Sep 15

20. Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Murphysboro

CNY769

CNY853 total

includes taxes & fees

Aug 23 - Aug 24

View all properties

Go beyond your typical stay in Jackson

Pet friendly

Pool

Family friendly

Our prices for hotels in Jackson are cheapest in July

Top landmarks in Jackson

Litz Park

8.6/10 (14 reviews)

Litz Park is worth a visit, located 0.8 mi (1.3 km) from central Jackson.

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Indian Creek Wild Area

Indian Creek Wild Area is 11.2 mi (18 km) from central Jackson, why not stop by during your stay.

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Lake Boutin

Lake Boutin is 11 mi (17.6 km) from central Jackson, why not stop by during your stay.

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Vancill Hollow Natural Area

Vancill Hollow Natural Area is 11.6 mi (18.7 km) from central Jackson, why not stop by during your stay.

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Learn more about Jackson

Jackson is well-known for its attractions such as Trail of Tears State Park and Mississippi River. This family-friendly city has something for everyone including restaurants as well as sights like Indian Creek Wild Area and Lake Boutin. All are within a rural setting.

See all hotels in Jackson

A historic building with a clock tower, surrounded by lush green grass and trees.

Check out reviews of Jackson hotels guests love

Candlewood Suites Cape Girardeau by IHG

10/10 Excellent

"Property was clean a room was stocked. Had microwave refrigerator and a stove refrigerator had working ice maker. Great room for the price"

Drury Inn & Suites Jackson MO

10/10 Excellent

"The kick-back after a day of travel is a most welcome amenity, and the breakfast is always great. Drury is our favorite place to stay."

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

8/10 Good

"The room was clean and staff was friendly. The breakfast was alright. The hot stuff didn't seem very fresh for only being 30 minutes into breakfast."

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent

"20/10 stars! Was highly impressed with EVERY single aspect of our stay here."

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

10/10 Excellent

"Great location! Stayed in town to move my Niece on campus at SIUC"

The Riverview

10/10 Excellent

"Very well kept"

Drury Inn & Suites Cape Girardeau

10/10 Excellent

"Clean rooms and delicious buffet"

Pear Tree Inn Cape Girardeau West

10/10 Excellent

"Very friendly professional and helpful staff. Clean comfortable room. Close parking. Close to lots of shopping"

Tru By Hilton Cape Girardeau

10/10 Excellent

"Clean"

Frequently asked questions

How much does a hotel room cost in Jackson?

You can choose a great hotel in Jackson from CNY470 with properties to suit all budgets and needs. If you're after an affordable hotel in Jackson that meets all of your requirements, set your filters and then sort the results by "Price: low to high".

How can I find deals and earn rewards at Jackson hotels?

Discover great deals on Jackson hotel stays with Hotels.com. You can also look at hotel prices mid-week or during the low season to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Jackson hotels.

Can I book Jackson hotels with free cancellation?

To book a refundable Jackson hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

What are some top pet-friendly hotels in Jackson?

Our travelers' favorite pet-friendly hotels in Jackson include:

Drury Inn & Suites Jackson MO: A hotel with a guest rating of 9.6 out of 10

You can also use the "Amenities" filter in your search on Hotels.com and check "Pet friendly" to discover more pet-friendly hotels in Jackson.

What are some of the best kid-friendly hotels in Jackson?

One of the best Jackson hotels for kids is La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau is a kid-friendly hotel with a guest score of 8.8 out of 10 offering family-friendly amenities like an indoor pool and free parking, plus free cribs in guestrooms. Discover more kid-friendly hotels in Jackson by using the Hotels.com "Family friendly" filter in your search.

What are the top Jackson hotels with a pool?

For a little extra luxury, discover some of the best Jackson hotels with a pool. Drury Inn & Suites Jackson MO is a great hotel with an indoor pool and a guest rating of 9.6 out of 10. Plus, you can make the most of its hot tub and free buffet breakfast. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau is a popular hotel that features an indoor pool along with a free self-serve breakfast and a 24-hour gym. To find more stays in Jackson with a pool, use the "Amenities" filter on Hotels.com in your search and select "Pool".

What are some of the best Jackson hotels with free parking?

If you're driving, a great Jackson hotel with free parking is a bonus. Our travelers' favorites include:

Drury Inn & Suites Jackson MO: A hotel with an average guest rating of 9.6 out of 10
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau: A hotel with an average guest rating of 8.8
Comfort Suites Jackson-Cape Girardeau: A hotel with an average guest rating of 8.2

What are some popular hotels in central Jackson?

For hotels in central Jackson, check out Drury Inn & Suites Jackson MO and La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau. Travelers love Drury Inn & Suites Jackson MO for its location, as well as the indoor pool, hot tub and free buffet breakfast this hotel offers. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau is another popular central hotel with an indoor pool, a free self-serve breakfast and a 24-hour gym.

What accommodations do travelers like in Jackson?

Guests like La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau, Drury Inn & Suites Jackson MO and Comfort Suites Jackson-Cape Girardeau.

Can I book a refundable hotel in Jackson?

If you need the flexibility to change your travel plans to Jackson, most properties offer refundable* rates you can book. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

Where should I consider staying in Jackson if I'm looking for a budget-friendly accommodation?

Comfort Suites Jackson-Cape Girardeau is an accommodation you might want to consider that'll save you money.

Where can I stay in Jackson if I want a vacation home instead of a hotel?

Browse 5 vacation homes on our site.

Hotels in Jackson

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Top 5 hotels in Jackson at a glance

Where to stay in Jackson?

1. Drury Inn & Suites Jackson MO

2. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3. Comfort Suites Jackson-Cape Girardeau

4. Tru By Hilton Cape Girardeau

5. Drury Plaza Hotel Cape Girardeau Conference Center

6. Drury Inn & Suites Cape Girardeau

7. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

8. Pear Tree Inn Cape Girardeau West

9. Hampton Inn Cape Girardeau I 55 East

10. Fairfield Inn & Suites by Marriott Cape Girardeau

11. The Riverview

12. Quality Inn Cape Girardeau North

13. Courtyard by Marriott Cape Girardeau Downtown

14. Perryville RV Resort

15. Candlewood Suites Cape Girardeau by IHG

16. Town House Inn Cape Giradreau

17. EC Reed's Mercantile and Hotel

18. Makanda Inn

19. The Atrium - A Boutique Hotel

20. Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Go beyond your typical stay in Jackson

Price trends for hotels in Jackson

Typical weather for Jackson

Top landmarks in Jackson

Litz Park

Indian Creek Wild Area

Lake Boutin

Vancill Hollow Natural Area

Learn more about Jackson

Check out reviews of Jackson hotels guests love

Candlewood Suites Cape Girardeau by IHG

Drury Inn & Suites Jackson MO

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Drury Plaza Hotel Cape Girardeau Conference Center

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

The Riverview

Drury Inn & Suites Cape Girardeau

Pear Tree Inn Cape Girardeau West

Tru By Hilton Cape Girardeau

Frequently asked questions

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