Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
The center of Sikeston is home to cultural attractions like Sikeston Depot Museum, so you might want to stop by during your stay. If you want to experience more of the culture Sikeston has to offer, head to Central Park and City of Miner Convention Center.
Admired for its riverfront and university life, Sikeston features attractions such as Sikeston Depot Museum and Central Park. This family-friendly city's sights include City of Miner Convention Center and visitors speak highly of the local restaurants.
Drury Plaza Hotel Cape Girardeau Conference Center
10/10 Excellent
"This is the best hotel experience for the price that I’ve ever had, and I travel a lot. Very generous social time with three free drinks and lots of complementary food. Everyone was lovely, bed comfortable, perfect temperature and no stale smell. Very clean. And so well priced! I wish all hotels were like this one!"
"All staff were nice and accommodating. The dining area was clean and stocked with various food options during dining times. The room was very clean and tidy."
"Beautiful hotel. Very clean, modern and friendly staff. Definitely would recommend to anyone coming to that area and will stay there every time we visit the city."
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
10/10 Excellent
"My partner and I were in town for a family wedding and stayed for 3 nights. The staff at this hotel were amazing! They were, over the top, friendly and helpful with anything we needed. They allowed us to gather with family outside on the patio and checked on us several times. The room was clean, the bed was super comfortable, breakfast was great and we loved the patio area. Overall, it was a wonderful experience!"
Can I book a refundable accommodation in Sikeston?
If you're looking for the flexibility to change your travel plans to Sikeston, most properties provide refundable* rates you can book. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Sikeston if I want a cheap accommodation?
What will the weather in Sikeston be like during my vacation?
The warmest months in Sikeston are usually July and August with an average temp of 77°F. January and February are the chilliest months when the average temp is 41°F. The rainiest months are April and March.
Why should I book my Sikeston hotel with Hotels.com?
There are plenty of reasons to book your Sikeston travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.